Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension

Molecular Metabolism - Tập 2 - Trang 92-102 - 2013
Sebastian Schmeisser1,2, Steffen Priebe3, Marco Groth4, Shamci Monajembashi5, Peter Hemmerich5, Reinhard Guthke3, Matthias Platzer4, Michael Ristow1,6,7
1Department of Human Nutrition, Institute of Nutrition, University of Jena, Jena D-07743, Germany
2Leibniz Graduate School of Aging, Leibniz Institute for Age Research, Fritz-Lipmann-Institute, Jena D-07745, Germany
3Systems Biology and Bioinformatics Group, Leibniz Institute for Natural Product Research and Infection Biology, Hans-Knöll-Institute, Jena D-07745, Germany
4Genome Analysis Group, Leibniz Institute for Age Research, Fritz-Lipmann-Institute, Jena D-07745, Germany
5Imaging Facility Group, Leibniz Institute for Age Research, Fritz-Lipmann-Institute, Jena D-07745, Germany
6Energy Metabolism Laboratory, Department of Health Sciences and Technology, ETH Zürich (Swiss Federal Institute of Technology Zurich), Schwerzenbach/Zürich CH 8603, Switzerland
7Department of Clinical Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal D-14558, Germany

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