Extensive production of Neospora caninum tissue cysts in a carnivorous marsupial succumbing to experimental neosporosis
Tóm tắt
Experimental infections of Sminthopsis crassicaudata, the fat-tailed dunnart, a carnivorous marsupial widely distributed throughout the arid and semi-arid zones of Australia, show that this species can act as an intermediate host for Neospora caninum. In contrast to existing models that develop relatively few N. caninum tissue cysts, dunnarts offer a new animal model in which active neosporosis is dominated by tissue cyst production. The results provide evidence for a sylvatic life cycle of N. caninum in Australia between marsupials and wild dogs. It establishes the foundation for an investigation of the impact and costs of neosporosis to wildlife.
Tài liệu tham khảo
Savolainen P, Leitner T, Wilton AN, Matisoo-Smith E, Lundeberg J: A detailed picture of the origin of the Australian dingo, obtained from the study of mitochondrial DNA. Proc Natl Acad Sci USA. 2004, 101: 12387-12390. 10.1073/pnas.0401814101.
King JS, Šlapeta J, Jenkins DJ, Al-Qassab SE, Ellis JT, Windsor PA: Australian dingoes are definitive hosts of Neospora caninum. Int J Parasitol. 2010, 40: 945-950. 10.1016/j.ijpara.2010.01.008.
Al-Qassab SE, Reichel MP, Ellis JT: On the biological and genetic diversity in Neospora caninum. Diversity. 2010, 2: 411-438. 10.3390/d2030411.
Dubey JP, Schares G, Ortega-Mora LM: Epidemiology and control of neosporosis and Neospora caninum. Clin Microbiol Rev. 2007, 20: 323-367. 10.1128/CMR.00031-06.
King JS, Jenkins DJ, Ellis JT, Fleming P, Windsor PA, Šlapeta J: Implications of wild dog ecology on the sylvatic and domestic life cycle of Neospora caninum in Australia. Vet J. 2011, 188: 24-33. 10.1016/j.tvjl.2010.03.002.
Kang SW, Park SS, Choe SE, Jean YH, Jung SC, Kim K, Van Quyen D: Characterization of tissue distribution and histopathological lesions in Neospora caninum experimentally infected gerbils. Parasitol Res. 2009, 104: 1261-1268. 10.1007/s00436-008-1322-8.
Pipano E, Shkap V, Fish L, Savitsky I, Perl S, Orgad U: Susceptibility of Psammomys obesus and Meriones tristrami to tachyzoites of Neospora caninum. J Parasitol. 2002, 88: 314-319.
Hůrkova-Hofmannová L, Václavek P, Skorič M, Fictum P, Modrý D: Multimammate rat (Mastomys natalensis), Tristram's jird (Meriones tristrami) and Wagner's gerbil (Gerbillus dasyurus) as laboratory models of acute neosporosis. Res Vet Sci. 2007, 82: 377-381. 10.1016/j.rvsc.2006.10.004.
Gondim LFP, Pinheiro AM, Santos POM, Jesus EEV, Ribeiro MB, Fernandes HS, Almeida MAO, Freire SM, Meyer R, McAllister MM: Isolation of Neospora caninum from the brain of a naturally infected dog, and production of encysted bradyzoites in gerbils. Vet Parasitol. 2001, 101: 1-7. 10.1016/S0304-4017(01)00493-9.
McGuire AM, McAllister MM, Jolley WR, Anderson-Sprecher RC: A protocol for the production of Neospora caninum tissue cysts in mice. J Parasitol. 1997, 83: 647-651. 10.2307/3284241.
Thompson RCA, Lymbery AJ, Smith A: Parasites, emerging disease and wildlife conservation. Int J Parasitol. 2010, 40: 1163-1170. 10.1016/j.ijpara.2010.04.009.
Cooper SJB, Adams M, Labrinidis A: Phylogeography of the Australian dunnart Sminthopsis crassicaudata (Marsupialia: Dasyuridae). Aust J Zool. 2000, 48: 461-473. 10.1071/ZO00014.
Strahan R, van Dyck S, (Eds): The mammals of Australia. 2008, Sydney: Publisher: New Holland
Miller CMD, Quinn HE, Windsor PA, Ellis JT: Characterisation of the first Australian isolate of Neospora caninum from cattle. Aust Vet J. 2002, 80: 620-625. 10.1111/j.1751-0813.2002.tb10967.x.
Mark M, Teletin M, Antal C, Wendling O, Auwerx J, Heikkinen S, Khetchoumian K, Argmann CA, Dgheem M: Histopathology in mouse metabolic investigations. Curr Protoc Mol Biol. 2007, Chapter 29 (Unit 29B): 24-
Müller N, Zimmermann V, Hentrich B, Gottstein B: Diagnosis of Neospora caninum and Toxoplasma gondii infection by PCR and DNA hybridization immunoassay. J Clin Microbiol. 1996, 34: 2850-2852.
Šlapeta JR, Koudela B, Votýpka J, Modrý D, Hořejš R, Lukeš J: Coprodiagnosis of Hammondia heydorni in dogs by PCR based on ITS 1 rRNA: Differentiation from morphologically indistinguishable oocysts of Neospora caninum. Vet J. 2002, 163: 147-154. 10.1053/tvjl.2001.0599.
Ellis JT: Polymerase chain reaction approaches for the detection of Neospora caninum and Toxoplasma gondii. Int J Parasitol. 1998, 28: 1053-1060. 10.1016/S0020-7519(98)00096-4.
Basso W, Schares S, Barwald A, Herrmann DC, Conraths FJ, Pantchev N, Vrhovec MG, Schares G: Molecular comparison of Neospora caninum oocyst isolates from naturally infected dogs with cell culture-derived tachyzoites of the same isolates using nested polymerase chain reaction to amplify microsatellite markers. Vet Parasitol. 2009, 160: 43-50. 10.1016/j.vetpar.2008.10.085.
Pedraza-Díaz S, Marugán-Hernández V, Collantes-Fernández E, Regidor-Cerrillo J, Rojo-Montejo S, Gómez-Bautista M, Ortega-Mora LM: Microsatellite markers for the molecular characterization of Neospora caninum: application to clinical samples. Vet Parasitol. 2009, 166: 38-46. 10.1016/j.vetpar.2009.07.043.
Baszler TV, Adams S, Vander-Schalie J, Mathison BA, Kostovic M: Validation of a commercially available monoclonal antibody-based competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to Neospora caninum in cattle. J Clin Microbiol. 2001, 39: 3851-3857. 10.1128/JCM.39.11.3851-3857.2001.
Dubey JP, Lindsay DS: Gerbils (Meriones unguiculatus) are highly susceptible to oral infection with Neospora caninum oocysts. Parasitol Res. 2000, 86: 165-168. 10.1007/s004360050027.
McAllister MM, Parmley SF, Weiss LM, Welch VJ, McGuire AM: An immunohistochemical method for detecting bradyzoite antigen (BAG5) in Toxoplasma gondii-infected tissues cross-reacts with a Neospora caninum bradyzoite antigen. J Parasitol. 1996, 82: 354-355. 10.2307/3284181.
Vonlaufen N, Müller N, Keller N, Naguleswaran A, Bohne W, McAllister MM, Björkman C, Müller E, Caldelari R, Hemphill A: Exogenous nitric oxide triggers Neospora caninum tachyzoite-to-bradyzoite stage conversion in murine epidermal keratinocyte cell cultures. Int J Parasitol. 2002, 32: 1253-1265. 10.1016/S0020-7519(02)00126-1.
Weiss LM, Ma YF, Halonen S, McAllister MM, Zhang YW: The in vitro development of Neospora caninum bradyzoites. Int J Parasitol. 1999, 29: 1713-1723. 10.1016/S0020-7519(99)00130-7.
Dubey JP, Garner MW, Willette MM, Batey KL, Gardiner CH: Disseminated toxoplasmosis in magpie geese (Anseranas semipalmata) with large numbers of tissue cysts in livers. J Parasitol. 2001, 87: 219-223.
Hartley WJ, Dubey JP, Spielman DS: Fatal toxoplasmosis in koalas (Phascolarctos cinereus). J Parasitol. 1990, 76: 271-272. 10.2307/3283032.
Parameswaran N, Thompson RCA, Sundar N, Pan S, Johnson M, Smith NC, Grigg ME: Non-archetypal Type II-like and atypical strains of Toxoplasma gondii infecting marsupials of Australia. Int J Parasitol. 2010, 40: 635-640. 10.1016/j.ijpara.2010.02.008.
Sangster C, Bryant B, Campbell-Ward M, King JS, Šlapeta J: Neosporosis in an aborted Southern White Rhinoceros (Ceratotherium simum simum) foetus. J Zoo Wildl Med. 2010, 41: 725-728. 10.1638/2009-0250.1.
Bishop S, King J, Windsor P, Reichel MP, Ellis J, Šlapeta J: The first report of ovine cerebral neosporosis and evaluation of Neospora caninum prevalence in sheep in New South Wales. Vet Parasitol. 2010, 170: 137-142. 10.1016/j.vetpar.2010.01.030.
Barratt J, Al Qassab S, Reichel MP, Ellis JT: The development and evaluation of a nested PCR assay for detection of Neospora caninum and Hammondia heydorni in feral mouse tissues. Mol Cell Probes. 2008, 22: 228-233. 10.1016/j.mcp.2008.03.001.