Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial

The Lancet - Tập 352 Số 9122 - Trang 98-101 - 1998
Trevor J. Powles1, Rosalind A. Eeles2, S. Ashley1, Douglas F. Easton3, Jenny C. Chang1, Mitch Dowsett1, Alwynne Tidy1, Jenny Viggers1, J Davey1
1Royal Marsden NHS Trust, London and Sutton, Surrey, SM2 5PT, UK
2Cancer Genetics Team, Institute of Cancer Research, Sutton
3Genetic Epidemiology Unit, Strangeways Laboratory, Cambridge

Tóm tắt

Từ khóa


Tài liệu tham khảo

Jordan, 1976, Effect of tamoxifen (ICI 46, 474) on initiation and growth of DMBA-induced rat mammary carcinomata, Eur J Cancer, 12, 419, 10.1016/0014-2964(76)90030-X

1983, Controlled trial of tamoxifen as adjuvant agent in management of early breast cancer; interim analysis at four years by Nolvadex Adjuvant Trial Organisation, Lancet, i, 257

1988, Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer, N Engl J Med, 319, 1681, 10.1056/NEJM198812293192601

Cuzick, 1985, Tamoxifen and contralateral breast cancer, Lancet, ii, 282, 10.1016/S0140-6736(85)90338-1

Powles, 1989, A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer, Br J Cancer, 60, 126, 10.1038/bjc.1989.235

Love, 1992, Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer, N Engl J Med, 326, 852, 10.1056/NEJM199203263261302

Johnston, 1993, Effect of oestrogen receptor status and time on the intra-tumoural accumulation of tamoxifen and N-desmethyltamoxifen following short-term therapy in human primary breast cancer, Breast Cancer Res Treat, 28, 241, 10.1007/BF00666585

Cohn, 1988, Lipoprotein and cholesterol concentrations in the plasma of human subjects as measured in the food and fasting status, Clin Chem, 34, 2456, 10.1093/clinchem/34.12.2456

1998, Tamoxifen for early breast cancer: an overview of the randomised trials, Lancet, 351, 1451, 10.1016/S0140-6736(97)11423-4

Stat, 1998, Breast cancer incidence in the breast cancer prevention trial, J Natl Cancer Inst, 90, 648, 10.1093/jnci/90.9.648

Powles, 1996, Effect of tamoxifen on bone mineral density measured by dual-energy X-ray absorptiometry in healthy premenopausal and postmenopausal women, J Clin Oncol, 14, 78, 10.1200/JCO.1996.14.1.78

Powles T, Bourne T, Athanasiou S, et al. The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy postmenopausal women on tamoxifen or placebo. Br J Cancer (in press).

Claus, 1990, Age at onset as an indicator of familial risk of breast cancer, Am J Epidemiol, 131, 66, 10.1093/oxfordjournals.aje.a115616

Osin, 1998, Hormone status of in-situ cancer in BRCA1 and BRCA2 mutation carriers, Lancet, 351, 1487, 10.1016/S0140-6736(98)24020-7

Jordan, 1991, Suppression of mouse mammary tumorigenesis by long-term tamoxifen therapy, J Natl Cancer Inst, 83, 492, 10.1093/jnci/83.7.492

Rutqvist, 1995, Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies. Stockholm Breast Cancer Study Group, J Natl Cancer Inst, 87, 645, 10.1093/jnci/87.9.645

Powles, 1995, Tamoxifen therapy and carcinogenic risk, J Natl Cancer Inst, 87, 1343, 10.1093/jnci/87.18.1343

Scully, 1997, Association of the BRCA1 gene product with Rad51 in meiotic and mitotic cells, Cell, 88, 265, 10.1016/S0092-8674(00)81847-4