The effect of therapeutic hypothermia on the expression of inflammatory response genes following moderate traumatic brain injury in the rat

Aibiki, 1999, Effects of moderate hypothermia on systemic and internal jugular plasma IL-6 levels after traumatic brain injury in humans, J. Neurotrauma, 16, 225, 10.1089/neu.1999.16.225 Allan, 2000, The role of pro- and anti-inflammatory cytokines in neurodegeneration, Ann. N. Y. Acad. Sci., 917, 84, 10.1111/j.1749-6632.2000.tb05373.x Allan, 2001, Cytokines and acute neurodegeneration, Nat. Rev., Neurosci., 2, 734, 10.1038/35094583 Aoki, 2001, Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain, Mol. Brain Res., 95, 117, 10.1016/S0169-328X(01)00255-8 Baugh, 2002, Macrophage migration inhibitory factor, Crit. Care Med., 30, S27, 10.1097/00003246-200201001-00004 Baugh, 2003, Macrophage migration inhibitory factor: a neuroendocrine modulator of chronic inflammation, J. Endocrinol., 179, 15, 10.1677/joe.0.1790015 Benveniste, 1992, Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action, Am. J. Physiol., 263, C1, 10.1152/ajpcell.1992.263.1.C1 Bethea, 2002, Targeting the host inflammatory response in traumatic spinal cord injury, Curr. Opin. Neurol., 15, 355, 10.1097/00019052-200206000-00021 Borie-Moller, 1998, The effect of hypothermia on the expression of neurotrophins mRNA in the hippocampus following transient cerebral ischemia in the rat, Mol. Brain Res., 63, 163, 10.1016/S0169-328X(98)00286-1 Campbell, 1993, Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6, Proc. Natl. Acad. Sci. U. S. A., 90, 10061, 10.1073/pnas.90.21.10061 Chatzipantei, 1999, Effects of moderate hypothermia on constitutive and inducible nitric oxide synthase activities after traumatic brain injury in the rat, J. Neurochem., 72, 2047, 10.1046/j.1471-4159.1999.0722047.x Chatzipanteli, 2000, Importance of post-traumatic hypothermia and hyperthermia on the inflammatory response after fluid percussion brain injury: biochemical and immunocytochemical studies, J. Cereb. Blood Flow Metab., 20, 531, 10.1097/00004647-200003000-00012 Chatzipanteli, 2002, Hypothermia reduces the activity of NF-κB after parasagittal fluid-percussion brain injury, J. Neurotrauma, 19, 1323 Clifton, 1991, Marked protection by moderate hypothermia after experimental traumatic brain injury, J. Cereb. Blood Flow Metab., 11, 114, 10.1038/jcbfm.1991.13 Clifton, 2001, Lack of effect of induction of hypothermia after acute brain injury, N. Engl. J. Med., 344, 556, 10.1056/NEJM200102223440803 Clifton, 2002, Hypothermia on admission in patients with severe brain injury, J. Neurotrauma, 19, 293, 10.1089/089771502753594864 Csuka, 1999, IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-α, TGF-β1 and blood–brain barrier function, J. Neuroimmunol., 101, 211, 10.1016/S0165-5728(99)00148-4 Daun, 2000, Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic I6Bα, Am. J. Physiol.: Regul., Integr. Comp. Physiol., 279, R1043 D'Cruz, 2002, Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor activation, J. Cereb. Blood Flow Metab., 22, 843, 10.1097/00004647-200207000-00009 Dietrich, 1994, Post-traumatic brain hypothermia reduces histopathological damage following concussive brain injury in the rat, Acta Neuropathol. (Berl.), 87, 250, 10.1007/BF00296740 Dietrich, 1996, Brain damage and temperature: cellular and molecular mechanisms, Adv. Neurol., 71, 177 Dietrich, 1999, Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats, Exp. Neurol., 158, 444, 10.1006/exnr.1999.7115 Dietrich, 1999, Sequential changes in glial fibrillary acidic protein and gene expression following parasagittal fluid-percussion brain injury in rats, J. Neurotrauma, 16, 567, 10.1089/neu.1999.16.567 Dutcher, 1999, Patterns of immediate early gene mRNA expression following rodent and human traumatic brain injury, Neurol. Res., 21, 234, 10.1080/01616412.1999.11740924 Flanders, 1998, Transforming growth factor-βS in neurodegenerative disease, Prog. Neurobiol., 54, 71, 10.1016/S0301-0082(97)00066-X Friedman, 2001, Intraischemic but not postischemic hypothermia prevents non-selective hippocampal downregulation of AMPA and NMDA receptor gene expression after global ischemia, Mol. Brain Res., 86, 34, 10.1016/S0169-328X(00)00252-7 Ghimakar, 1996, Chemokine expression in rat stab wound brain injury, J. Neurosci. Res., 46, 727, 10.1002/(SICI)1097-4547(19961215)46:6<727::AID-JNR9>3.0.CO;2-H Glabinski, 1996, Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain, J. Immunol., 156, 4363, 10.4049/jimmunol.156.11.4363 Goss, 1995, Hypothermia attenuates the normal increase in interleukin 1β RNA and nerve growth factor following traumatic brain injury in the rat, J. Neurotrauma, 12, 159, 10.1089/neu.1995.12.159 Gregersen, 2003, Macrophage migration inhibitory factor, MIF Alleles, and the genetics of inflammatory disorders: incorporating disease outcome into the definition of phenotype, Arthritis Rheum., 48, 1171, 10.1002/art.10880 Gruol, 1997, Physiological and pathological roles of interleukin-6 in the central nervous system, Mol. Neurobiol., 15, 307, 10.1007/BF02740665 Han, 2002, Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation, J. Neurosci., 22, 3921, 10.1523/JNEUROSCI.22-10-03921.2002 Han, 2003, Mild hypothermia inhibits nuclear factor-6B translocation in experimental stroke, J. Cereb. Blood Flow Metab., 22, 589, 10.1097/01.WCB.0000059566.39780.8D Haskill, 1990, Identification of three related human GRO genes encoding cytokine functions, Proc. Natl. Acad. Sci. U. S. A., 87, 7732, 10.1073/pnas.87.19.7732 Hausman, 1998, Selective chemokine mRNA expression following brain injury, Brain Res., 788, 49, 10.1016/S0006-8993(97)01160-8 Hicks, 2000, Hypothermia differentially increases extracellular signal-regulated kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest, Neuroscience, 98, 677, 10.1016/S0306-4522(00)00169-X Hu, 1995, Alterations of Ca2−/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia, Neuroscience, 68, 1003, 10.1016/0306-4522(95)00213-3 Huang, 2000, Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation, Immunol. Rev., 177, 52, 10.1034/j.1600-065X.2000.17709.x Jiang, 1992, Moderate hypothermia reduces blood–brain barrier disruption following traumatic brain injury in the rat, Acta Neuropathol., 84, 495, 10.1007/BF00304468 Jiang, 2000, Effects of long-term mild hypothermia therapy in patients with severe traumatic brain injury: 10 year follow-up review of 87 cases, J. Neurosurg., 93, 546, 10.3171/jns.2000.93.4.0546 Kamme, 1996, Induction of junD mRNA after transient forebrain ischemia in the rat. Effect of hypothermia, Mol. Brain Res., 43, 51, 10.1016/S0169-328X(96)00151-9 Kamme, 1995, Biphasic expression of the Fos and Jun families of transcription factors following transient forebrain ischaemia in the rat. Effect of hypothermia, Eur. J. Neurosci., 7, 2007, 10.1111/j.1460-9568.1995.tb00623.x Kataoka, 2002, Effect of cold-ischemia on C-X-C chemokine expression and neutrophils accumulation in the graft liver after orthotropic liver transplantation in rats, Transplantation, 73, 1730, 10.1097/00007890-200206150-00007 Kinoshita, 2002, The effect of brain temperature on hemoglobin extravasation after traumatic brain injury, J. Neurosurg., 97, 945, 10.3171/jns.2002.97.4.0945 Kinoshita, 2002, Interleukin-1β messenger ribonucleic acid and protein levels after fluid-percussion brain injury in rats: importance of injury severity and brain temperature, Neurosurgery, 5, 1105 Knoblach, 1998, Interleukin-10 improves outcome and alters proinflammatory cytokine expression after traumatic brain injury, Exp. Neurol., 153, 143, 10.1006/exnr.1998.6877 Knoblach, 1999, Early neuronal expression of tumor necrosis factor-α after experimental brain injury contributes to neurological impairment, J. Neuroimmunol., 95, 115, 10.1016/S0165-5728(98)00273-2 Kobori, 2002, Altered expression of novel genes in the cerebral cortex following experimental brain injury, Mol. Brain Res., 104, 148, 10.1016/S0169-328X(02)00331-5 Krieglstein, 1996, Distinct modulatory actions of TGF-beta and LIF on neurotrophins-mediated survival of developing sensory neurons, Neurochem. Res., 21, 843, 10.1007/BF02532308 Kumar, 1996, Expression of c-fos and fos-B proteins following transient forebrain ischemia: effect of hypothermia, Mol. Brain Res., 42, 337, 10.1016/S0169-328X(96)00181-7 Li, 2004, Differential gene expression in hippocampus following experimental brain trauma reveals distinct features of moderate and severe injuries, J. Neurotrauma, 9, 1141, 10.1089/0897715041953777 Loddick, 1998, Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat, J. Cereb. Blood Flow Metab., 18, 176, 10.1097/00004647-199802000-00008 Logan, 1999, Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-β2, Eur. J. Neurosci., 11, 2367, 10.1046/j.1460-9568.1999.00654.x Long, 2003, Altered expression of randomly selected genes in mouse hippocampus after traumatic brain injury, J. Neurosci. Res., 71, 710, 10.1002/jnr.10524 Loukinova, 2001, Expression of proangiogenic chemokine GRO 1 in low and high metastatic variants of pam murine squamous cell carcinoma is differentially regulated by IL-1α, EGF and TGF-β1 through NF-6B dependent and independent mechanisms, Int. J. Cancer, 94, 637, 10.1002/ijc.1514 Lue, 2002, Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease, Microbes Infect., 4, 449, 10.1016/S1286-4579(02)01560-5 Mancuso, 2000, Mild hypothermia decreases the incidence of transient ADC reduction detected with diffusion MRI and expression of c-fos and hsp70 mRNA during acute focal ischemia in rats, Brain Res., 887, 34, 10.1016/S0006-8993(00)02963-2 Marciano, 2002, Expression profiling following traumatic brain injury: a review, Neurochem. Res., 10, 1147, 10.1023/A:1020973308941 Marion, 1997, Treatment of traumatic brain injury with moderate hypothermia, N. Engl. J. Med., 336, 540, 10.1056/NEJM199702203360803 Matzilevich, 2002, High-density microarray analysis of hippocampal gene expression following experimental brain injury, J. Neurosci. Res., 67, 646, 10.1002/jnr.10157 McClain, 1991, Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury, J. Lab. Clin. Med., 118, 225 McIntosh, 1998, The Dorothy Russell memorial lecture: the molecular and cellular sequelae of experimental traumatic brain injury—Pathogenic mechanisms, Neuropathol. Appl. Neurobiol., 24, 251, 10.1046/j.1365-2990.1998.00121.x McTigue, 1998, Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury, J. Neurosci. Res., 53, 368, 10.1002/(SICI)1097-4547(19980801)53:3<368::AID-JNR11>3.0.CO;2-1 Morganti-Kossmann, 1997, Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue, Mol. Psychiatry, 2, 133, 10.1038/sj.mp.4000227 Morganti-Kossmann, 2002, Inflammatory response in acute traumatic brain injury: a double-edged sword, Curr. Opin. Crit. Care, 8, 101, 10.1097/00075198-200204000-00002 Nishihira, 2003, Macrophage migration inhibitory factor (MIF): its potential role in tumor growth and tumor-associated angiogenesis, Ann. N.Y. Acad. Sci., 995, 171, 10.1111/j.1749-6632.2003.tb03220.x Ousman, 2001, MIP-1α, MCP-1, GM-CSF, and TNF-α control the immune cell response that mediates rapid phagocytosis of myelin from the adult mouse spinal cord, J. Neurosci., 21, 4649, 10.1523/JNEUROSCI.21-13-04649.2001 Polderman, 2002, Effects of therapeutic hypothermia on intracranial pressure and outcome in patients with severe head injury, Intensive Care Med., 28, 1563, 10.1007/s00134-002-1511-3 Relton, 1997, Cytokines: neurotoxicity and neuroprotection, 225 Resnick, 1994, The effect of hypothermia on the incidence of delayed traumatic intracerebral hemorrhage, Neurosurgery, 34, 252, 10.1227/00006123-199402000-00007 Roberts, 1992, Differential expression of TGF-beta isoforms in embryogenesis suggests specific roles in developing and adult tissues, Mol. Reprod. Dev., 32, 91, 10.1002/mrd.1080320203 Ross, 1994, The presence of tumour necrosis factor in CSF and plasma after severe head injury, Br. J. Neurosurg., 8, 419, 10.3109/02688699408995109 Scherbel, 1999, Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury, Proc. Nat.l Acad. Sci. U. S. A., 96, 18721, 10.1073/pnas.96.15.8721 Shohami, 1994, Closed head injury triggers early production of TNF ∀ and IL-6 by brain tissue, J. Cereb. Blood Flow Metab., 14, 615, 10.1038/jcbfm.1994.76 Shohami, 1996, Inhibition of tumor necrosis factor α (TNFα) activity in rat brain is associated with cerebroprotection after closed head injury, J. Cereb. Blood Flow Metab., 16, 378, 10.1097/00004647-199605000-00004 Sinz, 1999, Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice, J. Clin. Invest., 104, 647, 10.1172/JCI6670 Smith, 1996, Mild pre- and post-traumatic hypothermia attenuates blood–brain barrier damage following controlled cortical impact injury in the rat, J. Neurotrauma, 13, 1, 10.1089/neu.1996.13.1 Stahel, 2000, Experimental closed head injury: analysis of neurological outcome, blood–brain barrier dysfunction, intracranial neutrophils infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines, J. Cereb. Blood Flow Metab., 20, 369, 10.1097/00004647-200002000-00019 Stover, 2001, Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-α in relation to brain edema and contusion following controlled cortical impact injury in rats, Neurosci. Lett., 288, 25, 10.1016/S0304-3940(00)01187-3 Sutcliffe, 2001, Effects of moderate hypothermia on IL-1β induced leukocyte rolling and adhesion in pial microcirculation of mice and on proinflammatory gene expression in human cerebral endothelial cells, J. Cereb. Blood Flow Metab., 21, 1310, 10.1097/00004647-200111000-00007 Taupin, 1993, Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion: Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p-site) benzodiazepine ligand, J. Neuroimmunol., 42, 177, 10.1016/0165-5728(93)90008-M Tomasevic, 1998, Changes in proliferating cell nuclear antigen, a protein involved in DNA repair in vulnerable hippocampal neurons following global cerebral ischemia, Mol. Brain Res., 60, 168, 10.1016/S0169-328X(98)00173-9 Toulmond, 1992, Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons, Neurosci. Lett., 144, 49, 10.1016/0304-3940(92)90713-H Toyoda, 1996, Intraischemic hypothermia attenuates neutrophils infiltration in the rat neocortex after focal ischemia-reperfusion injury, Neurosurgery, 39, 1200, 10.1097/00006123-199612000-00024 Truettner, 1999, Expression of brain-derived neurotrophic factor, nerve growth factor, and heat shock protein HSP70 following fluid percussion brain injury in rats, J. Neurotrauma, 16, 471, 10.1089/neu.1999.16.471 Unsicker, 2002, Functions of transforming growth factor-beta isoforms in the nervous system. Causes based on localization and experimental in vitro and in vivo evidence, Eur. J. Biochem., 267, 6972, 10.1046/j.1432-1327.2000.01824.x Vitarbo, 2004, TNF-α expression and protein levels following fluid percussion injury in rats: the effect of injury severity and brain temperature, Neurosurgery, 55, 416, 10.1227/01.NEU.0000130036.52521.2C Wick, 2001, Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta, J. Neuro-oncol., 53, 177, 10.1023/A:1012209518843 Wu, 1995, Hypothermia preserves expression of ∃-actin mRNA in ischemic brain, NeuroReport, 7, 302, 10.1097/00001756-199512290-00072 Zhou, 2001, Regulation of monocyte chemoattractant protein (MCP)-1 transcription by interferon-gamma (IFN-γ) in human astrocytoma cells: postinduction refractory state of the gene, governed by its upstream elements, FASEB J., 15, 3392, 10.1096/fj.00-0373com Zhumabayeva, 2004, Disease profiling assays: reverse format cDNA arrays complimentary to microarrays, Adv. Biochem. Eng./Biotechnol., 86, 191, 10.1007/b12443