Epidemiological investigation of fowl adenovirus infections in poultry in China during 2015–2018

Springer Science and Business Media LLC - Tập 15 - Trang 1-7 - 2019
Li Chen1, Lijuan Yin1, Qingfeng Zhou2, Peng Peng1, Yunping Du1, Linlin Liu2, Yun Zhang1, Chunyi Xue1, Yongchang Cao1
1State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
2Wen’s Foodstuffs Group Co., Ltd, Yunfu, China

Tóm tắt

Fowl adenoviruses (FAdVs) are associated with many diseases, resulting in huge economic losses to the poultry industry worldwide. Since 2015, outbreaks of FAdV infections with high mortality rates have been reported in China. A continued surveillance of FAdVs contributes to understand the epidemiology of the viruses. We isolated 155 FAdV strains from diseased chickens from poultry in China between 2015 and 2018. PCR analysis determined that 123 samples were FAdV species C, 27 were FAdV species E, and five contained two different FAdV strains. The phylogenetic analysis demonstrates that these sequences of hexon regions were clustered into three distinct serotypes: FAdV-4 (79.4%, 123/155), FAdV-8a (13.5%, 21/155) and FAdV-8b (3.9%, 6/155), of which FAdV-4 was the dominant serotype in China. The characterization of newly prevalent FAdV strains provides valuable information for the development of an effective control strategy for FAdV infections in chickens.

Tài liệu tham khảo

Harrach B, Benko M. Phylogenetic analysis of adenovirus sequences. Methods Mol Med. 2007;131:299–334. Hess M. Detection and differentiation of avian adenoviruses: a review. Avian Pathol. 2000;29:195–206. Toogood CI, Murali R, Burnett RM, Hay RT. The adenovirus type 40 hexon: sequence, predicted structure and relationship to other adenovirus hexons. J Gen Virol. 1989;70(Pt 12):3203–14. Russell WC. Adenoviruses: update on structure and function. J Gen Virol. 2009;90(Pt 1):1–20. Mase M, Mitake H, Inoue T, Imada T. Identification of group I-III avian adenovirus by PCR coupled with direct sequencing of the hexon gene. J Vet Med Sci. 2009;71:1239–42. Niczyporuk JS. Phylogenetic and geographic analysis of fowl adenovirus field strains isolated from poultry in Poland. Arch Virol. 2016;161:33–42. Schachner A, Matos M, Grafl B, Hess M. Fowl adenovirus-induced diseases and strategies for their control - a review on the current global situation. Avian Pathol. 2018;47:111–26. Grafl B, Aigner F, Liebhart D, Marek A, Prokofieva I, Bachmeier J, et al. Vertical transmission and clinical signs in broiler breeders and broilers experiencing adenoviral gizzard erosion. Avian Pathol. 2012;41:599–604. Grgic H, Philippe C, Ojkic D, Nagy E. Study of vertical transmission of fowl adenoviruses. Can J Vet Res. 2006;70:230–3. Choi KS, Kye SJ, Kim JY, Jeon WJ, Lee EK, Park KY, et al. Epidemiological investigation of outbreaks of fowl adenovirus infection in commercial chickens in Korea. Poult Sci. 2012;91:2502–6. Mase M, Nakamura K, Minami F. Fowl adenoviruses isolated from chickens with inclusion body hepatitis in Japan, 2009-2010. J Vet Med Sci. 2012;74:1087–9. Domanska-Blicharz K, Tomczyk G, Smietanka K, Kozaczynski W, Minta Z. Molecular characterization of fowl adenoviruses isolated from chickens with gizzard erosions. Poult Sci. 2011;90:983–9. Lim TH, Lee HJ, Lee DH, Lee YN, Park JK, Youn HN, et al. Identification and virulence characterization of fowl adenoviruses in Korea. Avian Dis. 2011;55:554–60. Ojkic D, Martin E, Swinton J, Vaillancourt JP, Boulianne M, Gomis S. Genotyping of Canadian isolates of fowl adenoviruses. Avian Pathol. 2008;37:95–100. Kim JN, Byun SH, Kim MJ, Kim J, Sung HW, Mo IP. Outbreaks of hydropericardium syndrome and molecular characterization of Korean fowl adenoviral isolates. Avian Dis. 2008;52:526–30. Okuda Y, Ono M, Shibata I, Sato S, Akashi H. Comparison of the polymerase chain reaction-restriction fragment length polymorphism pattern of the fiber gene and pathogenicity of serotype-1 fowl adenovirus isolates from gizzard erosions and from feces of clinically healthy chickens in Japan. J Vet Diagn Investig. 2006;18:162–7. Okuda Y, Ono M, Shibata I, Sato S. Pathogenicity of serotype 8 fowl adenovirus isolated from gizzard erosions of slaughtered broiler chickens. J Vet Med Sci. 2004;66:1561–6. Niu Y, Sun Q, Zhang G, Sun W, Liu X, Xiao Y, et al. Epidemiological investigation of outbreaks of fowl adenovirus infections in commercial chickens in China. Transbound Emerg Dis. 2018;65:e121–6. Zhang T, Jin Q, Ding P, Wang Y, Chai Y, Li Y, et al. Molecular epidemiology of hydropericardium syndrome outbreak-associated serotype 4 fowl adenovirus isolates in Central China. Virol J. 2016;13:188. O'Kane PM, Connerton IF, White KL. Pilot study of long-term anaesthesia in broiler chickens. Vet Anaesth Analg. 2016;43:72–5. Niu YJ, Sun W, Zhang GH, Qu YJ, Wang PF, Sun HL, et al. Hydropericardium syndrome outbreak caused by fowl adenovirus serotype 4 in China in 2015. J Gen Virol. 2016;97:2684–90. Ruan SF, Zhao J, Ren YC, Feng JL, Zhang GZ. Phylogenetic analyses of fowl adenoviruses (FAdV) isolated in China and pathogenicity of a FAdV-8 isolate. Avian Dis. 2017;61:353–7. Mittal D, Jindal N, Tiwari AK, Khokhar RS. Characterization of fowl adenoviruses associated with hydropericardium syndrome and inclusion body hepatitis in broiler chickens. Virus disease. 2014;25:114–9. Park HS, Lim IS, Kim SK, Kim TK, Park CK, Yeo SG. Molecular analysis of the hexon, penton base, and fiber-2 genes of Korean fowl adenovirus serotype 4 isolates from hydropericardium syndrome-affected chickens. Virus Genes. 2017;53:111–6. Joubert HW, Aitchison H, Maartens LH, Venter EH. Molecular differentiation and pathogenicity of Aviadenoviruses isolated during an outbreak of inclusion body hepatitis in South Africa. J S Afr Vet Assoc. 2014;85:1058. Maartens LH, Joubert HW, Aitchison H, Venter EH. Inclusion body hepatitis associated with an outbreak of fowl adenovirus type 2 and type 8b in broiler flocks in South Africa. J S Afr Vet Assoc. 2014;85:e1–5. Kajan GL, Kecskemeti S, Harrach B, Benko M. Molecular typing of fowl adenoviruses, isolated in Hungary recently, reveals high diversity. Vet Microbiol. 2013;167:357–63. Schachner A, Marek A, Grafl B, Hess M. Detailed molecular analyses of the hexon loop-1 and fibers of fowl aviadenoviruses reveal new insights into the antigenic relationship and confirm that specific genotypes are involved in field outbreaks of inclusion body hepatitis. Vet Microbiol. 2016;186:13–20. Naeem K, Niazi T, Malik SA, Cheema AH. Immunosuppressive potential and pathogenicity of an avian adenovirus isolate involved in hydropericardium syndrome in broilers. Avian Dis. 1995;39:723–8. Afzal M, Muneer R, Stein G. Studies on the aetiology of hydropericardium syndrome (Angara disease) in broilers. Vet Rec. 1991;128:591–3. Changjing L, Haiying L, Dongdong W, Jingjing W, Youming W, Shouchun W, et al. Characterization of fowl adenoviruses isolated between 2007 and 2014 in China. Vet Microbiol. 2016;197:62–7.