Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial

The Lancet - Tập 391 - Trang 748-757 - 2018
Thomas Powles1, Ignacio Durán2,3, Michiel S van der Heijden4, Yohann Loriot5, Nicholas J Vogelzang6, Ugo De Giorgi7, Stéphane Oudard8, Margitta M Retz9, Daniel Castellano10, Aristotelis Bamias11, Aude Fléchon12, Gwenaëlle Gravis13, Syed Hussain14, Toshimi Takano, Ning Leng15, Edward E Kadel15, Romain Banchereau15, Priti S Hegde15, Sanjeev Mariathasan15, Na Cui15
1Barts Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London, St Bartholomew's Hospital, London, UK
2Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
3Institute of Biomedicine of Seville, Seville, Spain
4Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands
5Département de Médecine Oncologique, Université Paris-Saclay, Gustave Roussy, Villejuif, France
6US Oncology Research, Comprehensive Cancer Centers of Nevada, Las Vegas, NV, USA
7Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy
8Oncology Department, European Georges Pompidou Hospital, René Descartes University, Paris, France
9Department of Urology, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany
10University Hospital 12 de Octubre, Medical Oncology Department CIBER-ONC, Madrid, Spain
11National and Kapodistrian University of Athens Alexandra Hospital, Athens, Greece
12Centre Léon-Bérard, Lyon, France
13Department of Cancer Medicine, Institut Paoli Calmette, Marseille, France
14Plymouth University, Peninsula Schools of Medicine and Dentistry, Plymouth University Hospitals NHS Trust, Plymouth, UK
15Genentech, South San Francisco, CA, USA

Tài liệu tham khảo

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