Cardiac death after breast radiotherapy and the QUANTEC cardiac guidelines

Darby, 2011, Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials, Lancet (London, England), 378, 1707, 10.1016/S0140-6736(11)61629-2 Early Breast Cancer Trialists' Collaborative G, 2014, Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials, Lancet, 383, 2127, 10.1016/S0140-6736(14)60488-8 Cuzick, 1994, Cause-specific mortality in long-term survivors of breast cancer who participated in trials of radiotherapy, J Clin Oncol, 12, 447, 10.1200/JCO.1994.12.3.447 Paszat, 1999, Mortality from myocardial infarction following postlumpectomy radiotherapy for breast cancer: a population-based study in Ontario, Canada, Int J Radiat Oncol Bio Phys, 43, 755, 10.1016/S0360-3016(98)00412-X Darby, 2005, Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer: prospective cohort study of about 300,000 women in US SEER cancer registries, Lancet Oncol, 6, 557, 10.1016/S1470-2045(05)70251-5 Darby, 2013, Risk of ischemic heart disease in women after radiotherapy for breast cancer, N Engl J Med, 368, 987, 10.1056/NEJMoa1209825 Taylor, 2017, Estimating the risks of breast cancer radiotherapy: evidence from modern radiation doses to the lungs and heart and from previous randomized trials, J Clin Oncol, 35, 1641, 10.1200/JCO.2016.72.0722 Merzenich, 2017, 3D conformal radiotherapy is not associated with the long-term cardiac mortality in breast cancer patients: a retrospective cohort study in Germany (PASSOS-Heart Study), Breast Cancer Res Treat, 161, 143, 10.1007/s10549-016-4042-2 Taylor, 2007, Cardiac exposures in breast cancer radiotherapy: 1950s–1990s, Int J Radiat Oncol Biol Phys, 69, 1484, 10.1016/j.ijrobp.2007.05.034 Taylor, 2008, Cardiac dose from tangential breast cancer radiotherapy in the year 2006, Int J Radiat Oncol Biol Phys, 72, 501, 10.1016/j.ijrobp.2007.12.058 McGale, 2011, Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden, Radiother Oncol, 100, 167, 10.1016/j.radonc.2011.06.016 Feng, 2011, Development and validation of a heart atlas to study cardiac exposure to radiation following treatment for breast cancer, Int J Radiat Oncol Biol Phys, 79, 10, 10.1016/j.ijrobp.2009.10.058 Duane, 2017, A cardiac contouring atlas for radiotherapy, Radiother Oncol, 122, 416, 10.1016/j.radonc.2017.01.008 Lee, 2017, Development of delineation for the left anterior descending coronary artery region in left breast cancer radiotherapy: an optimized organ at risk, Radiother Oncol, 122, 423, 10.1016/j.radonc.2016.12.029 Gagliardi, 2010, Radiation dose-volume effects in the heart, Int J Radiat Oncol Biol Phys, 76, S77, 10.1016/j.ijrobp.2009.04.093 Nilsson, 2012, Distribution of coronary artery stenosis after radiation for breast cancer, J Clin Oncol, 30, 380, 10.1200/JCO.2011.34.5900 Hooning, 2007, Long-term risk of cardiovascular disease in 10-year survivors of breast cancer, J Natl Cancer Inst, 99, 365, 10.1093/jnci/djk064 Harris, 2006, Late cardiac mortality and morbidity in early-stage breast cancer patients after breast-conservation treatment, J Clin Oncol, 24, 4100, 10.1200/JCO.2005.05.1037 Jones, 2001, The role of biologically effective dose (BED) in clinical oncology, Clin Oncol (Royal College of Radiologists (Great Britain)), 13, 71 Clarke, 2005, Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials, Lancet (London, England), 366, 2087, 10.1016/S0140-6736(05)67887-7 Rutqvist, 1998, Myocardial infarction among women with early-stage breast cancer treated with conservative surgery and breast irradiation, Int J Radiat Oncol Biol Phys, 40, 359, 10.1016/S0360-3016(97)00765-7 Nixon, 1998, No long-term increase in cardiac-related mortality after breast-conserving surgery and radiation therapy using modern techniques, J Clin Oncol, 16, 1374, 10.1200/JCO.1998.16.4.1374 Vallis, 2002, Assessment of coronary heart disease morbidity and mortality after radiation therapy for early breast cancer, J Clin Oncol, 20, 1036, 10.1200/JCO.2002.20.4.1036 Doyle, 2007, Radiation therapy, cardiac risk factors, and cardiac toxicity in early-stage breast cancer patients, Int J Radiat Oncol Biol Phys, 68, 82, 10.1016/j.ijrobp.2006.12.019 Taylor, 2009, Cardiac doses from Swedish breast cancer radiotherapy since the 1950s, Radiother Oncol, 90, 127, 10.1016/j.radonc.2008.09.029 Simonetto, 2018, Does deep inspiration breath-hold prolong life? Individual risk estimates of ischaemic heart disease after breast cancer radiotherapy, Radiother Oncol Giordano, 2005, Risk of cardiac death after adjuvant radiotherapy for breast cancer, J Natl Cancer Inst, 97, 419, 10.1093/jnci/dji067 Drost, 2018, A systematic review of heart dose in breast radiotherapy, Clin Breast Cancer, 18, e819, 10.1016/j.clbc.2018.05.010 Krueger, 2004, Cardiac chamber and coronary artery doses associated with postmastectomy radiotherapy techniques to the chest wall and regional nodes, Int J Radiat Oncol Biol Phys, 60, 1195, 10.1016/j.ijrobp.2004.04.026 Correa, 2007, Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancer, J Clin Oncol, 25, 3031, 10.1200/JCO.2006.08.6595 van den Bogaard, 2017, Validation and modification of a prediction model for acute cardiac events in patients with breast cancer treated with radiotherapy based on three-dimensional dose distributions to cardiac substructures, J Clin Oncol, 35, 1171, 10.1200/JCO.2016.69.8480 Taylor, 2018, Cardiac structure injury after radiotherapy for breast cancer: cross-sectional study with individual patient data, J Clin Oncol, 36, 2288, 10.1200/JCO.2017.77.6351 Marks, 2005, The incidence and functional consequences of RT-associated cardiac perfusion defects, Int J Radiat Oncol Biol Phys, 63, 214, 10.1016/j.ijrobp.2005.01.029 Marks, 2017, Reassessing the time course for radiation-induced cardiac mortality in patients with breast cancer, Int J Radiat Oncol Biol Phys, 97, 303, 10.1016/j.ijrobp.2016.10.036 Paszat, 1998, Mortality from myocardial infarction after adjuvant radiotherapy for breast cancer in the surveillance, epidemiology, and end-results cancer registries, J Clin Oncol, 16, 2625, 10.1200/JCO.1998.16.8.2625