Implementation of an Interferon-Gamma Release Assay to Screen for Tuberculosis in Refugees and Immigrants

Springer Science and Business Media LLC - Tập 15 - Trang 686-692 - 2012
Terri Simpson1, Julie Tomaro2, Cynthia Jobb3
1University of Washington School of Nursing, Seattle, USA
2Washington State Department of Health, Olympia, USA
3Spokane, USA

Tóm tắt

Despite increased use and accuracy of interferon-gamma release assays to detect latent tuberculosis infection (LTBI) in foreign-born arrivals in the United States, risk characteristics associated with positive results are not well characterized. We conducted a retrospective record review of 541 refugees and immigrants screened for LTBI with QuantiFERON®-TB Gold In-Tube (QFT-IT) at the Spokane Public Health Clinic from January 2, 2008, through June 5, 2009. Overall, 24 % of the arrivals had a positive QFT-IT, with the greatest frequency of positive results occurring in arrivals from Liberia (100 %) and Bhutan (39 %). More than the expected number of Burmese had indeterminate QFT-IT results. A positive QFT-IT was associated with age, race, ethnicity, and extent of TB burden in the country of origin. QFT-IT is useful to screen for LTBI in foreign-born arrivals, particularly middle-aged adults from high-burden countries. However, the QFT-IT may not yield meaningful results in groups with significant immunocompromise.

Tài liệu tham khảo

Ricks PM, Cain KP, Oeltmann JE, Kammerer JS, Moonan PK. Estimating the burden of tuberculosis among foreign-born persons acquired prior to entering the US, 2005–2009. PLoS ONE 2011;6(11):e27405. Available from: http://www.plosone.org/article/citationList.action;jsessionid=2320E03AEF5A68291028BDBA0B53654F?articleURI=info%3Adoi%2F10.1371%2Fjournal.pone.0027405. Accessed 18 Jan 2012. Cain KP, Haley CA, Armstrong LR, Garman KN, Wells CD, Iademarco MF, Castro KG, Laserson KF. Tuberculosis among foreign-born persons in the United States. Am J Respir Crit Care Med. 2007;175(1):75–9. Taylor Z, Nolan CM, Blumberg HM. Controlling tuberculosis in the United States. MMWR Recomm Rep 2005;54(RR-12):1–81. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5412a1.htm. Accessed 18 Jan 2012. Centers for Disease Control. Reported Tuberculosis in the United States, 2010. US Department of Health and Human Services, CDC, Atlanta, Oct 2011. Available from http://www.cdc.gov/tb/statistics/reports/2010/. Accessed 18 Jan 2012. Moreno S, Blázquez R, Novoa A, Carpena I, Menasalvas A, Ramírez C, Guerrero C. The effect of BCG vaccination on tuberculin reactivity and the booster effect among hospital employees. Arch Intern Med. 2001;161(14):1760–5. Weinfurter P, Blumberg HM, Goldbaum G, Royce R, Pang J, Tapia J, Bethel J, Mazurek GH, Toney S, Albalak R. Predictors of discordant tuberculin skin test and QuantiFERON®-TB Gold In-Tube results in various high-risk groups. Int J Tuberc Lung Dis. 2011;15(8):1056–61. Orlando G, Merli S, Cordier L, Mazza F, Casazza G, Villa AM, Codecasa L, Negri E, Carguel A, Ferrarese M, Rizzardini G. Interferon-γ releasing assay versus tuberculin skin testing for latent tuberculosis infection in targeted screening programs for high risk immigrants. Infection. 2010;38(3):195–204. Grinsdale JA, Ho CS, Banouvong H, Kawamura LM. Programmatic impact of using QuantiFERON®-TB gold in routine contact investigation activities. Int J Tuberc Lung Dis. 2011;15(12):1614–20. Linas BP, Wong AY, Freedberg KA, Horsburgh CR. Priorities for screening and treatment of latent tuberculosis infection in the United States. Am J Respir Crit Care Med. 2011;184(5):590–601. Mazurek GH, Jereb J, Vernon A, LoBue P, Goldberg S, Castro K. Updated guidelines for using interferon gamma release assays to detect Mycobacterium tuberculosis infection: United States, 2010. MMWR Recomm Rep 2010;59(RR-5):1–25. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5905a1.htm. Accessed 19 Jan 2012. Diel R, Loddenkemper R, Nienhaus A. Evidence-based comparison of commercial interferon-γ release assays for detecting active TB: a metaanalysis. Chest. 2010;137(4):952–68. Pai M, Zwerling A, Menzies D. Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Ann Intern Med. 2008;149(3):177–84. Walters NP, Trevelyan EN. The newly arrived foreign-born population of the United States: 2010. US Census Bureau. Nov 2011. Available from: http://www.census.gov/prod/2011pubs/acsbr10-16.pdf. Accessed 19 Jan 2012. Spokane Regional Health District. Refugee Program Manual. Washington State Department of Health 343-NonDOH. Jul 2011. Available from: http://www.doh.wa.gov/YouandYourFamily/IllnessandDisease/Tuberculosis/ProviderMaterials.aspx. Accessed 16 Jul 2012. US Immigration Department. Data standards and definitions. 2011. Available from http://www.dhs.gov/files/statistics/dtadefstd.shtm. Accessed 20 Jan 2012. Centers for Disease Control and Prevention. Guidelines for using the QuantiFERON-TB Gold Test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005;54(RR15):49–55. Available from http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5415a4.htm. Accessed 20 Jan 2012. Simpson T, Fox J, Crouse K, Field K. Screening for Mycobacterium tuberculosis using an interferon-gamma release assay. J Pub Health Manag Pract. 2012;18(4):E19–25. Andersen P, Munk ME, Pollock JM, Doherty TM. Specific immune-based diagnosis of tuberculosis. Lancet. 2000;356(9235):1099–104. World Health Organization. WHO Report 2011. Global Tuberculosis Control. World Health Organization. 2011. Available from http://www.who.int/tb/publications/global_report/en/. Accessed 12 Jul 2012. Dewan PK, Grinsdale J, Liska S, Wong E, Fallstad R, Kawamura LM. Feasibility, acceptability, and cost of tuberculosis testing by whole-blood interferon-gamma assay. BMC Inf Dis. 2006;15(6):47. Harstad I, Winje BA, Heidal E, Oftung F, Jacobsen GWl. Predictive values of QuantiFERON®-TB Gold testing in screening for tuberculosis disease in asylum seekers. Int J Tuberc Lung Dis. 2010;14(9):1209–11. Chaves NJ, Gibney KB, Leder K, O’Brien DP, Marshall C, Biggs BA. Screening practices for infectious diseases among Burmese refugees in Australia. Emerg Inf Dis. 2009;15(11):1769–72. Denburg A, Rashid M, Brophy J, Curtis T, Malloy P, Audley J, Pegg W, Hoffman S, Banerji A. Initial health screening results for Karen refugees: a retrospective review. Can Comm Dis Rep. 2007;33(13):16–22. Power DV, Moody E, Trussell K, O’Fallon A, Chute S, Kyaw M, Letts J, Mamo Bl. Caring for the Karen: a newly arrived refugee group. Minn Med. 2010;93(4):49–53. Centers for Disease Control and Prevention. Promoting Cultural Sensitivity: a Practical Guide for Tuberculosis Programs that Provide Services to Persons from Burma. 2010. Available from: http://www.cdc.gov/tb/publications/guidestoolkits/EthnographicGuides/Burma/default.htm. Accessed 12 Jul 2012. Office of Immigration Statistics. 2010 Yearbook of Immigration Statistics. U.S. Department of Homeland Security. 2011. Available from: http://www.dhs.gov/xlibrary/assets/statistics/yearbook/2010/ois_yb_2010.pdf. Accessed 13 Jul 2012. Washington State Report. Individual refugee arrivals Washington State October 2009 through April 2010. Available from: http://www.seattle.gov/humanservices/lifelines/201007RefugeeArrivalsReport.pdf. Accessed 22 Jun 2012. Winje BA, Oftung F, Korsvold GE, Mannsåker T, Jeppesen AS, Harstad I, Heier BT, Heldal E. Screening for tuberculosis infection among newly arrived asylum seekers: Comparison of QuantiFERON®TB Gold with tuberculin skin test. BMC Inf Dis. 2008 May 14. 8(65);1–10. Available from: http://www.biomedcentral.com/1471-2334/8/65. Accessed 13 Jul 2012. Powell RD, Whitworth WC, Bernardo J, Moonan PK, Mazurek GH. Unusual interferon gamma measurements with QuantiFERON-TB Gold and QuantiFERON-TB Gold In-Tube tests. PLoS ONE 2011;6(6):e20061. Available from: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0020061. Accessed 16 Jul 2012. Simpson T, Fox J, Crouse K, Field K. Quantitative and qualitative QuantiFERON-TB Gold In-Tube results among groups with varying risk of exposure to tuberculosis. Heart Lung 2012;41(6):553–61. Dasgupta K, Menzies D. Cost-effectiveness of tuberculosis control strategies among immigrants and refugees. Eur Respir J. 2005;25(6):1107–16.