Antioxidant properties of calcium antagonists related to membrane biophysical interactions

Janis, 1987, Drug action and calcium regulation, Adv Drug Res, 16, 309 Janero, 1988, Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists, Biochem Pharmacol, 37, 4197, 10.1016/0006-2952(88)90116-5 Ondrias, 1989, Lipid peroxidation of phosphatidylcholine liposomes depressed by the calcium channel blockers nifedipine and verapamil and by the antiarrhythmic-antihypoxic drug stobadine, Biochim Biophys Acta, 1003, 238, 10.1016/0005-2760(89)90228-2 Mak, 1990, Comparative antioxidant activities of propranolol, nifedipine, verapamil, and diltiazem against sarcolemmal membrane lipid peroxidation, Circ Res, 66, 1449, 10.1161/01.RES.66.5.1449 Mak, 1992, Antioxidant properties of active and inactive isomers of nicardipine in cardiac membranes, endothelial cells, and perfused rat hearts, Coron Artery Dis, 3, 1095, 10.1097/00019501-199211000-00013 Ross, 1986, The pathogenesis of atherosclerosis, Nature, 362, 801, 10.1038/362801a0 Lichtlen, 1990, Retardation of coronary artery disease in humans by the calcium-channel blocker nifedipine, Cardiovasc Drugs Ther, 4, S1047, 10.1007/BF02018315 Keogh, 1990, A review of calcium antagonists and atherosclerosis, J Cardiovasc Pharmacol, 16, S28, 10.1097/00005344-199000006-00007 Henry PD. Antiperoxidative actions of calcium antagonists and atherogenesis. J Cardiovasc Pharmacol 1991;18:S6–S10. Steinberg, 1991, Antioxidants and atherosclerosis, Circulation, 84, 1420, 10.1161/01.CIR.84.3.1420 Janero, 1989, Antiperoxidant effects of dihydropyridine calcium antagonists, Biochem Pharmacol, 38, 4344, 10.1016/0006-2952(89)90537-6 Mak, 1992, Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells, Circ Res, 70, 1099, 10.1161/01.RES.70.6.1099 Mason, 1989, Comparison of location and binding for the positively charged 1,4-dihydropyridine calcium channel antagonist amlodipine with uncharged drugs of this class in cardiac membranes, Mol Pharmacol, 36, 634 Mason, 1992, Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer, Mol Pharmacol, 41, 315 May, 1968, Reduced triphosphopyridine nucleotide oxidase-catalyzed alterations of membrane phospholipids, J Biol Chem, 243, 2296, 10.1016/S0021-9258(18)93475-7 Mak, 1983, Temporal relationship of free radical-induced lipid peroxidation and loss of latent enzyme activity in highly enriched hepatic lysosomes, J Biol Chem, 258, 13733, 10.1016/S0021-9258(17)43979-2 Bangham, 1965, Diffusion of univalent ions across the lamellae of swollen phospholipids, J Mol Biol, 13, 238, 10.1016/S0022-2836(65)80093-6 Herbette, 1985, The separate profile structures of the functional Ca2+ and the phospholipid bilayer within isolated sarcoplasmic reticulum, Biophys J, 20, 245, 10.1016/S0006-3495(77)85547-1 Moody, 1963, X-ray diffraction pattern of nerve myelin, Science, 142, 1173, 10.1126/science.142.3596.1173 Jain, 1977, Effect of small molecules on the dipalmitoyl lecithin liposomal bilayer, J Membr Biol, 34, 157, 10.1007/BF01870299 Bauerle, 1991, Interaction of charged and uncharged calcium channel antagonists with phospholipid membranes, Biochem J, 30, 7203, 10.1021/bi00243a023 Packer, 1996, Effect of amlodipine on morbidity and mortality in severe chronic heart failure, N Engl J Med, 335, 1107, 10.1056/NEJM199610103351504 Byington, 1999, Effect of amlodipine on cardiovascular events and procedures, J Am Coll Cardiol, 33, 314A Mason, 1999, Membrane antioxidant effects of the charged dihydropyridine calcium antagonist amlodipine, J Mol Cell Cardiol, 31, 275, 10.1006/jmcc.1998.0867