Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain

Brain, Behavior, and Immunity - Tập 42 - Trang 169-177 - 2014
Yohance M. Allette1, Michael R. Due2, Sarah M. Wilson3, Polina Feldman3, Matthew S. Ripsch2, Rajesh Khanna4,5,3, Fletcher A. White2,3
1Medical Science Training Program, Department of Anatomy, Indiana University School of Medicine, Indianapolis, IN, United States
2Department of Anesthesia, Indiana University School of Medicine, Indianapolis, IN, United States
3Program in Medical Neurosciences, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, United States
4Department of Biochemistry and Molecular Biology, United States
5Department of Pharmacology and Toxicology, United States

Tóm tắt

Từ khóa


Tài liệu tham khảo

Akirav, 2012, RAGE expression in human T cells: a link between environmental factors and adaptive immune responses, PLoS One, 7, e34698, 10.1371/journal.pone.0034698

Andersson, 2011, HMGB1 is a therapeutic target for sterile inflammation and infection, Annu Rev Immunol, 29, 139, 10.1146/annurev-immunol-030409-101323

Antoine, 2010, Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity, Mol Med, 16, 479, 10.2119/molmed.2010.00126

Bevan, 2010, Selection, preparation, and evaluation of small- molecule inhibitors of toll-like receptor 4, ACS Med Chem Lett, 1, 194, 10.1021/ml100041f

Bhangoo, 2007, Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors, Mol Pain, 3, 38, 10.1186/1744-8069-3-38

Bianchi, 2007, DAMPs, PAMPs and alarmins: all we need to know about danger, J Leukoc Biol, 81, 1, 10.1189/jlb.0306164

Bianchi, 1992, The DNA binding site of HMG1 protein is composed of two similar segments (HMG boxes), both of which have counterparts in other eukaryotic regulatory proteins, EMBO J, 11, 1055, 10.1002/j.1460-2075.1992.tb05144.x

Calvo, 2012, The role of the immune system in the generation of neuropathic pain, Lancet Neurol, 11, 629, 10.1016/S1474-4422(12)70134-5

Campana, 2009, Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells, J Leukoc Biol, 86, 609, 10.1189/jlb.0908576

Chacur, 2001, A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats, Pain, 94, 231, 10.1016/S0304-3959(01)00354-2

Cheng K, Wang X, Zhang S, Yin H. Discovery of Small-Molecule Inhibitors of the TLR1/TLR2 Complex. Angew Chem Int Ed Engl. 2012.

Czura, 2001, Dual roles for HMGB1: DNA binding and cytokine, J Endotoxin Res, 7, 315, 10.1177/09680519010070041401

Diogenes A, Ferraz CC, Akopian AN, Henry MA, Hargreaves KM. LPS Sensitizes TRPV1 via Activation of TLR4 in Trigeminal Sensory Neurons. J Dent Res. 2011;Jun;90(6):759–64.

Due, 2012, Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling, J Neuroinflammation, 9, 200, 10.1186/1742-2094-9-200

Dumitriu, 2005, HMGB1: guiding immunity from within, Trends Immunol, 26, 381, 10.1016/j.it.2005.04.009

Fages, 2000, Regulation of cell migration by amphoterin, J Cell Sci, 113, 611, 10.1242/jcs.113.4.611

Feldman, 2012, The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain, J Neuroinflammation, 9, 180, 10.1186/1742-2094-9-180

Giese, 1992, The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures, Cell, 69, 185, 10.1016/0092-8674(92)90129-Z

Guo J, Hsieh C, Wu Z, DiGiammarino EL, Luo F, Fox GB, et al. Antibodies to receptor of advanced glycation end products (RAGE) and uses thereof. In: Office USPaT, editor. United States: Abbott Laboratories, Abbott Park, IL Abbott GMbH & Co. KG, Wiesbaden-Delkenheim, DE; 2012.

Hoppe, 2006, Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1, Exp Cell Res, 312, 3526, 10.1016/j.yexcr.2006.07.020

Hori, 1995, The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system, J Biol Chem, 270, 25752, 10.1074/jbc.270.43.25752

Hreggvidsdottir, 2012, High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor, Mol Med, 18, 224, 10.2119/molmed.2011.00327

Hua, 1996, Involvement of cytokines in lipopolysaccharide-induced facilitation of CGRP release from capsaicin-sensitive nerves in the trachea: studies with interleukin-1beta and tumor necrosis factor-alpha, J Neurosci, 16, 4742, 10.1523/JNEUROSCI.16-15-04742.1996

Huttunen, 2002, Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis, Cancer Res, 62, 4805

Iori, 2013, Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures, Neurobiol Dis, 58, 102, 10.1016/j.nbd.2013.03.006

Karatas, 2013, Spreading depression triggers headache by activating neuronal Panx1 channels, Science, 339, 1092, 10.1126/science.1231897

Kazama, 2008, Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein, Immunity, 29, 21, 10.1016/j.immuni.2008.05.013

Ma, 2005, Enhanced excitability of dissociated primary sensory neurons after chronic compression of the dorsal root ganglion in the rat, Pain, 113, 106, 10.1016/j.pain.2004.10.001

Maroso, 2010, Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures, Nat Med, 16, 413, 10.1038/nm.2127

Merenmies, 1991, 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane, J Biol Chem, 266, 16722, 10.1016/S0021-9258(18)55361-8

Nakamura, 2013, Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1, PLoS One, 8, e73640, 10.1371/journal.pone.0073640

Ochoa-Cortes, 2010, Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons, Am J Physiol Gastrointest Liver Physiol, 299, 723, 10.1152/ajpgi.00494.2009

O’Connor KA, Hansen MK, Rachal Pugh C, Deak MM, Biedenkapp JC, Milligan ED, et al. Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine. 2003;24:254–65.

Otoshi K, Kikuchi S, Kato K, Sekiguchi M, Konno S, et et al. Anti-HMGB1 neutralization antibody improves pain-related behavior induced by application of autologous nucleus pulposus onto nerve roots in rats. Spine (Phila Pa 1976). 2011;36:E692–8.

Parkkinen, 1993, Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation, J Biol Chem, 268, 19726, 10.1016/S0021-9258(19)36575-5

Qiu, 2010, High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia, Stroke, 41, 2077, 10.1161/STROKEAHA.110.590463

Rauvala, 1987, Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons, J Biol Chem, 262, 16625, 10.1016/S0021-9258(18)49302-7

Rong, 2004, Antagonism of RAGE suppresses peripheral nerve regeneration, FASEB J, 18, 1812, 10.1096/fj.04-1899com

Rong, 2004, RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways, FASEB J, 18, 1818, 10.1096/fj.04-1900com

Rouhiainen, 2004, Regulation of monocyte migration by amphoterin (HMGB1), Blood, 104, 1174, 10.1182/blood-2003-10-3536

Rouhiainen, 2013, RAGE-Mediated Cell Signaling, Methods Mol Biol, 963, 239, 10.1007/978-1-62703-230-8_15

Sahu, 2008, Redox properties of the A-domain of the HMGB1 protein, FEBS Lett, 582, 3973, 10.1016/j.febslet.2008.09.061

Sha, 2008, HMGB1 develops enhanced proinflammatory activity by binding to cytokines, J Immunol, 180, 2531, 10.4049/jimmunol.180.4.2531

Shibasaki, 2010, Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury, Pain, 149, 514, 10.1016/j.pain.2010.03.023

Strakhova MI, Desiree-Brederson J. Antibodies to receptor of advanced glycation end products (RAGE) and uses thereof. In: Office USPaT, editor. United States: Abbvie Inc., North Chicago, IL 2013.

Ulloa, 2005, The “cytokine profile”: a code for sepsis, Trends Mol Med, 11, 56, 10.1016/j.molmed.2004.12.007

Venereau, 2013, HMGB1 and leukocyte migration during trauma and sterile inflammation, Mol Immunol, 55, 76, 10.1016/j.molimm.2012.10.037

Vezzoli, 2010, Redox remodeling: a candidate regulator of HMGB1 function in injured skeletal muscle, Ann N Y Acad Sci, 1209, 83, 10.1111/j.1749-6632.2010.05748.x

Vezzoli, 2011, High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscle, Antioxid Redox Signal, 15, 2161, 10.1089/ars.2010.3341

White, 2005, Chemokines: integrators of pain and inflammation, Nat Rev Drug Discov, 4, 834, 10.1038/nrd1852

Yang, 2010, A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release, Proc Natl Acad Sci U S A, 107, 11942, 10.1073/pnas.1003893107

Yang, 2011, HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signaling, J Cereb Blood Flow Metab, 31, 593, 10.1038/jcbfm.2010.129

Yang, 2012, Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1), Mol Med, 18, 250, 10.2119/molmed.2011.00389

Zandarashvili, 2013, Real-time kinetics of high-mobility group box 1 (HMGB1) oxidation in extracellular fluids studied by in situ protein NMR spectroscopy, J Biol Chem, 288, 11621, 10.1074/jbc.M113.449942

Zhang, 1999, Enhanced excitability of sensory neurons in rats with cutaneous hyperalgesia produced by chronic compression of the dorsal root ganglion, J Neurophysiol, 82, 3359, 10.1152/jn.1999.82.6.3359

Zhang, 2011, Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats, Stroke, 42, 1420, 10.1161/STROKEAHA.110.598334