A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
Karen Julie la Cour Karottki1, Hooman Hefzi2,3,4, Songyuan Li1, Lasse Ebdrup Pedersen1, Philipp N. Spahn2,3, Chintan Joshi2,3, David Ruckerbauer5,6, Juan A.Hernandez Bort5, Alex Thomas2, Jae Seong Lee7, Nicole Borth5,6, Gyun Min Lee8, Helene Faustrup Kildegaard1, Nathan E. Lewis2,3,4,9
1The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Denmark
2The Novo Nordisk Foundation Center for Biosustainability at the University of California, San Diego, USA
3Department of Pediatrics, University of California, San Diego, USA
4Department of Bioengineering, University of California, San Diego, USA
5Austrian Centre of Industrial Biotechnology, Vienna, Austria
6University of Natural Resources and Life Sciences Vienna, Austria
7Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea
8Department of Biological Sciences, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea
9National Biologics Facility, Technical University of Denmark, Denmark
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Metabolic Engineering
Tập 66
114-122
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