Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
Pingping Li1,2,3, Shuainan Liu1,2, Min Lu3,4, Gautum Bandyopadhyay3, Dayoung Oh3, Takeshi Imamura5, Andrew M.F. Johnson3, Dorothy Sears3, Zhufang Shen1,2, Bing Cui1,2, Lijuan Kong1,2, Shaocong Hou1,2, Xiao Liang1,2, Salvatore Iovino4, Steven M. Watkins6, Wei Ying3, Olivia Osborn3, Joshua Wollam3, Martin Brenner4, Jerrold M. Olefsky3
1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China
2Diabetes Research Center of Chinese Academy of Medical Sciences, Beijing 100050, China
3Division of Endocrinology and Metabolism, UC, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
4Diabetes Early Discovery, Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115, USA
5Pharmacology, Department of Medicine, Shiga University of Medical Science, 1 Tsukinowa, Seta, Otsu-city, Shiga 520-2192, Japan
6Lipomics Technologies, Inc., West Sacramento, CA 95691, USA