Lesion of the rostral anterior cingulate cortex eliminates the aversiveness of spontaneous neuropathic pain following partial or complete axotomy

Abdulla, 2001, Axotomy- and autotomy-induced changes in Ca2 and K channel currents of rat dorsal root ganglion neurons., J Neurophysiol, 85, 644, 10.1152/jn.2001.85.2.644 Apkarian, 2005, Human brain mechanisms of pain perception and regulation in health and disease., Eur J Pain, 9, 463, 10.1016/j.ejpain.2004.11.001 Burgess, 2002, Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain., J Neurosci, 22, 5129, 10.1523/JNEUROSCI.22-12-05129.2002 Bush, 2000, Cognitive and emotional influences in anterior cingulate cortex., Trends Cogn Sci, 4, 215, 10.1016/S1364-6613(00)01483-2 Campbell, 2006, Mechanisms of neuropathic pain., Neuron, 52, 77, 10.1016/j.neuron.2006.09.021 Casey, 1999, Forebrain mechanisms of nociception and pain: analysis through imaging., Proc Natl Acad Sci USA, 96, 7668, 10.1073/pnas.96.14.7668 Casey, 1996, Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain., J Neurophysiol, 76, 571, 10.1152/jn.1996.76.1.571 Casey, 2001, Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomography., J Neurophysiol, 85, 951, 10.1152/jn.2001.85.2.951 Chaplan, 1994, Quantitative assessment of tactile allodynia in the rat paw., J Neurosci Methods, 53, 55, 10.1016/0165-0270(94)90144-9 Craig, 1996, Functional imaging of an illusion of pain., Nature, 384, 258, 10.1038/384258a0 Devinsky, 1995, Contributions of anterior cingulate cortex to behaviour., Brain, 118, 279, 10.1093/brain/118.1.279 Devor, 1991, Sensory basis of autotomy in rats., Pain, 45, 109, 10.1016/0304-3959(91)90174-V Devor, 2001, Neuropathic pain: what do we do with all these theories?, Acta Anaesthesiol Scand, 45, 1121, 10.1034/j.1399-6576.2001.450912.x Devor, 2006, Sodium channels and mechanisms of neuropathic pain., J Pain, 7, S3, 10.1016/j.jpain.2005.09.006 Devor, 2009, Ectopic discharge in Abeta afferents as a source of neuropathic pain., Exp Brain Res, 196, 115, 10.1007/s00221-009-1724-6 Dixon, 1980, Efficient analysis of experimental observations., Annu Rev Pharmacol Toxicol, 20, 441, 10.1146/annurev.pa.20.040180.002301 Donahue, 2001, Electrolytic lesion of the anterior cingulate cortex decreases inflammatory, but not neuropathic nociceptive behavior in rats., Brain Res, 897, 131, 10.1016/S0006-8993(01)02103-5 Ducreux, 2006, Mechanisms of central neuropathic pain: a combined psychophysical and fMRI study in syringomyelia., Brain, 129, 963, 10.1093/brain/awl016 Foltz, 1962, Pain relief by frontal cingulumotomy., J Neurosurg, 19, 89, 10.3171/jns.1962.19.2.0089 Govrin-Lippmann, 1978, Ongoing activity in severed nerves: source and variation with time., Brain Res, 159, 406, 10.1016/0006-8993(78)90548-6 Gracely, 1992, Painful neuropathy: altered central processing maintained dynamically by peripheral input., Pain, 51, 175, 10.1016/0304-3959(92)90259-E Hsieh, 1995, Central representation of chronic ongoing neuropathic pain studied by positron emission tomography., Pain, 63, 225, 10.1016/0304-3959(95)00048-W Hurt, 1974, Stereotactic anterior cingulate lesions for persistent pain: a report on 68 cases., Clin Neurosurg, 21, 334, 10.1093/neurosurgery/21.CN_suppl_1.334 Hutchison, 1999, Pain-related neurons in the human cingulate cortex., Nat Neurosci, 2, 403, 10.1038/8065 Johansen, 2004, Glutamatergic activation of anterior cingulate cortex produces an aversive teaching signal., Nat Neurosci, 7, 398, 10.1038/nn1207 Johansen, 2001, The affective component of pain in rodents: direct evidence for a contribution of the anterior cingulate cortex., Proc Natl Acad Sci USA, 98, 8077, 10.1073/pnas.141218998 Kim, 1992, An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat., Pain, 50, 355, 10.1016/0304-3959(92)90041-9 King, 2009, Unmasking the tonic-aversive state in neuropathic pain., Nat Neurosci, 12, 1364, 10.1038/nn.2407 Koyama, 2000, During pain-avoidance neurons activated in the macaque anterior cingulate and caudate., Neurosci Lett, 283, 17, 10.1016/S0304-3940(00)00894-6 Koyama, 1998, Nociceptive neurons in the macaque anterior cingulate activate during anticipation of pain., Neuroreport, 9, 2663, 10.1097/00001756-199808030-00044 LaGraize, 2004, Differential effect of anterior cingulate cortex lesion on mechanical hypersensitivity and escapeavoidance behavior in an animal model of neuropathic pain., Exp Neurol, 188, 139, 10.1016/j.expneurol.2004.04.003 Li, 2000, Mechanical hyperalgesia after an L5 spinal nerve lesion in the rat is not dependent on input from injured nerve fibers., Pain, 85, 493, 10.1016/S0304-3959(00)00250-5 Lombard, 1979, Deafferentation hypersensitivity in the rat after dorsal rhizotomy: a possible animal model of chronic pain., Pain, 6, 163, 10.1016/0304-3959(79)90123-4 Moisset, 2007, Brain imaging of neuropathic pain., Neuroimage, 37, S80, 10.1016/j.neuroimage.2007.03.054 Petersen, 2000, Capsaicin evoked pain and allodynia in post-herpetic neuralgia., Pain, 88, 125, 10.1016/S0304-3959(00)00311-0 Petrovic, 1999, A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy., Pain, 83, 459, 10.1016/S0304-3959(99)00150-5 Petrovic, 2002, Placebo and opioid analgesiaimaging a shared neuronal network., Science, 295, 1737, 10.1126/science.1067176 Peyron, 1998, Allodynia after lateral-medullary (Wallenberg) infarct. A PET study., Brain, 121, 345, 10.1093/brain/121.2.345 Pfeiffer, 1986, Psychotomimesis mediated by kappa opiate receptors., Science, 233, 774, 10.1126/science.3016896 Rainville, 1997, Pain affect encoded in human anterior cingulate but not somatosensory cortex., Science, 277, 968, 10.1126/science.277.5328.968 Rice, 2008, Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards., Pain, 139, 243, 10.1016/j.pain.2008.08.017 Ringkamp, 2005, Injured versus uninjured afferents: who is to blame for neuropathic pain?, Anesthesiology, 103, 221, 10.1097/00000542-200508000-00002 Rodin, 1984, Deafferentation in animals as a model for the study of pain: an alternative hypothesis., Brain Res, 319, 213, 10.1016/0165-0173(84)90011-0 Sheen, 1993, Signs of neuropathic pain depend on signals from injured nerve fibers in a rat model., Brain Res, 610, 62, 10.1016/0006-8993(93)91217-G Tracey, 2005, Nociceptive processing in the human brain., Curr Opin Neurobiol, 15, 478, 10.1016/j.conb.2005.06.010 Tracey, 2009, How neuroimaging studies have challenged us to rethink: is chronic pain a disease?, J Pain, 10, 1113, 10.1016/j.jpain.2009.09.001 Treede, 1999, The cortical representation of pain., Pain, 79, 105, 10.1016/S0304-3959(98)00184-5 Tzschentke, 1999, Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization., Eur J Neurosci, 11, 4099, 10.1046/j.1460-9568.1999.00834.x Vierck, 2008, Clinical and pre-clinical pain assessment: are we measuring the same thing?, Pain, 135, 7, 10.1016/j.pain.2007.12.008 Wall, 1984, Cutaneous responsiveness in primary somatosensory (S-I) hindpaw cortex before and after partial hindpaw deafferentation in adult rats., J Neurosci, 4, 1499, 10.1523/JNEUROSCI.04-06-01499.1984 Wall, 1979, Autotomy following peripheral nerve lesions: experimental anaesthesia dolorosa., Pain, 7, 103, 10.1016/0304-3959(79)90002-2 Wall, 1979, The production and prevention of experimental anesthesia dolorosa., Pain, 6, 175, 10.1016/0304-3959(79)90124-6 Witting, 2006, A PET activation study of brush-evoked allodynia in patients with nerve injury pain., Pain, 120, 145, 10.1016/j.pain.2005.10.034 Wu, 2001, Early onset of spontaneous activity in uninjured C-fiber nociceptors after injury to neighboring nerve fibers., J Neurosci, 21, 1, 10.1523/JNEUROSCI.21-08-j0002.2001 Xie, 2005, Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance., J Neurosci, 25, 409, 10.1523/JNEUROSCI.4054-04.2005 Xu, 2008, Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex., J Neurosci, 28, 7445, 10.1523/JNEUROSCI.1812-08.2008 Yaksh, 1976, Chronic catheterization of the spinal subarachnoid space., Physiol Behav, 17, 1031, 10.1016/0031-9384(76)90029-9 Yoon, 1996, Contributions of injured and intact afferents to neuropathic pain in an experimental rat model., Pain, 64, 27, 10.1016/0304-3959(95)00096-8