Early preterm birth: association between in utero exposure to acute inflammation and severe neurodevelopmental disability at 6 years of age

Hamilton, 2007, Annual summary of vital statistics: 2005, Pediatrics, 119, 345, 10.1542/peds.2006-3226 Hack, 2000, Outcomes of children of extremely low birthweight and gestational age in the 1990s, Semin Neonatol, 5, 89, 10.1053/siny.1999.0001 Hack, 2005, Chronic conditions, functional limitations, and special health care needs of school-aged children born with extremely low-birth-weight in the 1990’s, JAMA, 294, 318, 10.1001/jama.294.3.318 Anderson, 2003, Neurobehavioral outcomes of school-age children born extremely low birth weight or very preterm in the 1990’s, JAMA, 289, 3264, 10.1001/jama.289.24.3264 Anderson, 2004, Executive functioning in school-age children who were born very preterm or extremely low birth weight in the 1990’s, Pediatrics, 114, 50, 10.1542/peds.114.1.50 Mikkola, 2005, neurodevelopmental outcome at 5 years of age of a national cohort of extremely low birth weight infants who were born in 1196-1997, Pediatrics, 116, 1391, 10.1542/peds.2005-0171 Goldenberg, 2000, Mechanisms of disease: intrauterine infection and preterm birth, N Engl J Med, 342, 1500, 10.1056/NEJM200005183422007 Romero, 2007, The role of inflammation and infection in preterm birth, Semin Reprod Med, 25, 21, 10.1055/s-2006-956773 Wu, 2003, Chorioamnionitis and cerebral palsy in term and near-term infants, JAMA, 290, 2677, 10.1001/jama.290.20.2677 Nelson, 1985, Antecedents of cerebral palsy, I: univariate analysis of risks, Am J Dis Child, 139, 1031, 10.1001/archpedi.1985.02140120077032 Grether, 1997, Maternal infection and cerebral palsy in infants of normal birthweight, JAMA, 278, 207, 10.1001/jama.1997.03550030047032 Nelson, 1986, Antecedents of cerebral palsy; multivariate analysis of risk, N Engl J Med, 315, 81, 10.1056/NEJM198607103150202 Redline, 1998, Placental lesions associated with neurologic impairment and cerebral palsy in very low-birth-weight infants, Arch Pathol Lab Med, 122, 1091 Barshiri, 2006, Cerebral palsy and the fetal inflammatory response syndrome: a review, J Perinat Med, 34, 5 Yoon, 1997, Amniotic fluid cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy, Am J Obstet Gynecol, 177, 19, 10.1016/S0002-9378(97)70432-0 Yoon, 1996, Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia, Am J Obstet Gynecol, 174, 1433, 10.1016/S0002-9378(96)70585-9 Yoon, 1997, High expression of tumor-necrosis factor-alpha and interleukin-6 in periventricular leukomalacia, Am J Obstet Gynecol, 177, 406, 10.1016/S0002-9378(97)70206-0 Nelson, 1998, Neonatal cytokines and coagulation factors in children with cerebral palsy, Ann Neurol, 44, 665, 10.1002/ana.410440413 Yoon, 2000, Fetal exposure to intra-amniotic cytokines and development of cerebral palsy at age three years, Am J Obstet Gynecol, 182, 675, 10.1067/mob.2000.104207 Goepfert, 2004, Umbilical cord plasma interleukin-6 concentrations in preterm infants and risk of neonatal morbidity, Am J Obstet Gynecol, 191, 1375, 10.1016/j.ajog.2004.06.086 Andrews, 2006, The Alabama preterm birth study: polymorphonuclear and mononuclear cell placental infiltration, other markers of inflammation and outcomes in preterm newborns, Am J Obstet Gynecol, 195, 803, 10.1016/j.ajog.2006.06.083 Goldenberg, 2006, The Alabama preterm birth study: intrauterine infection and placental histologic findings in male and female <32 week preterm births, Am J Obstet Gynecol, 195, 1533, 10.1016/j.ajog.2006.05.023 Goldenberg, 2006, The Alabama preterm birth study: corticosteroids and newborn outcomes in 23-32 week newborns with various markers of placental infection, Am J Obstet Gynecol, 195, 1020, 10.1016/j.ajog.2006.06.033 Goldenberg, 2006, The Alabama preterm birth project: placental histology in recurrent preterm birth, Am J Obstet Gynecol, 195, 792, 10.1016/j.ajog.2006.05.050 Goldenberg, 2006, The Alabama preterm birth study: diffuse decidual leukocytoclastic necrosis of the decidua basalis, a placental lesion associated with preeclampsia, indicated preterm birth, and decreased fetal growth, J Mat Fet Med Goldenberg RL, Andrews WW, Goepfert AR, et al. The Alabama preterm birth study: umbilical cord blood ureaplasma urealyticum and mycoplasma hominis cultures in very preterm newborns. Am J Obstet Gynecol (in press). Waites, 2003, Mycoplasma and ureaplasma, 972 Andrews, 1995, Amniotic fluid interleukin-6: correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery, Am J Obstet Gynecol, 173, 606, 10.1016/0002-9378(95)90290-2 Bendon, 1997, Histologic features of chorioamnion membrane rupture: development of methodology, Pediatr Pathol Lab Med, 17, 27, 10.3109/15513819709168344 Williams, 1997 Wechsler, 2003 Eliot, 1990 Grether, 2003, Intrauterine exposure to infection and risk of cerebral palsy in very preterm infants, Arch Pediatr Adolesc Med, 157, 26, 10.1001/archpedi.157.1.26 Nelson, 2003, Neonatal cytokines and cerebral palsy in very preterm infants, Pediatr Res, 53, 600, 10.1203/01.PDR.0000056802.22454.AB