Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
Tóm tắt
Từ khóa
Tài liệu tham khảo
Backer, 2008, The regulation and function of Class III PI3Ks: novel roles for Vps34, Biochem. J., 410, 1, 10.1042/BJ20071427
Byfield, 2005, hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase, J. Biol. Chem., 280, 33076, 10.1074/jbc.M507201200
Cheong, 2011, Ammonia-induced autophagy is independent of ULK1/ULK2 kinases, Proc. Natl. Acad. Sci. USA, 108, 11121, 10.1073/pnas.1107969108
Di Bartolomeo, 2010, The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy, J. Cell Biol., 191, 155, 10.1083/jcb.201002100
Egan, 2011, Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy, Science, 331, 456, 10.1126/science.1196371
Fimia, 2007, Ambra1 regulates autophagy and development of the nervous system, Nature, 447, 1121, 10.1038/nature05925
Furuya, 2010, Negative regulation of Vps34 by Cdk mediated phosphorylation, Mol. Cell, 38, 500, 10.1016/j.molcel.2010.05.009
Gulati, 2008, Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34, Cell Metab., 7, 456, 10.1016/j.cmet.2008.03.002
Gwinn, 2008, AMPK phosphorylation of raptor mediates a metabolic checkpoint, Mol. Cell, 30, 214, 10.1016/j.molcel.2008.03.003
Hardie, 2007, AMP-activated protein kinase as a drug target, Annu. Rev. Pharmacol. Toxicol., 47, 185, 10.1146/annurev.pharmtox.47.120505.105304
Itakura, 2010, Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins, Autophagy, 6, 764, 10.4161/auto.6.6.12709
Itakura, 2008, Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG, Mol. Biol. Cell, 19, 5360, 10.1091/mbc.E08-01-0080
Johnson, 2006, Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes, J. Cell Sci., 119, 1219, 10.1242/jcs.02833
Kametaka, 1998, Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae, J. Biol. Chem., 273, 22284, 10.1074/jbc.273.35.22284
Kihara, 2001, Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae, J. Cell Biol., 152, 519, 10.1083/jcb.152.3.519
Kim, 2011, AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1, Nat. Cell Biol., 13, 132, 10.1038/ncb2152
Kwon, 2011, CCCP induces autophagy in an AMPK-independent manner, Biochem. Biophys. Res. Commun., 416, 343, 10.1016/j.bbrc.2011.11.038
Liang, 2006, Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG, Nat. Cell Biol., 8, 688, 10.1038/ncb1426
Matsunaga, 2009, Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages, Nat. Cell Biol., 11, 385, 10.1038/ncb1846
Matsunaga, 2010, Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L, J. Cell Biol., 190, 511, 10.1083/jcb.200911141
Nakatogawa, 2009, Dynamics and diversity in autophagy mechanisms: lessons from yeast, Nat. Rev. Mol. Cell Biol., 10, 458, 10.1038/nrm2708
Noble, 2008, Bcl-xL and UVRAG cause a monomer-dimer switch in Beclin1, J. Biol. Chem., 283, 26274, 10.1074/jbc.M804723200
Nobukuni, 2005, Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase, Proc. Natl. Acad. Sci. USA, 102, 14238, 10.1073/pnas.0506925102
Obara, 2011, PtdIns 3-kinase orchestrates autophagosome formation in yeast, J. Lipids, 2011, 498768, 10.1155/2011/498768
Obara, 2006, Assortment of phosphatidylinositol 3-kinase complexes—Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae, Mol. Biol. Cell, 17, 1527, 10.1091/mbc.E05-09-0841
Pattingre, 2005, Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy, Cell, 122, 927, 10.1016/j.cell.2005.07.002
Ropolo, 2007, The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells, J. Biol. Chem., 282, 37124, 10.1074/jbc.M706956200
Sagona, 2010, PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody, Nat. Cell Biol., 12, 362, 10.1038/ncb2036
Sun, 2008, Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase, Proc. Natl. Acad. Sci. USA, 105, 19211, 10.1073/pnas.0810452105
Suzuki, 2007, Hierarchy of Atg proteins in pre-autophagosomal structure organization, Genes Cells, 12, 209, 10.1111/j.1365-2443.2007.01050.x
Takahashi, 2007, Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis, Nat. Cell Biol., 9, 1142, 10.1038/ncb1634
Vergne, 2010, The role of PI3P phosphatases in the regulation of autophagy, FEBS Lett., 584, 1313, 10.1016/j.febslet.2010.02.054
Wei, 2008, JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy, Mol. Cell, 30, 678, 10.1016/j.molcel.2008.06.001
Yang, 2010, Mammalian autophagy: core molecular machinery and signaling regulation, Curr. Opin. Cell Biol., 22, 124, 10.1016/j.ceb.2009.11.014
Zalckvar, 2009, DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy, EMBO Rep., 10, 285, 10.1038/embor.2008.246
Zhong, 2009, Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex, Nat. Cell Biol., 11, 468, 10.1038/ncb1854
Fan, W., Nassiri, A., and Zhong, Q. (2011). Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L). Proc. Natl. Acad. Sci. USA 108, 7769–7774.
Horbinski, C., Stachowiak, M.K., Higgins, D., and Finnegan, S.G. (2001). Polyethyleneimine-mediated transfection of cultured postmitotic neurons from rat sympathetic ganglia and adult human retina. BMC Neurosci. 2, 2.
Kim, J., Yoon, M.Y., Choi, S.L., Kang, I., Kim, S.S., Kim, Y.S., Choi, Y.K., and Ha, J. (2001). Effects of stimulation of AMP-activated protein kinase on insulin-like growth factor 1- and epidermal growth factor-dependent extracellular signal-regulated kinase pathway. J. Biol. Chem. 276, 19102–19110.
Kim, J., Kundu, M., Viollet, B., and Guan, K.L. (2011). AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132–141.