Active polypeptides from Hirudo inhibit endothelial cell inflammation and macrophage foam cell formation by regulating the LOX-1/LXR-α/ABCA1 pathway

Biomedicine & Pharmacotherapy - Tập 115 - Trang 108840 - 2019
Jing Lu1,2, Xuenan Chen1,2, Xiaohao Xu1,2, Jianzeng Liu2,3, Zepeng Zhang1,2, Mingxing Wang1,2, Xiangzhu Li4, Hong Chen4, Daqing Zhao2,3, Jian Wang5, Dexi Zhao5, Deyu Cong6, Xiangyan Li2,3, Liwei Sun1,7
1Research Center of Traditional Chinese Medicine, the Affiliated Hospital to Changchun University of Chinese Medicine, Jilin, China
2Jilin Provincial Key Laboratory of BioMacromolecules of Chinese Medicine, Changchun University of Chinese Medicine, Jilin, China
3Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, China
4Tonghua Dongbao Pharmaceutical Co. Ltd, Jilin, China
5Department of Encephalopathy, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, China
6Department of Tuina, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, China
7Jilin Technology Innovation Center for Chinese Medicine Biotechnology, Beihua University, Jilin, China

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