Electron transport chain dysfunction in neonatal pressure-overload hypertrophy precedes cardiomyocyte apoptosis independent of oxidative stress

The Journal of Thoracic and Cardiovascular Surgery - Tập 139 - Trang 1609-1617 - 2010
Eric R. Griffiths1, Ingeborg Friehs1, Elisabeth Scherr1, Dimitrios Poutias1, Francis X. McGowan1, Pedro J. del Nido1
1Departments of Cardiac Surgery and Anesthesiology, Perioperative and Pain, Children's Hospital Boston, Harvard Medical School, Boston, Mass

Tài liệu tham khảo

Frey, 2003, Cardiac hypertrophy: the good, the bad, and the ugly, Ann Rev Physiol, 65, 45, 10.1146/annurev.physiol.65.092101.142243 Choi, 2009, Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium, J Thorac Cardiovasc Surg, 137, 1356, 10.1016/j.jtcvs.2008.12.020 Friehs, 2006, Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart, Circulation, 114, I290 Stanley, 2005, Myocardial substrate metabolism in the normal and failing heart, Physiol Rev, 85, 1093, 10.1152/physrev.00006.2004 Beer, 2002, Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy, J Am Coll Cardiol, 40, 1267, 10.1016/S0735-1097(02)02160-5 Watanabe, 2006, Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells, Am J Pathol, 168, 1737, 10.2353/ajpath.2006.050648 Tsutsui, 2006, Mitochondrial oxidative stress, DNA damage, and heart failure, Antioxid Redox Signaling, 8, 1737, 10.1089/ars.2006.8.1737 Lee, 1997, Role of mitochondria in human aging, J Biomed Sci, 4, 319, 10.1007/BF02258357 Sugden, 2006, Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytes, Antioxid Redox Signaling, 8, 2111, 10.1089/ars.2006.8.2111 Tu, 2002, Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase, J Pharmacol Expl Ther, 300, 1101, 10.1124/jpet.300.3.1101 Kumar, 2003, Apoptosis and oxidants in the heart, J Lab Clin Med, 142, 288, 10.1016/S0022-2143(03)00148-3 Chen, 2008, Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria, Am J Physiol Cell Physiol, 294, C460, 10.1152/ajpcell.00211.2007 Friehs, 2005, Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury, Biochem Biophys Res Commun, 331, 15, 10.1016/j.bbrc.2005.03.120 Moran, 2003, Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardium, Herz, 28, 52, 10.1007/s00059-003-2392-0 Friehs, 2004, Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury, Ann Thorac Surg, 77, 2004, 10.1016/j.athoracsur.2003.11.003 Rousou, 2004, Opening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration, Am J Physiol, 287, H1967 Birch-Machin, 1994, An evaluation of the measurement of the activities of complexes I-IV in the respiratory chain of human skeletal muscle mitochondria, Biochem Med Metab Biol, 51, 35, 10.1006/bmmb.1994.1004 2002 Bache, 1999, Myocardial oxygenation at high workstates in hearts with left ventricular hypertrophy, Cardiovasc Res, 42, 616, 10.1016/S0008-6363(98)00332-0 Ingwall, 2009, Energy metabolism in heart failure and remodelling, Cardiovasc Res, 81, 412, 10.1093/cvr/cvn301 Porcelli, 2009, Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels, J Biol Chem, 284, 2045, 10.1074/jbc.M807321200 Hirst, 2003, The nuclear encoded subunits of complex I from bovine heart mitochondria, Biochim Biophys Acta, 1604, 135, 10.1016/S0005-2728(03)00059-8 Rustin, 2002, Inborn errors of complex II—unusual human mitochondrial diseases, Biochim Biophys Acta, 1553, 117, 10.1016/S0005-2728(01)00228-6 Fontanesi, 2008, Cytochrome c oxidase biogenesis: new levels of regulation, IUBMB Life, 60, 557, 10.1002/iub.86 Fukuda, 2007, HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells, Cell, 129, 111, 10.1016/j.cell.2007.01.047 Balaban, 2009, Domestication of the cardiac mitochondrion for energy conversion, J Mol Cell Cardiol, 46, 832, 10.1016/j.yjmcc.2009.02.018 Kim, 2006, Substrate and functional diversity of lysine acetylation revealed by a proteomics survey, Mol Cell, 23, 607, 10.1016/j.molcel.2006.06.026 Li, 2002, Activation of NADPH oxidase during progression of cardiac hypertrophy to failure, Hypertension, 40, 477, 10.1161/01.HYP.0000032031.30374.32 Loor, 2008, Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion, Cell Death Differ, 15, 686, 10.1038/cdd.2008.13 Kido, 2005, Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse, J Am Coll Cardiol, 46, 2116, 10.1016/j.jacc.2005.08.045 Friehs, 2005, Deferoxamine mediated activation of hypoxia inducible factor-1α (HIF-1α) upregulates target genes for protection of hypertrophied myocardium, Circulation, 112