Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia-induced transactivation of endothelin-1
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Boulanger, 1999, Secondary endothelial dysfunction: hypertension and heart failure, J. Mol. Cell Cardiol., 31, 39, 10.1006/jmcc.1998.0842
Schermuly, 2011, Mechanisms of disease: pulmonary arterial hypertension, Nat. Rev. Cardiol., 8, 443, 10.1038/nrcardio.2011.87
Belin de Chantemele, 2012, Influence of obesity and metabolic dysfunction on the endothelial control in the coronary circulation, J. Mol. Cell Cardiol., 52, 840, 10.1016/j.yjmcc.2011.08.018
Fonseca, 2011, Endothelin in pulmonary fibrosis, Am. J. Respir. Cell Mol. Biol., 44, 1, 10.1165/rcmb.2009-0388TR
Golden, 1995, Effects of vasoactive and inflammatory mediators on endothelin-1 expression in pulmonary endothelial cells, Am. J. Respir. Cell Mol. Biol., 12, 503, 10.1165/ajrcmb.12.5.7742014
Dschietzig, 2001, Dexamethasone inhibits stimulation of pulmonary endothelins by proinflammatory cytokines: possible involvement of a nuclear factor kappa B dependent mechanism, Intensive Care Med., 27, 751, 10.1007/s001340100882
Cheng, 2001, Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells, J. Mol. Cell Cardiol., 33, 1805, 10.1006/jmcc.2001.1444
Juan, 2004, 17beta-estradiol inhibits cyclic strain-induced endothelin-1 gene expression within vascular endothelial cells, Am. J Physiol. Heart Circ. Physiol., 287, H1254, 10.1152/ajpheart.00723.2003
Wang, 2002, Potentiation of serum response factor activity by a family of myocardin-related transcription factors, Proc. Natl Acad. Sci. USA, 99, 14855, 10.1073/pnas.222561499
Cen, 2004, Myocardin/MKL family of SRF coactivators: key regulators of immediate early and muscle specific gene expression, J. Cell. Biochem., 93, 74, 10.1002/jcb.20199
Small, 2010, Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction, Circ. Res., 107, 294, 10.1161/CIRCRESAHA.110.223172
Kuwahara, 2010, Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression, Mol. Cell. Biol., 30, 4134, 10.1128/MCB.00154-10
Fang, 2011, Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury, Circ. Res., 108, 797, 10.1161/CIRCRESAHA.111.240655
Hanna, 2009, Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase, J. Biol. Chem., 284, 23125, 10.1074/jbc.M109.019059
Lockman, 2007, The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression, Circ. Res., 101, e115, 10.1161/CIRCRESAHA.107.164178
Zhou, 2009, The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression, Arterioscler Thromb Vasc. Biol., 29, 921, 10.1161/ATVBAHA.109.187229
Zhang, 2007, A novel role of Brg1 in the regulation of SRF/MRTFA-dependent smooth muscle-specific gene expression, J. Biol. Chem., 282, 25708, 10.1074/jbc.M701925200
Goerre, 1995, Endothelin-1 in pulmonary hypertension associated with high-altitude exposure, Circulation, 91, 359, 10.1161/01.CIR.91.2.359
Yamashita, 2001, Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP, J. Biol. Chem., 276, 12645, 10.1074/jbc.M011344200
Sun, 2006, Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function, Mol. Cell. Biol., 26, 5809, 10.1128/MCB.00024-06
Tian, 2012, Brahma related gene 1 (Brg1) bridges epigenetic regulation of pro-inflammatory cytokine production to steatohepatitis, Hepatology
Fang, 2009, RFXB and its splice variant RFXBSV mediate the antagonism between IFNgamma and TGFbeta on COL1A2 transcription in vascular smooth muscle cells, Nucleic Acids Res., 37, 4393, 10.1093/nar/gkp398
Wort, 2009, Synergistic induction of endothelin-1 by tumor necrosis factor alpha and interferon gamma is due to enhanced NF-kappaB binding and histone acetylation at specific kappaB sites, J. Biol. Chem., 284, 24297, 10.1074/jbc.M109.032524
Chen, 2010, Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells, Am.J. Physiol. Endocrinol. Metab., 298, E127, 10.1152/ajpendo.00432.2009
Xia, 2009, Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis, Proc. Natl Acad. Sci. USA, 106, 4260, 10.1073/pnas.0810067106
Hang, 2010, Chromatin regulation by Brg1 underlies heart muscle development and disease, Nature, 466, 62, 10.1038/nature09130
Naito, 2009, BRG1 increases transcription of proinflammatory genes in renal ischemia, J. Am. Soc. Nephrol., 20, 1787, 10.1681/ASN.2009010118
Zager, 2009, Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/profibrotic genes, Am. J. Physiol. Renal Physiol., 296, F1032, 10.1152/ajprenal.00061.2009
Morin, 2001, Serum response factor-GATA ternary complex required for nuclear signaling by a G-protein-coupled receptor, Mol. Cell. Biol., 21, 1036, 10.1128/MCB.21.4.1036-1044.2001
Davis, 2003, Functional significance of protein kinase A activation by endothelin-1 and ATP: negative regulation of SRF-dependent gene expression by PKA, Cell. Signal., 15, 597, 10.1016/S0898-6568(02)00148-1
Marshall, 2010, ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes, PLoS One, 5, e10027, 10.1371/journal.pone.0010027
Olson, 2010, Linking actin dynamics and gene transcription to drive cellular motile functions, Nat. Rev. Mol. Cell. Biol., 11, 353, 10.1038/nrm2890
Wojciak-Stothard, 2006, Rac1 and RhoA as regulators of endothelial phenotype and barrier function in hypoxia-induced neonatal pulmonary hypertension, Am. J. Physiol. Lung Cell Mol. Physiol., 290, L1173, 10.1152/ajplung.00309.2005
Wojciak-Stothard, 2012, Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia, Circ. Res., 110, 1423, 10.1161/CIRCRESAHA.112.264473
Wojciak-Stothard, 2005, Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells, Am. J. Physiol. Lung Cell Mol. Physiol., 288, L749, 10.1152/ajplung.00361.2004
Cen, 2003, Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes, Mol. Cell. Biol., 23, 6597, 10.1128/MCB.23.18.6597-6608.2003
Lee, 2010, Activation and repression of cellular immediate early genes by serum response factor cofactors, J. Biol. Chem., 285, 22036, 10.1074/jbc.M110.108878
Solway, 1995, Structure and expression of a smooth muscle cell-specific gene, SM22 alpha, J. Biol. Chem., 270, 13460, 10.1074/jbc.270.22.13460
de La Serna, 2000, Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene, Mol. Cell. Biol., 20, 2839, 10.1128/MCB.20.8.2839-2851.2000
Du, 2004, Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells, J. Biol. Chem., 279, 17578, 10.1074/jbc.M400961200
Glenn, 2009, Atrial natriuretic peptide suppresses endothelin gene expression and proliferation in cardiac fibroblasts through a GATA4-dependent mechanism, Cardiovasc. Res., 84, 209, 10.1093/cvr/cvp208