Modulation of peroxisome proliferator–activated receptor γ stability and transcriptional activity in adipocytes by resveratrol

Metabolism - Tập 57 - Trang S32-S38 - 2008
Z. Elizabeth Floyd1, Zhong Q. Wang2, Gail Kilroy1, William T. Cefalu2
1Ubiquitin Biology Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA
2Diabetes and Nutrition Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA

Tài liệu tham khảo

Lagouge, 2006, Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1[alpha], Cell, 127, 1109, 10.1016/j.cell.2006.11.013 Baur, 2006, Resveratrol improves health and survival of mice on a high-calorie diet, Nature, 444, 280, 10.1038/nature05354 Picard, 2004, Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma, Nature, 429, 771, 10.1038/nature02583 Howitz, 2003, Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan, Nature, 425, 191, 10.1038/nature01960 Kliewer, 1997, Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator–activated receptors alpha and gamma, Proc Natl Acad Sci U S A, 94, 4318, 10.1073/pnas.94.9.4318 Medina-Gomez, 2005, The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator–activated receptor–gamma2 isoform, Diabetes, 54, 1706, 10.2337/diabetes.54.6.1706 Kubota, 1999, PPAR gamma mediates high-fat diet–induced adipocyte hypertrophy and insulin resistance, Mol Cell, 4, 597, 10.1016/S1097-2765(00)80210-5 Miles, 2003, Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding, Am J Physiol Endocrinol Metab, 284, E618, 10.1152/ajpendo.00312.2002 Miles, 2000, Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency, J Clin Invest, 105, 287, 10.1172/JCI8538 Rieusset, 2004, Altered growth in male peroxisome proliferator–activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action, Mol Endocrinol, 18, 2363, 10.1210/me.2003-0325 Stewart, 2004, STAT 5 activators can replace the requirement of FBS in the adipogenesis of 3T3-L1 cells, Biochem Biophys Res Commun, 324, 355, 10.1016/j.bbrc.2004.09.053 Floyd, 2002, Interferon-gamma–mediated activation and ubiquitin-proteasome–dependent degradation of PPARgamma in adipocytes, J Biol Chem, 277, 4062, 10.1074/jbc.M108473200 Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0 Waite, 2001, Interferon-gamma–induced regulation of peroxisome proliferator–activated receptor gamma and STATs in adipocytes, J Biol Chem, 276, 7062, 10.1074/jbc.M007894200 Gomez-Lechon, 1996, A microassay for measuring glycogen in 96-well cultured cells, Anal Biochem, 236, 296, 10.1006/abio.1996.0170 Hauser, 2000, Degradation of the peroxisome proliferator–activated receptor gamma is linked to ligand-dependent activation, J Biol Chem, 275, 18527, 10.1074/jbc.M001297200 Ge, 2007, Resveratrol inhibits macrophage expression of EMMPRIN by activating PPARgamma, Vasc Pharmacol, 46, 114, 10.1016/j.vph.2006.08.412 Inoue, 2003, Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator–activated receptor alpha in mice, Neurosci Lett, 352, 203, 10.1016/j.neulet.2003.09.001 Ulrich, 2006, Peroxisome proliferator–activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism, Cancer Res, 66, 7348, 10.1158/0008-5472.CAN-05-2777 Yan, 2006, Pim-1 kinase inhibits the activation of reporter gene expression in Elk-1 and c-Fos reporting systems but not the endogenous gene expression: an artifact of the reporter gene assay by transient co-transfection, Braz J Med Biol Res, 39, 169, 10.1590/S0100-879X2006000200002 Chattopadhyay, 1998, A nuclear matrix attachment region upstream of the T cell receptor beta gene enhancer binds Cux/CDP and SATB1 and modulates enhancer-dependent reporter gene expression but not endogenous gene expression, J Biol Chem, 273, 29838, 10.1074/jbc.273.45.29838 Schoonjans, 1996, The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation, Biochim Biophys Acta, 1302, 93, 10.1016/0005-2760(96)00066-5 Hua, 1991, Cloning and characterization of the promoter of the murine lipoprotein lipase–encoding gene: structural and functional analysis, Gene, 107, 247, 10.1016/0378-1119(91)90325-6 Tontonoz, 1994, mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer, Genes Dev, 8, 1224, 10.1101/gad.8.10.1224 Devine, 1999, Adipose expression of the phosphoenolpyruvate carboxykinase promoter requires peroxisome proliferator–activated receptor gamma and 9-cis-retinoic acid receptor binding to an adipocyte-specific enhancer in vivo, J Biol Chem, 274, 13604, 10.1074/jbc.274.19.13604 Tontonoz, 1995, PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene, Mol Cell Biol, 15, 351, 10.1128/MCB.15.1.351 Tordjman, 2003, Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells, J Biol Chem, 278, 18785, 10.1074/jbc.M206999200 Brady, 1998, The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells, J Biol Chem, 273, 14063, 10.1074/jbc.273.23.14063 Jensen, 2000, Specific desensitization of glycogen synthase activation by insulin in 3T3-L1 adipocytes. Connection between enzymatic activation and subcellular localization, J Biol Chem, 275, 40148, 10.1074/jbc.M004902200 Lehmann, 1995, An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator–activated receptor gamma (PPARgamma), J Biol Chem, 270, 12953, 10.1074/jbc.270.22.12953 Gray, 2006, Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator–activated receptor gamma function (P465L PPARgamma) in mice, Diabetes, 55, 2669, 10.2337/db06-0389 Larsen, 2003, PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?, Int J Obes Relat Metab Disord, 27, 147, 10.1038/sj.ijo.802223 Floyd, 2004, Control of peroxisome proliferator–activated receptor gamma2 stability and activity by SUMOylation, Obes Res, 12, 921, 10.1038/oby.2004.112 Koubova, 2003, How does calorie restriction work?, Genes Dev, 17, 313, 10.1101/gad.1052903 Bluher, 2003, Extended longevity in mice lacking the insulin receptor in adipose tissue, Science, 299, 572, 10.1126/science.1078223 Barzilai, 2001, The role of fat depletion in the biological benefits of caloric restriction, J Nutr, 131, 903S, 10.1093/jn/131.3.903S Liao, 2007, Suppression of PPARγ attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes, Am J Physiol Endocrinol Metab, 293, E219, 10.1152/ajpendo.00695.2006