Advancing age is associated with gene expression changes resembling mTOR inhibition: Evidence from two human populations

Mechanisms of Ageing and Development - Tập 133 - Trang 556-562 - 2012
Lorna W. Harries1, Alexander D. Fellows1, Luke C. Pilling2, Dena Hernandez3, Andrew Singleton3, Stefania Bandinelli4, Jack Guralnik5, Jonathan Powell2, Luigi Ferrucci6, David Melzer2
1Institute of Biomedical and Clinical Sciences, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX2 5DW, UK
2Epidemiology and Public Health, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX2 5DW, UK
3Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 USA
4Geriatric Unit, Azienda Sanitaria di Firenze, Florence, Italy
5University of Maryland School of Medicine, Baltimore, MD, USA
6National Institute on Aging, Baltimore, MD, USA

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