Contribution of cytochrome P450 1B1 to hypertension and associated pathophysiology: A novel target for antihypertensive agents

Esler, 2000, The sympathetic system and hypertension, Am J Hypertens, 13, S99, 10.1016/S0895-7061(00)00225-9 Carey, 2011, Overview of endocrine systems in primary hypertension, Endocrinol Metab Clin North Am, 40, 265, 10.1016/j.ecl.2011.01.003 Rao, 1994, Angiotensin II stimulates phosphorylation of high-molecular-mass cytosolic phospholipase A2 in vascular smooth-muscle cells, Biochem J, 299, 197, 10.1042/bj2990197 Muthalif, 1996, Calcium/calmodulin-dependent protein kinase IIα mediates activation of mitogen-activated protein kinase and cytosolic phospholipase A2 in norepinephrine-induced arachidonic acid release in rabbit aortic smooth muscle cells, J Biol Chem, 271, 30149, 10.1074/jbc.271.47.30149 Muthalif, 1998, Signal transduction mechanisms involved in angiotensin-(1–7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cells, J Pharmacol Exp Ther, 284, 388 Nasjletti, 1982, Interrelations between prostaglandins and vasoconstrictor hormones: contribution to blood pressure regulation, Fed Proc, 41, 2394 McGiff, 1981, Prostaglandins, prostacyclin, and thromboxanes, Annu Rev Pharmacol Toxicol, 21, 479, 10.1146/annurev.pa.21.040181.002403 Nasjletti, 1998, Corcoran Memorial Lecture: the role of eicosanoids in angiotensin-dependent hypertension, Hypertension, 31, 194, 10.1161/01.HYP.31.1.194 McGiff, 2001, 20-Hydroxyeicosatetraenoic acid and epoxyeicosatrienoic acids and blood pressure, Curr Opin Nephrol Hypertens, 10, 231, 10.1097/00041552-200103000-00012 Nozawa, 1990, Inhibition of lipoxygenase pathway reduces blood pressure in renovascular hypertensive rats, Am J Physiol Heart Circ Physiol, 259, H1774, 10.1152/ajpheart.1990.259.6.H1774 Smith, 1980, Reactive oxygen production associated with arachidonic acid metabolism by peritoneal macrophages, Biochem Biophys Res Commun, 97, 973, 10.1016/0006-291X(80)91472-2 Lee, 2008, Redox signaling, vascular function, and hypertension, Antioxid Redox Signal, 10, 1045, 10.1089/ars.2007.1986 Hong, 2001, Supplemention with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats, Hypertension, 38, 1044, 10.1161/hy1101.095331 Rajagopalan, 1996, Angiotensin II–mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone, J Clin Invest, 97, 1916, 10.1172/JCI118623 Landmesser, 2003, Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension, J Clin Invest, 111, 1201, 10.1172/JCI200314172 Roman, 2002, P-450 metabolites of arachidonic acid in the control of cardiovascular function, Physiol Rev, 82, 131, 10.1152/physrev.00021.2001 Shimada, 1996, Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1, Cancer Res, 56, 2979 Shimada, 2004, Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1, Cancer Sci, 95, 1, 10.1111/j.1349-7006.2004.tb03162.x Hayes, 1996, 17β-Estradiol hydroxylation catalyzed by human cytochrome P450 1B1, Proc Natl Acad Sci USA, 93, 9776, 10.1073/pnas.93.18.9776 Choudhary, 2004, Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1B1, Drug Metab Dispos, 32, 840, 10.1124/dmd.32.8.840 Sutter, 1994, Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2, J Biol Chem, 269, 13092, 10.1016/S0021-9258(17)36803-5 Tang, 1996, Isolation and characterization of the human CYP1B1 gene, J Biol Chem, 271, 28324, 10.1074/jbc.271.45.28324 Korashy, 2006, The role of aryl hydrocarbon receptor in the pathogenesis of cardiovascular diseases, Drug Metab Rev, 38, 411, 10.1080/03602530600632063 McFadyen, 2004, Cytochrome P450 enzymes: novel options for cancer therapeutics, Mol Cancer Ther, 3, 363, 10.1158/1535-7163.363.3.3 Ryu, 1999, Constitutive expression and induction of CYP1B1 mRNA in the mouse, J Biochem Mol Toxicol, 13, 249, 10.1002/(SICI)1099-0461(1999)13:5<249::AID-JBT4>3.0.CO;2-L Zhao, 1998, Constitutive and inducible expression of cytochrome P450IA1 and P450IB1 in human vascular endothelial and smooth muscle cells, In Vitro Cell Dev Biol Anim, 34, 671, 10.1007/s11626-998-0060-7 Kerzee, 2001, Constitutive and inducible expression of Cyp1a1 and Cyp1b1 in vascular smooth muscle cells. Role of the Ahr bHLH/PAS transcription factor, Circ Res, 89, 573, 10.1161/hh1901.097083 Conway, 2009, Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress, Cardiovasc Res, 81, 669, 10.1093/cvr/cvn360 Tang, 2009, CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression, Blood, 113, 744, 10.1182/blood-2008-03-145219 Yaghini, 2010, Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generation, Hypertension, 55, 1461, 10.1161/HYPERTENSIONAHA.110.150029 Wilcox, 2008, Chemistry and antihypertensive effects of tempol and other nitroxides, Pharmacol Rev, 60, 418, 10.1124/pr.108.000240 Jennings, 2010, Cytochrome P450 1B1 contributes to angiotensin II–induced hypertension and associated pathophysiology, Hypertension, 56, 667, 10.1161/HYPERTENSIONAHA.110.154518 Crofton, 1979, The importance of vasopressin in the development and maintenance of DOC-salt hypertension in the rat, Hypertension, 1, 31, 10.1161/01.HYP.1.1.31 de Champlain, 1987, Abnormal regulation of the sympathoadrenal system in deoxycorticosterone acetate-salt hypertensive rats, Can J Physiol Pharmacol, 65, 1605, 10.1139/y87-252 Drolet, 1989, Enhanced sympathoadrenal reactivity to haemorrhagic stress in DOCA-salt hypertensive rats, J Hypertens, 7, 237, 10.1097/00004872-198903000-00011 Schiffrin, 1995, Antihypertensive effect of an endothelin receptor antagonist in DOCA-salt spontaneously hypertensive rats, Br J Pharmacol, 115, 1377, 10.1111/j.1476-5381.1995.tb16626.x Bonventre, 1988, Calcium dependency of prostaglandin E2 production in rat glomerular mesangial cells. Evidence that protein kinase C modulates the Ca2+ dependent activation of phospholipase A2, J Clin Invest, 82, 168, 10.1172/JCI113566 Trevisi, 2000, Endothelin-1 induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathway, Biochem Pharmacol, 264, 425 Sahan-Firat, 2010, 2,3(,4,5(-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B1, Am J Physiol Heart Circ Physiol, 299, H1891, 10.1152/ajpheart.00655.2010 Sarr, 2006, Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase, Cardiovasc Res, 71, 794, 10.1016/j.cardiores.2006.05.022 Mori, 2004, Role of pressure in angiotensin II-induced renal injury. Chronic servo-control of renal perfusion pressure in rats, Hypertension, 43, 752, 10.1161/01.HYP.0000120971.49659.6a Jin, 2009, Effects of renal perfusion pressure on renal medullary hydrogen peroxide and nitric oxide production, Hypertension, 53, 1048, 10.1161/HYPERTENSIONAHA.109.128827 Agarwal, 2003, Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade, Am J Physiol Renal Physiol, 284, F863, 10.1152/ajprenal.00385.2002 Reckelhoff, 2003, Role of oxidative stress in angiotensin-induced hypertension, Am J Physiol Regul Integr Comp Physiol, 284, R893, 10.1152/ajpregu.00491.2002 Welch, 2005, Angiotensin-induced defects in renal oxygenation: role of oxidative stress, Am J Physiol Heart Circ Physiol, 288, H22, 10.1152/ajpheart.00626.2004 Jennings, 2011, Involvement of cytochrome P450 1B1 to renal dysfunction, injury and inflammation associated with angiotensin II-induced hypertension in rats, Am J Physiol Renal Physiol Jennings, 2011, Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice, Hypertension Polichnowski, 2011, Renal injury in angiotensin II+l-NAME-induced hypertensive rats is independent of elevated blood pressure, Am J Physiol Renal Physiol, 300, F1008, 10.1152/ajprenal.00354.2010 Medhora, 2008, 20-HETE increases superoxide production and activates NADPH oxidase in pulmonary artery endothelial cells, Am J Physiol Lung Cell Mol Physiol, 294, L902, 10.1152/ajplung.00278.2007 Wen, 2008, Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages, Am J Physiol Heart Circ Physiol, H1933, 10.1152/ajpheart.00260.2007 Eid, 2009, Mechanisms of podocyte injury in diabetes. Role of cytochrome P450 and NADPH oxidases, Diabetes, 58, 1201, 10.2337/db08-1536 Cat, 2011, Cell signaling of angiotensin II on vascular tone: novel mechanisms, Curr Hypertens Rep, 13, 122, 10.1007/s11906-011-0187-x Higuchi, 2007, Angiotensin II signal transduction through the AT1 receptor: novel insights into mechanisms and pathophysiology, Clin Sci, 112, 417, 10.1042/CS20060342 Callera, 2005, Responses to c-Src–dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats, Hypertension, 46, 1032, 10.1161/01.HYP.0000176588.51027.35 Mehta, 2007, Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system, Am J Physiol Cell Physiol, 292, C82, 10.1152/ajpcell.00287.2006