Diffusion-weighted magnetic resonance imaging for the detection of lipid-rich necrotic core in carotid atheroma in vivo

Neuroradiology - Tập 52 Số 10 - Trang 929-936 - 2010
Victoria Young1, Andrew J. Patterson1, Umar Sadat1, David J. Bowden1, Martin J. Graves1, Tjun Yip Tang1, Andrew N. Priest1, Jeremy N. Skepper2, Peter J. Kirkpatrick3, Jonathan H. Gillard1
1University Department of Radiology, Addenbrooke's Hospital, Box 218, Hills Road, Cambridge, CB2 0QQ, UK
2Multi-Imaging Centre, University of Cambridge, Cambridge, UK
3Department of Neurosurgery, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK

Tóm tắt

Từ khóa


Tài liệu tham khảo

Yuan C et al (2001) Carotid atherosclerotic plaque: noninvasive MR characterization and identification of vulnerable lesions. Radiology 221(2):285–299

World Health Report: facts and figures. (2003) World Health Organisation: Geneva

Aronow WS et al (1999) Association of extracranial carotid arterial disease and chronic atrial fibrillation with the incidence of new thromboembolic stroke in 1,846 older persons. Am J Cardiol 83(9):1403–1404, A8

1995. Risk of stroke in the distribution of an asymptomatic carotid artery. The European Carotid Surgery Trialists Collaborative Group. Lancet, 345(8944):209–212.

1991. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 325(7):445–453

Libby P (2002) Inflammation in atherosclerosis. Nature 420(6917):868–874

Davies MJ (1996) Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995. Circulation 94(8):2013–2020

Trivedi RA et al (2004) MRI-derived measurements of fibrous-cap and lipid-core thickness: the potential for identifying vulnerable carotid plaques in vivo. Neuroradiology 46(9):738–743

Yuan C et al (1998) Measurement of atherosclerotic carotid plaque size in vivo using high resolution magnetic resonance imaging. Circulation 98(24):2666–2671

Stary HC et al (1995) A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 92(5):1355–1374

Li ZY et al (2008) Assessment of carotid plaque vulnerability using structural and geometrical determinants. Circ J 72(7):1092–1099

Corti R et al (2001) Effects of lipid-lowering by simvastatin on human atherosclerotic lesions: a longitudinal study by high-resolution, noninvasive magnetic resonance imaging. Circulation 104(3):249–252

Wasserman BA et al (2002) Carotid artery atherosclerosis: in vivo morphologic characterization with gadolinium-enhanced double-oblique MR imaging initial results. Radiology 223(2):566–573

Yuan C et al (2008) MRI of carotid atherosclerosis. J Nucl Cardiol 15(2):266–275

Kerwin WS et al (2006) Inflammation in carotid atherosclerotic plaque: a dynamic contrast-enhanced MR imaging study. Radiology 241(2):459–468

Radiologists, T.R.C.o. (2007) Gadolinium-based contrast media and nephrogenic systemic fibrosis. The Royal College of Radiologists London

Bongartz G, Mayr M, Bilecen D (2008) Magnetic resonance angiography (MRA) in renally impaired patients: when and how. Eur J Radiol 66(2):213–219

Schlaudecker JD, Bernheisel CR (2009) Gadolinium-associated nephrogenic systemic fibrosis. Am Fam Physician 80(7):711–714

van der Molen AJ (2008) Nephrogenic systemic fibrosis and the role of gadolinium contrast media. J Med Imaging Radiat Oncol 52(4):339–350

Clarke SE et al (2003) Quantitative assessment of carotid plaque composition using multicontrast MRI and registered histology. Magn Reson Med 50(6):1199–1208

Qiao Y et al (2007) Identification of atherosclerotic lipid deposits by diffusion-weighted imaging. Arterioscler Thromb Vasc Biol 27(6):1440–1446

Yuan C et al (2006) MRI of atherosclerosis in clinical trials. NMR Biomed 19(6):636–654

Greenspan P, Mayer EP, Fowler SD (1985) Nile red: a selective fluorescent stain for intracellular lipid droplets. J Cell Biol 100(3):965–973

Cai JM et al (2002) Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging. Circulation 106(11):1368–1373

Zhao XQ et al (2001) Effects of prolonged intensive lipid-lowering therapy on the characteristics of carotid atherosclerotic plaques in vivo by MRI: a case–control study. Arterioscler Thromb Vasc Biol 21(10):1623–1629

Zhao XQ et al (2007) Testing the hypothesis of atherosclerotic plaque lipid depletion during lipid therapy by magnetic resonance imaging: study design of Carotid Plaque Composition Study. Am Heart J 154(2):239–246