Dammarane-type saponins from steamed leaves of Panax Notoginseng

Natural Products and Bioprospecting - Tập 1 - Trang 124-128 - 2011
Qing Liu1, Jun-Jiang Lv1,2, Min Xu1, Dong Wang1, Hong-Tao Zhu1, Chong-Ren Yang1,3, Ying-Jun Zhang1
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
2Graduate University of Chinese Academy of Sciences, Beijing, China
3Weihe Biotech Research and Development Center, Yuxi, China

Tóm tắt

Four new dammarane-type triterpenoid saponins, namely notoginsenosides SFt1-SFt4 (1–4) were isolated from the steamed leaves of Panax notoginseng (Burk.) F. H. Chen (Araliaceae), together with 17 known saponins. Their structures were established on the basis of detailed spectroscopic analyses and acidic hydrolysis. The known ginsenosides Rk2 and Rh3 were obtained from P. notoginseng for the first time. All of these new saponins showed no in vitro cytotoxicity against five human cancer cell lines (HL-60, SMMC-7712, A-549, MCF-7, and SW480).

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