The contribution of university research to the growth of academic start-ups: an empirical analysis
Tóm tắt
The aim of this paper is to analyze empirically under which circumstances the universities located in a geographical area contribute to the growth of a special category of local new technology-based firms (NTBFs), those established by academic personnel (academic start-ups, ASUs). We examine the effects of a series of characteristics of local universities on the growth rates of ASUs and we compare them with the effects of the same university characteristics on the growth of other (i.e., non-academic) NTBFs. In the empirical part of the paper, we estimate an augmented Gibrat law panel data model using a longitudinal dataset composed of 487 Italian NTBFs observed from 1994 to 2003. Out of these NTBFs 48 are ASUs. The results of the econometric estimates suggest that universities do influence the growth rates of local ASUs, while the effects on the growth rates of other NTBFs are negligible. In particular, the scientific quality of the research performed by universities has a positive effect on the growth rates of ASUs; conversely the commercial orientation of research has a negative effect. These results indicate that universities producing high-quality scientific research have a beneficial impact on the growth of local high-tech start-ups, but only if these firms are able to detect, absorb, and use this knowledge. In this perspective, a greater commercial orientation of university research leading to a reduction of the knowledge available for absorption by these companies, can be detrimental.
Tài liệu tham khảo
Acs, Z. J., Audretsch, D. B., & Feldman, M. P. (1992). Real effects of academic research. The American Economic Review, 82(1), 363–367.
Acs, Z. J., Audretsch, D. B., & Feldman, M. P. (1994). R&D spillovers and recipient firm size. The Review of Economics and Statistics, 76(2), 336–340. doi:10.2307/2109888.
Agrawal, A. (2001). University-to-industry knowledge transfer: Literature review and unanswered questions. International Journal of Management Reviews, 3(4), 285–302. doi:10.1111/1468-2370.00069.
Aldrich, H. E., Kallenberg, A., Marsden, P., & Cassell, J. (1989). In pursuit of evidence: Sampling procedures for locating new businesses. Journal of Business Venturing, 4(6), 367–386. doi:10.1016/0883-9026(89)90008-6.
Anselin, L., Varga, A., & Acs, Z. J. (1997). Local geographic spillovers between University research and high technology innovations. Journal of Urban Economics, 42(3), 422–448. doi:10.1006/juec.1997.2032.
Arellano, M., & Bond, S. (1991). Some tests of specification for panel data: Monte Carlo evidence and an application to employment equations. The Review of Economic Studies, 58(2), 277–297. doi:10.2307/2297968.
Argyres, N. S., & Liebeskind, J. P. (1998). Privatizing the intellectual commons: Universities and the commercialization of biotechnology. Journal of Economic Behavior & Organization, 35(4), 427–454. doi:10.1016/S0167-2681(98)00049-3.
Arrow, K. (1962). Economic welfare and the allocation of resources for invention. In R. Nelson (Ed.), The rate and direction of inventive activity. Princeton, NJ: Princeton University Press.
Audretsch, D. B., Keilbach, M., & Lehmann, E. E. (2005). Entrepreneurship and economic growth. London: Oxford University Press.
Audretsch, D. B., & Lehmann, E. E. (2005a). Does the knowledge spillover theory of entrepreneurship hold for regions? Research Policy, 34(8), 1191–1202. doi:10.1016/j.respol.2005.03.012.
Audretsch, D. B., & Lehmann, E. E. (2005b). Mansfield’s missing link: The impact of knowledge spillovers on firm growth. The Journal of Technology Transfer, 30(1–2), 207–210. doi:10.1007/s10961-004-4367-6.
Audretsch, D. B., & Lehmann, E. E. (2006). Entrepreneurial access and absorption of knowledge spillovers: Strategic board and managerial composition for competitive advantage. Journal of Small Business Management, 44(2), 155–166. doi:10.1111/j.1540-627X.2006.00161.x.
Audretsch, D. B., Lehmann, E. E., & Warning, S. (2004). University spillovers: Does the kind of knowledge matters? Industry and Innovation, 11(3), 193–205. doi:10.1080/1366271042000265375.
Audretsch, D. B., & Stephan, P. E. (1996). Company-scientist locational links: The case of biotechnology. The American Economic Review, 86(3), 641–652.
Bade, F., & Nerlinger, E. A. (2000). The spatial distribution of new technology-based firms. Papers in Regional Science, 79(2), 155–176. doi:10.1007/s101100050041.
Barringer, B. R., Jones, F. F., & Neubaum, D. O. (2005). A quantitative content analysis of the characteristics of rapid-growth firms and their founders. Journal of Business Venturing, 20(5), 663–687. doi:10.1016/j.jbusvent.2004.03.004.
Bertoni, F., Colombo, M. G., & Grilli, L. (2007). Venture capital financing and the growth of new technology-based firms: A longitudinal analysis. Working paper.
Birley, S. (1984). Finding the new firm. Proceedings of the Academy of Management Meetings, 47, 64–68.
Blundell, R., & Bond, S. (1998). Initial conditions and moment conditions in dynamic panel data models. Journal of Econometrics, 87(1), 115–143. doi:10.1016/S0304-4076(98)00009-8.
Bond, S. (2002). Dynamic panel data models: A guide to micro data methods and practice. Portuguese Economic Journal, 1(2), 141–162. doi:10.1007/s10258-002-0009-9.
Breno, E., Fava, G. A., Guardabasso, V., & Stefanelli, M. (2002). La ricerca scientifica nelle università italiane. Una prima analisi delle citazioni della banca dati ISI (Scientific research in Italian Universities. A first analysis of citations from ISI database). CRUI: Roma.
Caves, R. (1998). Industrial organization and new findings on the turnover and mobility of firms. Journal of Economic Literature, 36(4), 1947–1982.
Cockburn, I., & Henderson, R. (1998). Absorptive capacity, coauthoring behavior, and the organization of research in drug discovery. The Journal of Industrial Economics, 46(2), 157–182.
Cohen, W. M., Florida, R., Randazzese, L., & Walsh, J. (1998). Industry and the academy: Uneasy partners in the cause of technological advance. In R. G. Noll (Ed.), Challenges to research universities (ch. 7). Washington, DC: Brookings Institute Press.
Cohen, W. M., & Levinthal, D. A. (1989). Innovation and learning: The two faces of R&D. The Economic Journal, 99(397), 569–596. doi:10.2307/2233763.
Cohen, W. M., & Levinthal, D. A. (1990). Absorptive capacity: A new perspective on learning and innovation. Administrative Science Quarterly, 35(1), 128–152. doi:10.2307/2393553.
Colombo, M. G., & Delmastro, M. (1999). Some stylized facts on organisation and its evolution. Journal of Economic Behavior & Organization, 40(3), 252–274. doi:10.1016/S0167-2681(99)00067-0.
Colombo, M. G., & Grilli, L. (2005). Founders’ human capital and the growth of new technology-based firms: A competence-based view. Research Policy, 34(6), 795–816. doi:10.1016/j.respol.2005.03.010.
Colombo, M. G., & Piva, E. (2008a). Strenghts and weaknesses of academic start-ups: A conceptual model. IEEE Transactions on Engineering Management, 55(1), 37–49. doi:10.1109/TEM.2007.912807.
Colombo, M. G., & Piva, E. (2008b). Firms’ genetic characteristics, competence enlarging strategies and performances: A comparison between academic and non-academic high-tech start-ups. Working paper.
Dasgupta, P., & David, P. (1994). Towards a new economics of science. Research Policy, 23(5), 487–521. doi:10.1016/0048-7333(94)01002-1.
Del Barrio-Castro, T., & García-Quevedo, J. (2005). Effects of university research on the geography of innovation. Regional Studies, 39(9), 1217–1229. doi:10.1080/00343400500389992.
Di Gregorio, D., & Shane, S. (2003). Why do some universities generate more start-ups than others? Research Policy, 32(2), 209–227. doi:10.1016/S0048-7333(02)00097-5.
Drucker, J., & Goldstein, H. A. (2007). Assessing the regional economic development impacts of universities: A review of current approaches. International Regional Science Review, 30(1), 20–46. doi:10.1177/0160017606296731.
Evans, D. S. (1987a). The relationship between firm growth, size, and age: Estimates for 100 manufacturing industries. The Journal of Industrial Economics, 35(4), 567–581. doi:10.2307/2098588.
Evans, D. S. (1987b). Tests of alternative theories of firm growth. The Journal of Political Economy, 95(4), 657–674. doi:10.1086/261480.
Feeser, H. R., & Willard, G. E. (1990). Founding strategy and performance: A comparison of high and low growth high tech firms. Strategic Management Journal, 11(2), 87–98. doi:10.1002/smj.4250110202.
Feldman, M. P., & Florida, R. (1994). The geographic sources of innovation: Technological infrastructure and product innovation in the United States. Annals of the Association of American Geographers, 84(2), 210–229. doi:10.1111/j.1467-8306.1994.tb01735.x.
Fischer, E., & Reuber, R. (2003). Support for rapid growth firms: A comparison of the views of founders, government policy makers and private sector resource providers. Journal of Small Business Management, 41(4), 346–365.
Fischer, M. M., & Varga, A. (2003). Spatial knowledge spillovers and university research: Evidence from Austria. The Annals of Regional Science, 37(2), 303–322. doi:10.1007/s001680200115.
Gimeno, J., Folta, T., Cooper, A., & Woo, C. (1997). Survival of the fittest? Entrepreneurial human capital and the persistence of underperforming firms. Administrative Science Quarterly, 42(4), 750–783. doi:10.2307/2393656.
Goldstein, H. A., & Drucker, J. (2006). The economic development impacts of universities on regions: Do size and distance matter? Economic Development Quarterly, 20(1), 22–43. doi:10.1177/0891242405283387.
Goldstein, H. A., & Renault, C. S. (2004). Contributions of universities to regional economic development: A quasi-experimental approach. Regional Studies, 38(7), 733–746. doi:10.1080/0034340042000265232.
Hart, P. E., & Oulton, N. (1996). Growth and size of firms. The Economic Journal, 106(438), 1242–1252. doi:10.2307/2235518.
Jaffe, A. B. (1989). Real effects of academic research. The American Economic Review, 79(5), 957–970.
Jaffe, A. B., Trajtenberg, M., & Henderson, R. (1993). Geographic localization of knowledge spillovers as evidenced by patent citations. The Quarterly Journal of Economics, 108(3), 577–598. doi:10.2307/2118401.
Klepper, S. (2007). Disagreements, spinoffs, and the evolution of Detroit as the capital of the U.S. automobile industry. Management Science, 53(4), 616–631. doi:10.1287/mnsc.1060.0683.
Lim, K. (2000). The many faces of absorptive capacity: Spillovers of copper interconnect technology for semiconductor chips. Mimeo: MIT.
Little, A. D. (1977). New Technology-based firms in the United Kingdom and the federal Republic of Germany. London: Wilton House.
Moulton, B. R. (1990). An illustration of a pitfall in estimating the effects of aggregate variables on micro units. The Review of Economics and Statistics, 72(2), 334–338. doi:10.2307/2109724.
Mowery, D. C., & Ziedonis, A. A. (2001). The geographic reach of market and non-market channels of technology transfer: Comparing citations and licenses of university patents. NBER Working Paper 8568.
Murray, F. (2004). The role of academic inventors in entrepreneurial firms: sharing the laboratory life. Research Policy, 33(4), 643–659. doi:10.1016/j.respol.2004.01.013.
Nelson, R. (1959). The simple economics of basic scientific research. The Journal of Political Economy, 67(3), 297–306. doi:10.1086/258177.
O’Shea, R. P., Allen, T. J., Chevalier, A., & Roche, F. (2005). Entrepreneurial orientation, technology transfer and spin-off performance of US universities. Research Policy, 34(7), 994–1009. doi:10.1016/j.respol.2005.05.011.
Piergiovanni, R., Santarelli, E., & Vivarelli, M. (1997). From which source do small firms derive their innovative inputs? Some evidence from Italian industry. Review of Industrial Organization, 12(2), 243–258. doi:10.1023/A:1007781501147.
Powers, J. B., & McDougall, P. P. (2005). University start-up formation and technology licensing with firms that go public: A resource-based view of academic entrepreneurship. Journal of Business Venturing, 20(3), 291–311. doi:10.1016/j.jbusvent.2003.12.008.
Roberts, E. B. (1991). High tech entrepreneurs: Lessons from MIT and beyond. New York: Oxford University Press.
Roberts, E. B., & Malone, D. (1996). Policies and structures for spinning off new companies from research and development organizations. R & D Management, 26(1), 17–48. doi:10.1111/j.1467-9310.1996.tb00927.x.
Rodríguez-Pose, A., & Refolo, M. C. (2003). The link between local production systems and public and university research in Italy. Environment & Planning A, 35(8), 1477–1492. doi:10.1068/a35297.
Rosenberg, N., & Nelson, R. (1994). American universities and technical advance in industry. Research Policy, 23(3), 323–348. doi:10.1016/0048-7333(94)90042-6.
Stern, S. (2004). Do scientists pay to be scientists? Management Science, 50(6), 835–853. doi:10.1287/mnsc.1040.0241.
Storey, D. J. (1994). Understanding the small business sector. London: Thomson Learning.
Stuart, T. E., Ozdemir, S. Z., & Ding, W. W. (2007). Vertical alliance networks: The case of university-biotechnology-pharmaceutical alliance chains. Research Policy, 36(4), 477–498. doi:10.1016/j.respol.2007.02.016.
Sutton, J. (1997). Gibrat’s legacy. Journal of Economic Literature, 35(1), 40–59.
Varga, A. (2000). Local academic knowledge transfers and the concentration of economic activity. Journal of Regional Science, 40(2), 289–309. doi:10.1111/0022-4146.00175.
Wright, M., Birley, S., & Mosey, S. (2004). Entrepreneurship and university technology transfer. The Journal of Technology Transfer, 29(3–4), 235–246. doi:10.1023/B:JOTT.0000034121.02507.f3.
Zahra, S. A., & George, G. (2002). Absorptive capacity: A review, reconceptualization, and extension. Academy of Management Review, 27(2), 185–203. doi:10.2307/4134351.
Zucker, L. G., Darby, M. R., & Armstrong, J. S. (1998). Intellectual capital and the firm: The technology of geographically localized knowledge spillovers. Economic Inquiry, 36, 65–86.
Zucker, L. G., Darby, M. R., & Armstrong, J. S. (2000). University science, venture capital and the performance of U.S. biotechnology firms. Mimeo, Los Angeles: University of California.
Zucker, L. G., Darby, M. R., & Brewer, M. (1999). Intellectual capital and the birth of U.S. biotechnology enterprises. The American Economic Review, 88(1), 290–306.