Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

Affolter, 1990, DNA binding properties of the purified Antennapedia homeodomain, 87, 4093 Aggarwal, 1988, Recognition of a DNA operator by the repressor of phage 434: a view at high resolution, Science, 242, 899, 10.1126/science.3187531 Brünger, 1990 Brünger, 1987, Crystallographic R factor refinement by molecular dynamics, Science, 235, 458, 10.1126/science.235.4787.458 Burley, 1985, Aromatic-aromatic interactions: a mechanism of protein structure stabilization, Science, 229, 23, 10.1126/science.3892686 Dickerson, 1981, Structure of a B-DNA dodecamer. II. Influence of base sequence on helix structure, J. Mol. Biol., 149, 761, 10.1016/0022-2836(81)90357-0 Hanes, 1989, DNA specificity of the Bicoid activator protein is determined by homeodomain recognition helix residue 9, Cell, 57, 1275, 10.1016/0092-8674(89)90063-9 Herr, 1988, The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products, Genes Dev., 2, 1513, 10.1101/gad.2.12a.1513 Ingraham, 1990, The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions, Cell, 61, 1021, 10.1016/0092-8674(90)90067-O Johnson, 1980, Mechanism of action of λ-cro protein Jordan, 1988, Structure of the lambda complex at 2.5 Å resolution: details of the repressor-operator interactions, Science, 242, 893, 10.1126/science.3187530 Jordan, 1985, Systematic variation in DNA length yields highly ordered repressor-operator cocrystals, Science, 230, 1383, 10.1126/science.3906896 Kornberg, 1981, engrailed: a gene controlling compartment and segment formation in Drosophila, 78, 1095 Laughon, 1984, Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins, Nature, 310, 25, 10.1038/310025a0 Liu, 1990, Crystallization and preliminary diffraction studies of the engrailed homeodomain and of an engrailed homeodomain-DNA complex, Biochem. Biophys. Res. Commun., 171, 257, 10.1016/0006-291X(90)91385-6 Otwinowski, 1988, Crystal structure of trp repressor/operator complex at atomic resolution, Nature, 335, 321, 10.1038/335321a0 Pabo, 1984, Protein-DNA recognition, Annu. Rev. Biochem., 53, 293, 10.1146/annurev.bi.53.070184.001453 Pabo, 1990, Conserved residues make similar contacts in two repressor-operator complexes, Science, 247, 1210, 10.1126/science.2315694 Poole, 1985, The engrailed locus of Drosophila: structural analysis of an embryonic transcript, Cell, 40, 37, 10.1016/0092-8674(85)90306-X Qian, 1989, The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors, Cell, 59, 573, 10.1016/0092-8674(89)90040-8 Rossmann, 1980, Three-dimensional coordinates from stereodiagrams of molecular structures, Acta Crystallogr, B36, 819, 10.1107/S056774088000461X Rould, 1989, Structure of E. coll glutaminyl-tRNA synthetase complexed with tRNAGln and ATP at 2.8 Å resolution, Science, 246, 1135, 10.1126/science.2479982 Scott, 1989, The structure and function of the homeodomain, Biochim. Biophys. Acta, 989, 25 Seeman, 1976, Sequence-specific recognition of double helical nucleic acids by proteins, 73, 804 Shepard, 1984, Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins, Nature, 310, 70, 10.1038/310070a0 Sluka, 1990, Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinase, Biochemistry, 29, 6551, 10.1021/bi00480a002 Staacke, 1990, How Trp repressor binds to its operator, EMBO J., 9, 1963, 10.1002/j.1460-2075.1990.tb08324.x Treisman, 1989, A single amino acid can determine the DNA binding specificity of homeodomain proteins, Cell, 59, 553, 10.1016/0092-8674(89)90038-X Wang, 1985, Resolution of phase ambiguity in macromolecular crystallography, Meth. Enzymol., 115, 90, 10.1016/0076-6879(85)15009-3 Wang, 1979, Helical repeat of DNA in solution, 76, 200