Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy

Journal of Controlled Release - Tập 168 - Trang 142-150 - 2013
Li Li1, Timo L.M. ten Hagen1, Martin Hossann2,3, Regine Süss4, Gerard C. van Rhoon5, Alexander M.M. Eggermont1,6, Dieter Haemmerich7, Gerben A. Koning1
1Laboratory Experimental Surgical Oncology, Section Surgical Oncology, Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
2Department of Internal Medicine III, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany
3CCG Tumor Therapy Through Hyperthermia, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany
4Department of Pharmaceutical Technology and Biopharmacy, Albert-Ludwigs University, Freiburg, Germany
5Unit Hyperthermia, Department of Radiotherapy, Erasmus Medical Center — Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
6Institut de Cancérologie Gustave Roussy, Paris, France
7Medical University of South Carolina, Charleston, USA

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Journal of Controlled Release

Tập 168

142-150

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