Brain Tumor Tropism of Transplanted Human Neural Stem Cells Is Induced by Vascular Endothelial Growth Factor

Kleihues, 2000 Aboody, 2000, From the cover: neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas, Proc Natl Acad Sci USA, 97, 12846, 10.1073/pnas.97.23.12846 Benedetti, 2000, Gene therapy of experimental brain tumors using neural progenitor cells, Nat Med, 6, 447, 10.1038/74710 Ehtesham, 2002, The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma, Cancer Res, 62, 5657 Staflin, 2004, Neural progenitor cell lines inhibit rat tumor growth in vivo, Cancer Res, 64, 5347, 10.1158/0008-5472.CAN-03-1246 Brown, 2003, Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin, Hum Gene Ther, 14, 1777, 10.1089/104303403322611782 Song, 2001, The cell biology of neuronal navigation, Nat Cell Biol, 3, 8E1, 10.1038/35060164 Harrigan, 2003, Angiogenic factors in the central nervous system, Neurosurgery, 53, 639, 10.1227/01.NEU.0000079575.09923.59 Park, 2002, Global gene and cell replacement strategies via stem cells, Gene Ther, 9, 613, 10.1038/sj.gt.3301721 Carmeliet, 2002, Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders, Semin Cell Dev Biol, 13, 39, 10.1006/scdb.2001.0290 Jeong, 2003, Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage, Stroke, 34, 2258, 10.1161/01.STR.0000083698.20199.1F Cho, 2002, Human neural stem cells: electrophysiological properties of voltage-gated ion channels, Neuroreport, 13, 1447, 10.1097/00001756-200208070-00020 Schmidt, 1999, Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis, Int J Cancer, 84, 10, 10.1002/(SICI)1097-0215(19990219)84:1<10::AID-IJC3>3.0.CO;2-L Schmidt, 2004, Antiangiogenic therapy by local intracerebral microinfusion improves treatment efficiency and sur vival in an orthotopic human glioblastoma model, Clin Cancer Res, 10, 1255, 10.1158/1078-0432.CCR-03-0052 Iman, 1979, Technometrics, 21, 499, 10.1080/00401706.1979.10489820 Louissaint, 2002, Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain, Neuron, 34, 945, 10.1016/S0896-6273(02)00722-5 Monje, 2002, Irradiation induces neural precursor-cell dysfunction, Nat Med, 8, 955, 10.1038/nm749 Zhang, 2003, VEGF is a chemoattractant for FGF-2-stimulated neural progenitors, J Cell Biol, 163, 1375, 10.1083/jcb.200308040 Ferrara, 2003, The biology of VEGF and its receptors, Nat Med, 9, 669, 10.1038/nm0603-669 Ehtesham, 2004, Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4, Neoplasia, 6, 287, 10.1593/neo.03427