Microbiota-Derived Indole Metabolites Promote Human and Murine Intestinal Homeostasis through Regulation of Interleukin-10 Receptor
Tài liệu tham khảo
Lozupone, 2012, Diversity, stability and resilience of the human gut microbiota, Nature, 489, 220, 10.1038/nature11550
Muniz, 2012, Intestinal antimicrobial peptides during homeostasis, infection, and disease, Front Immunol, 3, 310, 10.3389/fimmu.2012.00310
Xavier, 2007, Unravelling the pathogenesis of inflammatory bowel disease, Nature, 448, 427, 10.1038/nature06005
Huttenhower, 2014, Inflammatory bowel disease as a model for translating the microbiome, Immunity, 40, 843, 10.1016/j.immuni.2014.05.013
Frank, 2007, Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases, Proc Natl Acad Sci U S A, 104, 13780, 10.1073/pnas.0706625104
Engelhardt, 2014, IL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies, and IL-10 polymorphisms, Curr Top Microbiol Immunol, 380, 1
Kominsky, 2014, IFN-gamma-mediated induction of an apical IL-10 receptor on polarized intestinal epithelia, J Immunol, 192, 1267, 10.4049/jimmunol.1301757
Colgan, 1994, Interferon-γ induces a surface phenotype switch in intestinal epithelia: downregulation of ion transport and upregulation of immune accessory ligands, Am J Physiol, 267, C402, 10.1152/ajpcell.1994.267.2.C402
Kuhn, 1993, Interleukin-10-deficient mice develop chronic enterocolitis, Cell, 75, 263, 10.1016/0092-8674(93)80068-P
Chaudhry, 2011, Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation, Immunity, 34, 566, 10.1016/j.immuni.2011.03.018
Wikoff, 2009, Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites, Proc Natl Acad Sci U S A, 106, 3698, 10.1073/pnas.0812874106
Zelante, 2013, Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22, Immunity, 39, 372, 10.1016/j.immuni.2013.08.003
Hubbard, 2015, Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles, Sci Rep, 5, 12689, 10.1038/srep12689
Mascanfroni, 2015, Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-alpha, Nat Med, 21, 638, 10.1038/nm.3868
Kimura, 2008, Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells, Proc Natl Acad Sci U S A, 105, 9721, 10.1073/pnas.0804231105
Monteleone, 2011, Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract, Gastroenterology, 141, 237, 10.1053/j.gastro.2011.04.007
Gaitanis, 2008, AhR ligands, malassezin, and indolo[3,2-b]carbazole are selectively produced by Malassezia furfur strains isolated from seborrheic dermatitis, J Invest Dermatol, 128, 1620, 10.1038/sj.jid.5701252
Vlachos, 2012, Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells, Br J Dermatol, 167, 496, 10.1111/j.1365-2133.2012.11014.x
McCracken, 2011, Generating human intestinal tissue from pluripotent stem cells in vitro, Nat Protoc, 6, 1920, 10.1038/nprot.2011.410
Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res, 29, e45, 10.1093/nar/29.9.e45
Albrecht, 2014, Metabolite profiling reveals new insights into the regulation of serum urate in humans, Metabolomics, 10, 141, 10.1007/s11306-013-0565-2
Dieleman, 1998, Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines, Clin Exp Immunol, 114, 385, 10.1046/j.1365-2249.1998.00728.x
Lanis, 2017, Tryptophan metabolite activation of the aryl hydrocarbon receptor regulates IL-10 receptor expression on intestinal epithelia, Mucosal Immunol, 10, 1133, 10.1038/mi.2016.133
Spence, 2011, Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro, Nature, 470, 105, 10.1038/nature09691
Suzuki, 2001, CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation, J Exp Med, 193, 471, 10.1084/jem.193.4.471
Hubbard, 2015, Indole and tryptophan metabolism: endogenous and dietary routes to Ah receptor activation, Drug Metab Dispos, 43, 1522, 10.1124/dmd.115.064246
Lo, 2012, High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq, Toxicol Sci, 130, 349, 10.1093/toxsci/kfs253
Mathieu, 2001, Aromatic hydrocarbon receptor (AhR).AhR nuclear translocator- and p53-mediated induction of the murine multidrug resistance mdr1 gene by 3-methylcholanthrene and benzo(a)pyrene in hepatoma cells, J Biol Chem, 276, 4819, 10.1074/jbc.M008495200
Lee, 2015, Roles of indole as an interspecies and interkingdom signaling molecule, Trends Microbiol, 23, 707, 10.1016/j.tim.2015.08.001
Manichanh, 2012, The gut microbiota in IBD, Nat Rev Gastroenterol Hepatol, 9, 599, 10.1038/nrgastro.2012.152
Butto, 2016, Dysbiosis in intestinal inflammation: cause or consequence, Int J Med Microbiol, 306, 302, 10.1016/j.ijmm.2016.02.010
Sartor, 2008, Microbial influences in inflammatory bowel diseases, Gastroenterology, 134, 577, 10.1053/j.gastro.2007.11.059
Kominsky, 2011, An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling, J Immunol, 186, 6505, 10.4049/jimmunol.1002805
Newton, 1964, Catalytic properties of tryptophanase, a multifunctional pyridoxal phosphate enzyme, Proc Natl Acad Sci U S A, 51, 382, 10.1073/pnas.51.3.382
Hopkins, 1903, A contribution to the chemistry of proteids: part II. The constitution of tryptophane, and the action of bacteria upon it, J Physiol, 29, 451, 10.1113/jphysiol.1903.sp000968
Lee, 2010, Indole as an intercellular signal in microbial communities, FEMS Microbiol Rev, 34, 426, 10.1111/j.1574-6976.2009.00204.x
Martin, 1998, The tryptophanase gene cluster of Haemophilus influenzae type b: evidence for horizontal gene transfer, J Bacteriol, 180, 107, 10.1128/JB.180.1.107-118.1998
De Preter, 2015, Faecal metabolite profiling identifies medium-chain fatty acids as discriminating compounds in IBD, Gut, 64, 447, 10.1136/gutjnl-2013-306423
Wlodarska, 2017, Indoleacrylic acid produced by commensal peptostreptococcus species suppresses inflammation, Cell Host Microbe, 22, 25, 10.1016/j.chom.2017.06.007
Machiels, 2014, A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis, Gut, 63, 1275, 10.1136/gutjnl-2013-304833
Eeckhaut, 2013, Butyricicoccus pullicaecorum in inflammatory bowel disease, Gut, 62, 1745, 10.1136/gutjnl-2012-303611
Sokol, 2009, Low counts of Faecalibacterium prausnitzii in colitis microbiota, Inflamm Bowel Dis, 15, 1183, 10.1002/ibd.20903
Shimada, 2013, Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon, PLoS One, 8, e80604, 10.1371/journal.pone.0080604
Venkatesh, 2014, Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4, Immunity, 41, 296, 10.1016/j.immuni.2014.06.014
Cheng, 2012, Pregnane X receptor as a target for treatment of inflammatory bowel disorders, Trends Pharmacol Sci, 33, 323, 10.1016/j.tips.2012.03.003
Devlin, 2016, Modulation of a circulating uremic solute via rational genetic manipulation of the gut microbiota, Cell Host Microbe, 20, 709, 10.1016/j.chom.2016.10.021
Heath-Pagliuso, 1998, Activation of the Ah receptor by tryptophan and tryptophan metabolites, Biochemistry, 37, 11508, 10.1021/bi980087p
Jin, 2014, Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities, Mol Pharmacol, 85, 777, 10.1124/mol.113.091165
Li, 2011, Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation, Cell, 147, 629, 10.1016/j.cell.2011.09.025
Cervantes-Barragan, 2017, Lactobacillus reuteri induces gut intraepithelial CD4+CD8alphaalpha+ T cells, Science, 357, 806, 10.1126/science.aah5825
Bessede, 2014, Aryl hydrocarbon receptor control of a disease tolerance defence pathway, Nature, 511, 184, 10.1038/nature13323
Belkaid, 2014, Role of the microbiota in immunity and inflammation, Cell, 157, 121, 10.1016/j.cell.2014.03.011