Enhancing the copy number of Ldrab6 gene in Leishmania donovani parasites mediates drug resistance through drug‐thiol conjugate dependent multidrug resistance protein A (MRPA)

Acta Tropica - Tập 199 - Trang 105158 - 2019
Indira Singh Chauhan1, G. Subba Rao2, Neeloo Singh1
1Biochemistry Division, CSIR-Central Drug Research Institute, Jankipuram Extension, Sitapur Road, Lucknow 226031, India
2Global Biotechnology Resource Center, 145 Rosewood Drive, Streamwood, IL 60107, USA

Tài liệu tham khảo

Chauhan, 2015, Evolutionary comparison of prenylation pathway in kinetoplastid Leishmania and its sister Leptomonas, BMC Evol. Biol., 15, 10.1186/s12862-015-0538-3 Chauhan, 2018, Chemoprevention of Leishmaniasis: in-vitro antiparasitic activity of dibenzalacetone, a synthetic curcumin analog leads to apoptotic cell death in Leishmania donovani, Parasitol. Int., 67, 627, 10.1016/j.parint.2018.06.004 de Menezes, 2015, Advances in development of new treatment for leishmaniasis, BioMed. Res. Int., 2015, 10.1155/2015/815023 Essodaı̈gui, 1999, Energy-dependent efflux from Leishmania promastigotes of substrates of the mammalian multidrug resistance pumps, Mol. Biochem. Parasitol., 100, 73, 10.1016/S0166-6851(99)00036-5 Fan, 2015, Rab25 is responsible for phosphoinositide 3-kinase/AKT-mediated cisplatin resistance in human epithelial ovarian cancer cells, Mol. Med. Rep., 11, 2173, 10.3892/mmr.2014.2963 Ferrándiz‐Huertas, 2011, Rab4 interacts with the human P‐glycoprotein and modulates its surface expression in multidrug resistant K562 cells, Int. J. Cancer, 128, 192, 10.1002/ijc.25310 Fu, 2013, Where is it and how does it get there–intracellular localization and traffic of P-glycoprotein, Front. Oncology, 3, 10.3389/fonc.2013.00321 Laban, 1989, Transfection of Leishmania enriettii and expression of chloramphenicol acetyltransferase gene, Proc. Nat. Acad. Sci. U.S.A., 86, 9119, 10.1073/pnas.86.23.9119 Lage, 2003, ABC-transporters: implications on drug resistance from microorganisms to human cancers, Int. J. Antimicrob. Agent, 22, 188, 10.1016/S0924-8579(03)00203-6 Loiseau, 2011, Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistance, Parasite, 18, 115, 10.1051/parasite/2011182115 Shan, 2000, Rab6c, a new member of the Rab gene family, is involved in drug resistance in MCF7/AdrR cells, Gene, 257, 67, 10.1016/S0378-1119(00)00395-4 Shan, 2002, WTH3, a new member of the Rab6 gene family, and multidrug resistance, Biochim. Biophysic. Acta -Mol. Cell Res., 1589, 112, 10.1016/S0167-4889(02)00164-7 Shen, 2012, RAB8 enhances TMEM205-mediated cisplatin resistance, Pharm. Res., 29, 643, 10.1007/s11095-011-0562-y Singh, 2006, Drug resistance mechanisms in clinical isolates of Leishmania donovani, Indian J. Med. Res., 123, 411 Singh, 2007, Differential gene expression analysis in antimony-unresponsive Indian kala azar (visceral leishmaniasis) clinical isolates by DNA microarray, Parasitology, 134, 777, 10.1017/S0031182007002284 Singh, 2014, The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India, Parasit. Vectors, 7, 10.1186/s13071-014-0596-1 Sundar, 2015, An update on pharmacotherapy for leishmaniasis, Exp. Op. Pharmacother., 16, 237, 10.1517/14656566.2015.973850 Sundar, 2007, Injectable paromomycin for visceral leishmaniasis in India, N. Eng. J. Med., 356, 2571, 10.1056/NEJMoa066536 Sundar, 2005, Perspectives: Availability of miltefosine for the treatment of kala-azar in India, Bull. World Health Organ., 83, 394 Wyllie, 2004, Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani, J. Biol. Chem., 279, 39925, 10.1074/jbc.M405635200