Clinical and Behavioral Outcomes for Transgender Women Engaged in HIV Care: Comparisons to Cisgender Men and Women in the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) Cohort

Springer Science and Business Media LLC - Tập 27 - Trang 2113-2130 - 2023
Sari L. Reisner1,2,3,4, Bridget M. Whitney5, Heidi M. Crane5, Kenneth H. Mayer4, Chris Grasso4, Robin M. Nance5, Tonia Poteat6, W. Chris Mathews7, Katerina Christopoulos8, Michael J. Mugavero9, Geetanjali Chander10, Joseph J. Eron11, Mari M. Kitahata5, Joseph A. C. Delaney12, Rob J. Fredericksen5
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, USA
2Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, USA
3General Pediatrics, Harvard Medical School/Boston Children’s Hospital, Boston, USA
4The Fenway Institute, Fenway Health, Boston, USA
5Department of Medicine, University of Washington, Seattle, USA
6Department of Social Medicine, University of North Carolina, Chapel Hill, USA
7Department of Medicine, University of California, San Diego, USA
8Department of Medicine, University of California, San Francisco, USA
9Department of Medicine, University of Alabama, Birmingham USA
10Department of Medicine, Johns Hopkins University, Baltimore, USA
11Department of Medicine, University of North Carolina, Chapel Hill, USA
12College of Pharmacy, University of Manitoba, Winnipeg, Canada

Tóm tắt

Describe health of transgender women (TW) with HIV vs. cisgender men and women (CM, CW) in a U.S. HIV care cohort. Data were from Centers for AIDS Research Network of Integrated Clinical Systems (CNICS), 2005–2022. TW were identified using clinical data/identity measures. PWH (n = 1285) were included in analyses (275 TW, 547 CM, 463 CW). Cross-sectional multivariable analyses compared HIV outcomes/co-morbidities between TW/CM and TW/CW, and adjusted odds ratios (aOR) and 95% confidence intervals (95% CI) were estimated. TW had poorer adherence (> 90% adherent; aOR 0.57; 95%CI 0.38, 0.87) and were more likely to miss ≥ 3 visits in the past year than CM (aOR 1.50, 95%CI 1.06, 2.10); indicated more anxiety compared to both CM and CW (p ≤ 0.001, p = 0.02); hepatitis C infection (p = 0.03) and past-year/lifetime substance treatment (p = 0.004/p = 0.001) compared to CM; and substance use relative to CW. TW with HIV differed in HIV clinical outcomes and co-morbidities from CM and CW.

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Springer Science and Business Media LLC

Tập 27

2113-2130

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