Alkylation of 4-(phenylthio)-1H-pyrazol-5-ols with methyl bromoacetate

Russian Journal of General Chemistry - Tập 87 - Trang 231-238 - 2017
R. N. Vydzhak1, S. Ya. Panchishin1, V. S. Brovarets1
1Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine

Tóm tắt

Alkylation of 4-(phenylthio)-1H-pyrazol-5-ols with methyl bromoacetate has afforded a series of phenyl pyrazolyl sulfides which have been oxidized into sulfones. The resulting esters have been hydrolyzed into the corresponding acids. The synthesized compounds potentially exhibit biological activity.

Tài liệu tham khảo

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