Chemical stability of prostacyclin (PGI2) in aqueous solutions

Moncada, 1976, An Enzyme Isolated from Arteries Transforms Prostaglandin Endoperoxides to an Unstable Substance that Inhibits Platelet Aggregation, Nature, 263, 663, 10.1038/263663a0 Johnson, 1976, The Chemical Structure of Prostacyclin X (prostacyclin), Prostaglandin, 12, 915, 10.1016/0090-6980(76)90126-X 1976, C&EN, 17 Marx, 1977, Blood Clotting: The Role of the Prostaglandins, Science, 196, 1072, 10.1126/science.196.4294.1072 Perrin, 1963, Buffers of Low Ionic Strength for Spectrophotometric pK Determinations, Austr. J. Chem., 16, 572, 10.1071/CH9630572 Morozowich, 1975, Resolution of Prostaglandin p-Nitrophenacyl Esters by Liquid Chromatography and Conditions for Rapid, Quantitative p-Nitrophenacylation, Prostaglandins, 10, 19, 10.1016/S0090-6980(75)80060-8 Frost, 1961, Kinetics and Mechanism, 186 Kresge, 1971, Vinyl Ether Hydrolysis, 93, 413 Kresge, 1967, The Hydrolysis of Ethyl Vinyl Ether, 53 Okuyama, 1976, Acid-Catalyzed Hydrolysis of Alkyl Vinyl and Propenyl Sulfides, Tetrah., 32, 2249, 10.1016/0040-4020(76)85140-X Kankaanperä, 1967, Relative Stabilities of Endo-Exo Isomeric Furan Derivatives and the Kinetics of Their Cleavage in Acid Solutions, Acta. Chem. Scand., 21, 2487, 10.3891/acta.chem.scand.21-2487 Jencks, 1969, Catalysis in Chemistry and Enzymology, 170