Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide

DNA Repair - Tập 7 - Trang 1202-1212 - 2008
Anne Lagerqvist1, Daniel Håkansson1, Gabriela Prochazka2, Cecilia Lundin2, Kristian Dreij3, Dan Segerbäck2, Bengt Jernström3, Margareta Törnqvist4, Albrecht Seidel5, Klaus Erixon1, Dag Jenssen1
1Department of Genetics, Microbiology and Toxicology (GMT), Arrhenius Laboratories of Natural Sciences, Stockholm University, S-106 91 Stockholm, Sweden
2Department of Biosciences and Nutrition, Novum, Karolinska Institute, S-141 57 Huddinge, Sweden
3The Institute for Environmental Medicine (IMM), Karolinska Institute, S-171 77 Stockholm, Sweden
4Department of Environmental Chemistry, Arrhenius Laboratories of Natural Sciences, Stockholm University, S-106 91 Stockholm, Sweden
5Biochemical Institute for Environmental Carcinogens, Lurup 4, D-22927 Grosshansdorf, Germany

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