Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy

Molecular Cell - Tập 66 - Trang 684-697.e9 - 2017
Xinjian Li1, Willie Yu2, Xu Qian1, Yan Xia1, Yanhua Zheng1, Jong-Ho Lee1, Wei Li3, Jianxin Lyu3,4, Ganesh Rao5, Xiaochun Zhang6, Chao-Nan Qian7, Steven G. Rozen2, Tao Jiang8, Zhimin Lu1,9,10
1Brain Tumor Center, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
2Program in Cancer and Stem Cell Biology, Centre for Computational Biology, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore
3Key Laboratory of Laboratory Medicine, Ministry of Education, Zhejiang Provincial Key Laboratory of Medical Genetics, Institute of Enzyme Engineering and Medical Diagnosis, College of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, China
4People’s Hospital of Hangzhou Medical College, Hangzhou 310014, China
5Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
6Qingdao University Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao 266061, China
7State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
8Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China
9Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA
10Graduate School of Biomedical Sciences, Houston, TX 77030, USA

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