Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
Tài liệu tham khảo
Brozzi, 2013, hLGDB: a database of human lysosomal genes and their regulation, Database (Oxford), 2013, bat024, 10.1093/database/bat024
Bungard, 2010, Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation, Science, 329, 1201, 10.1126/science.1191241
Cai, 2011, Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes, Mol. Cell, 42, 426, 10.1016/j.molcel.2011.05.004
Comerford, 2014, Acetate dependence of tumors, Cell, 159, 1591, 10.1016/j.cell.2014.11.020
Cunningham, 2015, Ensembl 2015, Nucleic Acids Res., 43, D662, 10.1093/nar/gku1010
Dyballa, 2009, Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels, J. Vis. Exp., 1431
Fang, 2007, Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity, J. Biol. Chem., 282, 11221, 10.1074/jbc.M611871200
Fujino, 2001, Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate, J. Biol. Chem., 276, 11420, 10.1074/jbc.M008782200
Furnari, 2007, Malignant astrocytic glioma: genetics, biology, and paths to treatment, Genes Dev., 21, 2683, 10.1101/gad.1596707
Gao, 2016, Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia, Nat. Commun., 7, 11960, 10.1038/ncomms11960
Harrow, 2012, GENCODE: the reference human genome annotation for The ENCODE Project, Genome Res., 22, 1760, 10.1101/gr.135350.111
Ingram-Smith, 2006, Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase, Biochemistry, 45, 11482, 10.1021/bi061023e
Jeon, 2012, AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress, Nature, 485, 661, 10.1038/nature11066
Ji, 2009, EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin, Mol. Cell, 36, 547, 10.1016/j.molcel.2009.09.034
Jones, 2009, Tumor suppressors and cell metabolism: a recipe for cancer growth, Genes Dev., 23, 537, 10.1101/gad.1756509
Kleinstiver, 2016, High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects, Nature, 529, 490, 10.1038/nature16526
Kurdistani, 2003, Histone acetylation and deacetylation in yeast, Nat. Rev. Mol. Cell Biol., 4, 276, 10.1038/nrm1075
Levine, 2008, Autophagy in the pathogenesis of disease, Cell, 132, 27, 10.1016/j.cell.2007.12.018
Li, 2007, The role of chromatin during transcription, Cell, 128, 707, 10.1016/j.cell.2007.01.015
Li, 2016, Mitochondria-translocated PGK1 functions as a protein kinase to coordinate glycolysis and the TCA cycle in tumorigenesis, Mol. Cell, 61, 705, 10.1016/j.molcel.2016.02.009
Lu, 1998, Activation of protein kinase C triggers its ubiquitination and degradation, Mol. Cell. Biol., 18, 839, 10.1128/MCB.18.2.839
Lyssiotis, 2014, Acetate fuels the cancer engine, Cell, 159, 1492, 10.1016/j.cell.2014.12.009
Mashimo, 2014, Acetate is a bioenergetic substrate for human glioblastoma and brain metastases, Cell, 159, 1603, 10.1016/j.cell.2014.11.025
Mizushima, 2008, Autophagy fights disease through cellular self-digestion, Nature, 451, 1069, 10.1038/nature06639
Mo, 2015, Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway, Nat. Cell Biol., 17, 500, 10.1038/ncb3111
Moussay, 2011, The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray, Autophagy, 7, 760, 10.4161/auto.7.7.15454
Nezich, 2015, MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5, J. Cell Biol., 210, 435, 10.1083/jcb.201501002
Oakhill, 2010, β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK), Proc. Natl. Acad. Sci. USA, 107, 19237, 10.1073/pnas.1009705107
Perera, 2015, Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism, Nature, 524, 361, 10.1038/nature14587
Rabinowitz, 2010, Autophagy and metabolism, Science, 330, 1344, 10.1126/science.1193497
Ramírez, 2016, deepTools2: a next generation web server for deep-sequencing data analysis, Nucleic Acids Res., 44, W160, 10.1093/nar/gkw257
Ran, 2013, Genome engineering using the CRISPR-Cas9 system, Nat. Protoc., 8, 2281, 10.1038/nprot.2013.143
Roczniak-Ferguson, 2012, The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis, Sci. Signal., 5, ra42, 10.1126/scisignal.2002790
Russell, 2014, Autophagy regulation by nutrient signaling, Cell Res., 24, 42, 10.1038/cr.2013.166
Salabei, 2014, Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis, Nat. Protoc., 9, 421, 10.1038/nprot.2014.018
Sander, 2014, CRISPR-Cas systems for editing, regulating and targeting genomes, Nat. Biotechnol., 32, 347, 10.1038/nbt.2842
Sardiello, 2009, A gene network regulating lysosomal biogenesis and function, Science, 325, 473, 10.1126/science.1174447
Schug, 2015, Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress, Cancer Cell, 27, 57, 10.1016/j.ccell.2014.12.002
Settembre, 2012, A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB, EMBO J., 31, 1095, 10.1038/emboj.2012.32
Settembre, 2013, Signals from the lysosome: a control centre for cellular clearance and energy metabolism, Nat. Rev. Mol. Cell Biol., 14, 283, 10.1038/nrm3565
Shackelford, 2009, The LKB1-AMPK pathway: metabolism and growth control in tumour suppression, Nat. Rev. Cancer, 9, 563, 10.1038/nrc2676
Shin, 2016, AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy, Nature, 534, 553, 10.1038/nature18014
Sutendra, 2014, A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation, Cell, 158, 84, 10.1016/j.cell.2014.04.046
Takahashi, 2006, Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription, Mol. Cell, 23, 207, 10.1016/j.molcel.2006.05.040
Tarasov, 2015, Sambamba: fast processing of NGS alignment formats, Bioinformatics, 31, 2032, 10.1093/bioinformatics/btv098
Watkins, 2007, Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome, J. Lipid Res., 48, 2736, 10.1194/jlr.M700378-JLR200
Wellen, 2009, ATP-citrate lyase links cellular metabolism to histone acetylation, Science, 324, 1076, 10.1126/science.1164097
Xia, 2007, c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis, Mol. Cell, 25, 219, 10.1016/j.molcel.2007.01.005
Yang, 2011, Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation, Nature, 480, 118, 10.1038/nature10598
Yang, 2012, ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect, Nat. Cell Biol., 14, 1295, 10.1038/ncb2629
Young, 2016, AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes, Genes Dev., 30, 535, 10.1101/gad.274142.115
Zhang, 2008, Model-based analysis of ChIP-Seq (MACS), Genome Biol., 9, R137, 10.1186/gb-2008-9-9-r137
