Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

Cell - Tập 181 - Trang 728-744.e21 - 2020
Theodore L. Roth1,2,3,4,5, P. Jonathan Li3,4,5, Franziska Blaeschke3,4,5, Jasper F. Nies3,4,5, Ryan Apathy3,4,5, Cody Mowery1,2,3,4,5, Ruby Yu3,4,5, Michelle L.T. Nguyen3,4,5, Youjin Lee3,4,5, Anna Truong3,4,5, Joseph Hiatt1,2,3,4,5, David Wu1,2, David N. Nguyen3,4,5,6, Daniel Goodman3,4,5, Jeffrey A. Bluestone4,7,8, Chun Jimmie Ye7,9,10,11,12,13, Kole Roybal3,9,8,14, Eric Shifrut3,4,5, Alexander Marson3,4,5,6,7,9,14
1Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA
2Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA
3Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA
4Diabetes Center, University of California San Francisco, San Francisco, CA, USA
5Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA, USA
6Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
7Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA
8Sean N. Parker Autoimmune Research Laboratory, University of California, San Francisco, San Francisco, CA, USA
9Chan Zuckerberg Biohub, San Francisco, CA, USA
10Institute for Human Genetics University of California–San Francisco San Francisco CA USA
11Division of Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
12Institute of Computational Health Sciences, University of California, San Francisco, San Francisco, CA, USA
13Department of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, CA, USA
14UCSF Helen Diller Family Comprehensive Cancer Center University of California–San Francisco San Francisco CA USA

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