Direct lung delivery of para-aminosalicylic acid by aerosol particles

Edwards, 2002, The delivery of biological agents by aerosols, Am Inst Chem Eng J, 48, 2, 10.1002/aic.690480102 Edwards, 1997, Large porous biodegradable particles for pulmonary drug delivery, Science, 276, 1868, 10.1126/science.276.5320.1868 Dunbar, 1998, Dispersion and characterization of pharmaceutical dry powder aerosols, KONA, 16, 7, 10.14356/kona.1998007 Edwards, 2002, Therapeutic aerosol bioengineering, Annu Rev Biomed Eng, 4, 93, 10.1146/annurev.bioeng.4.100101.132311 Kawaguchi, 1986, Phagocytosis of latex-particles by leukocytes 1. Dependence of phagocytosis on the size and surface-potential of particles, Biomaterials, 7, 61, 10.1016/0142-9612(86)90091-8 Krenis, 1961, Effect of size and concentration of latex particles on respiration of human blood leukocytes, Proc Soc Exp Biol Med, 107, 748, 10.3181/00379727-107-26743 Rudt, 1992, In vitro phagocytosis assay of nanoparticles and microparticles by chemiluminescence 1. Effect of analytical parameters, particle size and particle concentration, J Controlled Release, 22, 263, 10.1016/0168-3659(92)90101-V Vanbever, 1999, Sustained release of insulin from insoluble inhaled particles, Drug Dev Res, 48, 178, 10.1002/(SICI)1098-2299(199912)48:4<178::AID-DDR5>3.0.CO;2-I Flume, 2002, The rationale for aerosolized antibiotics, Pharmacotherapy, 22, 71S, 10.1592/phco.22.6.71S.33909 Sacks, 2001, Adjunctive salvage therapy with inhaled aminoglycosides for patients with persistent smear-positive pulmonary tuberculosis, Clin Infect Dis, 32, 44, 10.1086/317524 Peloquin, 1999, Once-daily and twice-daily dosing of p-aminosalicylic acid granules, Am J Respir Crit Care Med, 159, 932, 10.1164/ajrccm.159.3.9807131 O’Hara, 2000, Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis, Pharm Res, 17, 955, 10.1023/A:1007527204887 Mitnick, 2003, Community-based therapy for multiresistant tuberculosis in Lima, Peru, N Engl J Med, 348, 119, 10.1056/NEJMoa022928 Gonda, 1991, 95 Waynforth HB, Flecknell PA. Catheterisation of the jugular vein. In: Experimental and surgical technique in the rat, 2nd ed. Boston: Academic Press; 1992. Peloquin, 2001, Pharmacokinetics of para-aminosalicylic acid granules under four dosing conditions, Ann Pharmacother, 35, 1332, 10.1345/aph.1A088 Dunbar, 2002, In vitro and in vivo dose delivery characteristics of large porous particles for inhalation, Int J Pharm, 245, 179, 10.1016/S0378-5173(02)00349-6 Yew, 1999, Serum pharmacokinetics of antimicrobial drugs in patients with multidrug-resistant tuberculosis during therapy, Int J Clin Pharm Res, XIX, 65 Hatch, 1992, Comparative biochemistry of airway lining fluid