Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)

Archives of Virology - Tập 156 - Trang 1397-1413 - 2011
Jelle Matthijnssens1, Max Ciarlet2, Sarah M. McDonald3, Houssam Attoui4, Krisztián Bányai5, J. Rodney Brister6, Javier Buesa7, Mathew D. Esona8, Mary K. Estes9, Jon R. Gentsch8, Miren Iturriza-Gómara10, Reimar Johne11, Carl D. Kirkwood12, Vito Martella13, Peter P. C. Mertens4, Osamu Nakagomi14, Viviana Parreño15, Mustafizur Rahman16, Franco M. Ruggeri17, Linda J. Saif18, Norma Santos19, Andrej Steyer20, Koki Taniguchi21, John T. Patton3, Ulrich Desselberger22, Marc Van Ranst1
1Laboratory of Clinical & Epidemiological Virology, Department of Microbiology & Immunology, Rega Institute for Medical Research, University of Leuven, Leuven, Belgium
2Clinical Research and Development, Novartis Vaccines & Diagnostics, Inc, Cambridge, USA
3Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
4Vector-Borne Diseases Program, Institute for Animal Health, Surrey, UK
5Veterinary Medical Research Institute, Hungarian Academy of Sciences, Budapest, Hungary
6National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, USA.
7Department of Microbiology and Ecology, School of Medicine, University of Valencia, Valencia, Spain
8Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, USA
9Department of Molecular Virology and Microbiology and Medicine-GI, Baylor College of Medicine, Houston, USA
10Enteric Virus Unit, Virus Reference Department, Centre for Infection, Health Protection Agency, London, UK
11Federal Institute for Risk Assessment, Berlin, Germany
12Enteric Virus Research Group, Murdoch Childrens Research Institute, Royal Children’s Hospital, Parkville, Australia
13Department of Veterinary Public Health, University of Bari, Bari, Italy
14Department of Molecular Microbiology and Immunology, Nagasaki University, Nagasaki, Japan
15Instituto de Virología, CICVyA, INTA Castelar, Buenos Aires, Argentina
16Laboratory of Virology, ICDDR,B, Dhaka, Bangladesh
17Department of Veterinary Public Health & Food Safety, Istituto Superiore di Sanità, Rome, Italy
18Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, USA
19Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
20University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia
21Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Japan
22Department of Medicine, Addenbrooke’s Hospital, University of Cambridge, Cambridge, UK

Tóm tắt

In April 2008, a nucleotide-sequence-based, complete genome classification system was developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of the 11 genome segments of a particular RV strain according to established nucleotide percent cutoff values. Using this approach, the genome of individual RV strains are given the complete descriptor of Gx-P[x]-Ix-Rx-Cx-Mx-Ax-Nx-Tx-Ex-Hx. The Rotavirus Classification Working Group (RCWG) was formed by scientists in the field to maintain, evaluate and develop the RV genotype classification system, in particular to aid in the designation of new genotypes. Since its conception, the group has ratified 51 new genotypes: as of April 2011, new genotypes for VP7 (G20-G27), VP4 (P[28]-P[35]), VP6 (I12-I16), VP1 (R5-R9), VP2 (C6-C9), VP3 (M7-M8), NSP1 (A15-A16), NSP2 (N6-N9), NSP3 (T8-T12), NSP4 (E12-E14) and NSP5/6 (H7-H11) have been defined for RV strains recovered from humans, cows, pigs, horses, mice, South American camelids (guanaco), chickens, turkeys, pheasants, bats and a sugar glider. With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification/G- and P-type. In collaboration with the National Center for Biotechnology Information (NCBI), the RCWG is also working on developing a RV-specific resource for the deposition of nucleotide sequences. This resource will provide useful information regarding RV strains, including, but not limited to, the individual gene genotypes and epidemiological and clinical information. Together, the proposed nomenclature system and the NCBI RV resource will offer highly useful tools for investigators to search for, retrieve, and analyze the ever-growing volume of RV genomic data.

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Archives of Virology

Tập 156

1397-1413

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