Inhibition of TDP43-Mediated SNHG12-miR-195-SOX5 Feedback Loop Impeded Malignant Biological Behaviors of Glioma Cells

Molecular Therapy - Nucleic Acids - Tập 10 - Trang 142-158 - 2018
Xiaobai Liu1,2,3, Jian Zheng1,2,3, Yixue Xue4,5,6, Chengbin Qu1,2,3, Jiajia Chen4,5,6, Zhenhua Wang7, Zhen Li1,2,3, Lei Zhang1,2,3, Yunhui Liu1,2,3
1Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, China
2Liaoning Clinical Medical Research Center in Nervous System Disease, Shenyang 110004, China
3Key Laboratory of Neuro-oncology in Liaoning Province, Shenyang 110004, China
4Department of Neurobiology, College of Basic Medicine, China Medical University, Shenyang 110122, China
5Key Laboratory of Cell Biology, Ministry of Public Health of China, China Medical University, Shenyang 110122, China
6Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang 110122, China
7Department of Physiology, College of Basic Medicine, China Medical University, Shenyang, Liaoning 110122, China

Tài liệu tham khảo

Yuan, 2004, Isolation of cancer stem cells from adult glioblastoma multiforme, Oncogene, 23, 9392, 10.1038/sj.onc.1208311 Silber, 2008, miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells, BMC Med., 6, 14, 10.1186/1741-7015-6-14 Eramo, 2006, Chemotherapy resistance of glioblastoma stem cells, Cell Death Differ., 13, 1238, 10.1038/sj.cdd.4401872 Prensner, 2011, The emergence of lncRNAs in cancer biology, Cancer Discov., 1, 391, 10.1158/2159-8290.CD-11-0209 Zhao, 2016, Long non-coding RNA SNHG5 suppresses gastric cancer progression by trapping MTA2 in the cytosol, Oncogene, 35, 5770, 10.1038/onc.2016.110 Zhang, 2016, Long noncoding RNA SNHG1 predicts a poor prognosis and promotes hepatocellular carcinoma tumorigenesis, Biomed. Pharmacother., 80, 73, 10.1016/j.biopha.2016.02.036 Chen, 2016, Upregulated expression of long noncoding RNA SNHG15 promotes cell proliferation and invasion through regulates MMP2/MMP9 in patients with GC, Tumour Biol., 37, 6801, 10.1007/s13277-015-4404-0 Ruan, 2016, Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes cell proliferation and migration by upregulating angiomotin gene expression in human osteosarcoma cells, Tumour Biol., 37, 4065, 10.1007/s13277-015-4256-7 Coppin, 2017, Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells, Sci. Rep., 7, 43927, 10.1038/srep43927 Badawi, 2017, Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2, Cancer Lett., 393, 103, 10.1016/j.canlet.2017.02.010 Sun, 2014, Acceleration of TDP43 and FUS/TLS protein expressions in the preconditioned hippocampus following repeated transient ischemia, J. Neurosci. Res., 92, 54, 10.1002/jnr.23301 Kim, 2016, High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients, Cancer Lett., 374, 315, 10.1016/j.canlet.2016.02.021 Lytle, 2007, Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR, Proc. Natl. Acad. Sci. USA, 104, 9667, 10.1073/pnas.0703820104 Salmena, 2011, A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?, Cell, 146, 353, 10.1016/j.cell.2011.07.014 Wang, 2016, miR-195 inhibits tumor growth and angiogenesis through modulating IRS1 in breast cancer, Biomed. Pharmacother., 80, 95, 10.1016/j.biopha.2016.03.007 Wang, 2016, MicroRNA-195 inhibits proliferation of cervical cancer cells by targeting cyclin D1a, Tumour Biol., 37, 4711, 10.1007/s13277-015-4292-3 Hui, 2013, MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1, PLoS ONE, 8, e54932, 10.1371/journal.pone.0054932 Zhang, 2012, MicroRNA-195 plays a tumor-suppressor role in human glioblastoma cells by targeting signaling pathways involved in cellular proliferation and invasion, Neuro-oncol., 14, 278, 10.1093/neuonc/nor216 Fu, 2017, The Sox transcriptional factors: functions during intestinal development in vertebrates, Semin. Cell Dev. Biol., 63, 58, 10.1016/j.semcdb.2016.08.022 Lai, 2008, SOX5 controls the sequential generation of distinct corticofugal neuron subtypes, Neuron, 57, 232, 10.1016/j.neuron.2007.12.023 Baroti, 2016, Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain, Glia, 64, 122, 10.1002/glia.22919 Lefebvre, 2010, The SoxD transcription factors—Sox5, Sox6, and Sox13—are key cell fate modulators, Int. J. Biochem. Cell Biol., 42, 429, 10.1016/j.biocel.2009.07.016 Zhang, 2016, PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma, Carcinogenesis, 37, 320, 10.1093/carcin/bgw010 Tchougounova, 2009, Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence, Oncogene, 28, 1537, 10.1038/onc.2009.9 Ueda, 2007, Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients, Int. J. Cancer, 120, 1704, 10.1002/ijc.22472 Kamitani, 2002, Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced, Neuro-oncol., 4, 95, 10.1093/neuonc/4.2.95 Gdynia, 2007, Basal caspase activity promotes migration and invasiveness in glioblastoma cells, Mol. Cancer Res., 5, 1232, 10.1158/1541-7786.MCR-07-0343 Wang, 2017, High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin, Oncotarget, 8, 36185, 10.18632/oncotarget.15873 Kim, 2016, LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR, Nucleic Acids Res., 44, 2378, 10.1093/nar/gkw017 Guo, 2015, Regulation of MALAT1 expression by TDP43 controls the migration and invasion of non-small cell lung cancer cells in vitro, Biochem. Biophys. Res. Commun., 465, 293, 10.1016/j.bbrc.2015.08.027 Cai, 2017, Long non-coding RNA taurine upregulated 1 enhances tumor-induced angiogenesis through inhibiting microRNA-299 in human glioblastoma, Oncogene, 36, 318, 10.1038/onc.2016.212 Zhao, 2015, Gas5 exerts tumor-suppressive functions in human glioma cells by targeting miR-222, Mol. Ther., 23, 1899, 10.1038/mt.2015.170 Zhang, 2016, Altered long non-coding RNA transcriptomic profiles in brain microvascular endothelium after cerebral ischemia, Exp. Neurol., 277, 162, 10.1016/j.expneurol.2015.12.014 Duan, 2016, TGF-β1 regulating miR-205/miR-195 expression affects the TGF-β signal pathway by respectively targeting SMAD2/SMAD7, Oncol. Rep., 36, 1837, 10.3892/or.2016.5023 Yilaz Susluer, 2015, Downregulation of miR-195 via cyclosporin A in human glioblastoma cells, J. BUON, 20, 1337 Guo, 2015, MicroRNA-195 suppresses tumor cell proliferation and metastasis by directly targeting BCOX1 in prostate carcinoma, J. Exp. Clin. Cancer Res., 34, 91, 10.1186/s13046-015-0209-7 Liu, 2015, MiR-195 suppresses non-small cell lung cancer by targeting CHEK1, Oncotarget, 6, 9445, 10.18632/oncotarget.3255 Ujifuku, 2010, miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells, Cancer Lett., 296, 241, 10.1016/j.canlet.2010.04.013 Tuo, 2015, Long noncoding RNA UCA1 modulates breast cancer cell growth and apoptosis through decreasing tumor suppressive miR-143, Eur. Rev. Med. Pharmacol. Sci., 19, 3403 Zhang, 2013, Negative regulation of lncRNA GAS5 by miR-21, Cell Death Differ., 20, 1558, 10.1038/cdd.2013.110 Sun, 2016, Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway, Oncotarget, 7, 51784, 10.18632/oncotarget.10108 Ma, 2016, Long non-coding RNA ATB promotes glioma malignancy by negatively regulating miR-200a, J. Exp. Clin. Cancer Res., 35, 90, 10.1186/s13046-016-0367-2 Wang, 2016, The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873, Cell Death Differ., 23, 1394, 10.1038/cdd.2016.28 Hu, 2016, miRNA-205 targets VEGFA and FGF2 and regulates resistance to chemotherapeutics in breast cancer, Cell Death Dis., 7, e2291, 10.1038/cddis.2016.194 Lu, 2017, MiR-26a inhibits stem cell-like phenotype and tumor growth of osteosarcoma by targeting Jagged1, Oncogene, 36, 231, 10.1038/onc.2016.194 Al Zeyadi, 2015, Whole genome microarray analysis in non-small cell lung cancer, Biotechnol. Biotechnol. Equip., 29, 111, 10.1080/13102818.2014.989179 Wang, 2015, SOX5 promotes epithelial-mesenchymal transition and cell invasion via regulation of Twist1 in hepatocellular carcinoma, Med. Oncol., 32, 461 Mata-Rocha, 2014, The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression, FEBS Lett., 588, 3352, 10.1016/j.febslet.2014.07.024 Zhao, 2017, Gelsolin promotes radioresistance in non-small cell lung cancer cells through activation of phosphoinositide 3-kinase/Akt signaling, Technol. Cancer Res. Treat., 16, 512, 10.1177/1533034616643884 Huang, 2016, Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma, Oncotarget, 7, 25391, 10.18632/oncotarget.8603 Tomas, 2006, Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway, J. Cell Sci., 119, 2156, 10.1242/jcs.02942 Teng, 2016, Role of HCP5-miR-139-RUNX1 feedback loop in regulating malignant behavior of glioma cells, Mol. Ther., 24, 1806, 10.1038/mt.2016.103 Matouk, 2014, Oncofetal H19 RNA promotes tumor metastasis, Biochim. Biophys. Acta, 1843, 1414, 10.1016/j.bbamcr.2014.03.023 Zheng, 2016, CRNDE promotes malignant progression of glioma by attenuating miR-384/PIWIL4/STAT3 axis, Mol. Ther., 24, 1199, 10.1038/mt.2016.71 Zheng, 2017, TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway, J. Hematol. Oncol., 10, 52, 10.1186/s13045-017-0422-2 Cui, 2016, A tumor-suppressive microRNA, miR-504, inhibits cell proliferation and promotes apoptosis by targeting FOXP1 in human glioma, Cancer Lett., 374, 1, 10.1016/j.canlet.2016.01.051 Jeong, 2016, Long noncoding RNA linc00598 regulates CCND2 transcription and modulates the G1 checkpoint, Sci. Rep., 6, 32172, 10.1038/srep32172 Zhen, 2016, Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis, Tumour Biol., 37, 673, 10.1007/s13277-015-3843-y Huang, 2017, Long noncoding RNA LINC00673 is activated by SP1 and exerts oncogenic properties by interacting with LSD1 and EZH2 in gastric cancer, Mol. Ther., 25, 1014, 10.1016/j.ymthe.2017.01.017 Ma, 2014, MiR-181a regulates blood-tumor barrier permeability by targeting Krüppel-like factor 6, J. Cereb. Blood Flow Metab., 34, 1826, 10.1038/jcbfm.2014.152