Olfactory loss and nigrostriatal dopaminergic denervation in the elderly

Aarsland, 2003, Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study, Arch. Neurol., 60, 387, 10.1001/archneur.60.3.387 Adler, 2010, Incidental Lewy body disease: clinical comparison to a control cohort, Mov. Disord., 25, 642, 10.1002/mds.22971 Ashburner, 2003, Rigid Body Registration, 1 Beach, 2008, Reduced striatal tyrosine hydroxylase in incidental Lewy body disease, Acta Neuropathol., 115, 445, 10.1007/s00401-007-0313-7 Berendse, 2009, Diagnosing premotor Parkinson's disease using a two-step approach combining olfactory testing and DAT SPECT imaging, Parkinsonism Relat. Disord., 15, S26, 10.1016/S1353-8020(09)70774-6 Bohnen, 2006, Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease, J. Cereb. Blood Flow Metab., 26, 1198, 10.1038/sj.jcbfm.9600276 Bohnen, 2007, Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease, J. Neurol., 254, 84, 10.1007/s00415-006-0284-y Bohnen, 2003, Cortical cholinergic function is more severely affected in parkinsonian dementia than in Alzheimer disease: an in vivo positron emission tomographic study, Arch. Neurol., 60, 1745, 10.1001/archneur.60.12.1745 Bohnen, 2009, Age-associated striatal dopaminergic denervation and falls in community-dwelling subjects, J. Rehabil. Res. Dev., 46, 1045, 10.1682/JRRD.2009.03.0030 Bohnen, 2010, Olfactory dysfunction, central cholinergic integrity and cognitive impairment in Parkinson disease, Brain, 133, 1747, 10.1093/brain/awq079 Bosboom, 2009, Cholinergic modulation of MEG resting-state oscillatory activity in Parkinson's disease related dementia, Clin. Neurophysiol., 120, 910, 10.1016/j.clinph.2009.03.004 Chen, 2008, VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease, J. Neurochem., 105, 78, 10.1111/j.1471-4159.2007.05108.x Davies, 1976, Selective loss of central cholinergic neurons in Alzheimer's disease, Lancet, II, 1403, 10.1016/S0140-6736(76)91936-X Doty, 2007, Olfaction in Parkinson's disease, Parkinsonism Relat. Disord., 13, S225, 10.1016/S1353-8020(08)70006-3 Doty, 2009, The olfactory system and its disorders, Semin. Neurol., 29, 74, 10.1055/s-0028-1124025 Folstein, 1975, Mini-mental state: a practical method for grading the cognitive state of patients for the clinician, J. Psychiatry Res., 12, 189, 10.1016/0022-3956(75)90026-6 Klein, 2010, Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo, Neurol., 74, 885, 10.1212/WNL.0b013e3181d55f61 Kovacs, 2004, Mechanisms of olfactory dysfunction in aging and neurodegenerative disorders, Ageing Res. Rev., 3, 215, 10.1016/j.arr.2003.10.003 Lafreniere, 2009, Anosmia: loss of smell in the elderly, Otolaryngol. Clin. North Am., 42, 123, 10.1016/j.otc.2008.09.001 Larsson, 2009, Age-related loss of olfactory sensitivity: association to dopamine transporter binding in putamen, Neuroscience, 161, 422, 10.1016/j.neuroscience.2009.03.074 Maes, 1997, Multimodality image registration by maximization of mutual information, IEEE Trans. Med. Imaging, 16, 187, 10.1109/42.563664 Murphy, 1990, Olfactory thresholds are associated with degree of dementia in Alzheimer's disease, Neurobiol. Aging, 11, 465, 10.1016/0197-4580(90)90014-Q Nagren, 1995, Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]beta-CIT and [11C]beta-CFT, Nucl. Med. Biol., 22, 965, 10.1016/0969-8051(95)02018-7 Nagren, 1995, Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate, Nucl. Med. Biol., 22, 235, 10.1016/0969-8051(94)00083-V Perry, 1985, Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease, J. Neurol. Neurosurg. Psychiatry, 48, 413, 10.1136/jnnp.48.5.413 Ruberg, 1986, Acetylcholinesterase and butyrylcholinesterase in frontal cortex and cerebrospinal fluid of demented and non-demented patients with Parkinson's disease, Brain Res., 362, 83, 10.1016/0006-8993(86)91401-0 Seiberling, 2004, Aging and olfactory and taste function, Otolaryngol. Clin. North Am., 37, 1209, 10.1016/j.otc.2004.06.006 Serby, 1991, The nature and course of olfactory deficits in Alzheimer's disease, Am. J. Psychiatry, 148, 357, 10.1176/ajp.148.3.357 Siderowf, 2005, [99mTc]TRODAT-1 SPECT imaging correlates with odor identification in early Parkinson disease, Neurology, 64, 1716, 10.1212/01.WNL.0000161874.52302.5D Volkow, 1996, Dopamine transporters decrease with age in healthy subjects, J. Nucl. Med., 37, 554 Weinhard, 1998, Applications of 3D PET, 133 Wilson, 2009, Olfactory impairment in presymptomatic Alzheimer's disease, Ann. NY Acad. Sci., 1170, 730, 10.1111/j.1749-6632.2009.04013.x