Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

Agranoff, 1966, Chemical studies on memory fixation in goldfish, Brain Res., 1, 303, 10.1016/0006-8993(66)90095-3 Alberini, 1994, C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia, Cell, 76, 1099, 10.1016/0092-8674(94)90386-7 1994 Backsai, 1993, Spatially resolved dynamics of cAMP and protein kinase A subunits in Aplysia sensory neurons, Science, 260, 222, 10.1126/science.7682336 Baddeley, 1976 Barondes, 1968, Effects of acetoxycycloheximide on learning and memory of a light-dark discrimination, Nature, 218, 271, 10.1038/218271a0 Bourtchuladze, 1994, Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein, Cell, 79, 10.1016/0092-8674(94)90400-6 Boynton, 1992, Iatheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis, Genetics, 131, 655, 10.1093/genetics/131.3.655 Byers, 1981, Defect in cyclic AMP phosphodiesterase due to the dunce mutation of learning in Drosophila melanogaster, Nature, 289, 79, 10.1038/289079a0 Byrne, 1993, Roles of second messenger pathways in neuronal plasticity and in learning and memory, 47 Chen, 1986, Molecular analysis of cDNA clones and the corresponding genomic coding sequences of the Drosophila dunce gene, the structural gene for cAMP-dependent phosphodiesterase, 83, 9313 Dash, 1990, Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation, Nature, 345, 718, 10.1038/345718a0 Davis, 1984, Protein synthesis and memory: a review, Psychol. Bull., 96, 518, 10.1037/0033-2909.96.3.518 de Groot, 1993, Hormonal control of gene expression: multiplicity and versatility of cyclic adenosine 3′,5′-monophosphate-responsive nuclear regulators, Mol. Endocrinol., 7, 145 Drain, 1991, cAMP-dependent protein kinase and the disruption of learning in transgenic flies, Neuron, 6, 71, 10.1016/0896-6273(91)90123-H Dudai, 1976, Dunce, a mutant of Drosophila deficient in learning, 73, 1684 Dura, 1993, Identification of linotte, a new gene affecting learning and memory in Drosophila melanogaster, J. Neurogenet., 9, 1, 10.3109/01677069309167272 Dwarki, 1990, Both the basic region and the “leucine zipper” domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation, EMBO J., 9, 225, 10.1002/j.1460-2075.1990.tb08099.x Ebbinghaus, 1885 Folkers, 1993, radish, a Drosophila mutant deficient in consolidated memory, 90, 8123 Foulkes, 1992, More is better: activators and repressors from the same gene, Cell, 68, 411, 10.1016/0092-8674(92)90178-F Foulkes, 1991, CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription, Cell, 64, 739, 10.1016/0092-8674(91)90503-Q Foulkes, 1992, Developmental switch of CREM function during spermatogenesis: from antagonist to transcriptional activator, Nature, 355, 80, 10.1038/355080a0 Frey, 1993, Effects of cAMP stimulate a late stage of LTP in hippocampal CA1 neurons, Science, 260, 1661, 10.1126/science.8389057 Gonzalez, 1989, Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133, Cell, 59, 675, 10.1016/0092-8674(89)90013-5 Habener, 1990, Cyclic AMP response element binding proteins: a cornucopia of transcription factors, Mol. Endocrinol., 4, 1087, 10.1210/mend-4-8-1087 Hai, 1991, Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity, 88, 3720 Hai, 1989, Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA binding heterodimers, Genes Dev., 3, 2083, 10.1101/gad.3.12b.2083 Hovemann, 1988, Two genes encode related cytoplasmic elongation factors 1 alpha (EF-1 α) in Drosophila melanogaster with continuous and stage specific expression, Nucl. Acids Res., 16, 3175, 10.1093/nar/16.8.3175 Huang, 1994, Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization, Learning and Memory, 1, 74, 10.1101/lm.1.1.74 Kaang, 1993, Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons, Neuron, 10, 427, 10.1016/0896-6273(93)90331-K Kandel, 1982, Molecular biology of an elementary form of learning: modulation of transmitter release by cAMP, Science, 218, 433, 10.1126/science.6289442 Kandel, 1987, Synaptic modulation and learning: new insights into synaptic transmission from the study of behavior, 471 Landschulz, 1988, The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins, Science, 240, 1759, 10.1126/science.3289117 Levin, 1992, The Drosophila learning and memory gene rutabaga encodes a Ca2+/calmodulin-responsive adenylyl cyclase, Cell, 68, 479, 10.1016/0092-8674(92)90185-F Livingstone, 1984, Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant, Cell, 37, 205, 10.1016/0092-8674(84)90316-7 Montarolo, 1986, A critical period for macromolecular synthesis in long-term heterosynaptic facilitation in Aplysia, Science, 234, 1249, 10.1126/science.3775383 Parker, 1985, Characterization of the myosin light-chain-2 gene of Drosophila melanogaster, Mol. Cell. Biol., 5, 3058 Quinn, 1974, Conditioned behavior in Drosophila melanogaster, 71, 708 Rosenzweig, 1984, Basic processes and modulatory influences in the stages of memory formation, 263 Rubin, 1982, Genetic transformation of Drosophila with transposable element vectors, Science, 218, 348, 10.1126/science.6289436 Schacher, 1988, cAMP evokes long-term facilitation in Aplysia sensory neurons that requires new protein synthesis, Science, 240, 1667, 10.1126/science.2454509 Skoulakis, 1993, Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory, Neuron, 11, 197, 10.1016/0896-6273(93)90178-T Sokal, 1981 Spradling, 1982, Transposition of cloned P elements into Drosophila germ line chromosomes, Science, 218, 341, 10.1126/science.6289435 Tully, 1993, Differential effects of dunce mutations on associative learning and memory in Drosophila, J. Neurogenet., 9, 55, 10.3109/01677069309167275 Tully, 1985, Classical conditioning and retention in normal and mutant Drosophila melanogaster, J. Comp. Physiol., 157, 263, 10.1007/BF01350033 Tully, 1994, Genetic dissection of consolidated memory in Drosophila, Cell, 79, 10.1016/0092-8674(94)90398-0 Yamamoto, 1988, Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB, Nature, 334, 494, 10.1038/334494a0