Indium-111 autologous leucocyte scanning: comparison with radiology for imaging the colon in inflammatory bowel disease.

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Balfour HH. Rubella reimmunisation now. Am J Dis Child 1979;133: 1231-3.

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Zealley H, Edmond E. Rubella screening and immunisation of schoolgirls: results six to seven years after vaccination. Br MedJ3 1982;284:382-4.

Hillary IB, Griffith AH. Persistence of antibody 10 years after vaccination with Wistar RA27/3 strain live attenuated rubella vaccine. Br Med J 1980;280:1580-1.

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(Accepted 8 June 1982)

RRITISH MEDICAL JOURNAL VOLUME 285 24 JULY 1982 the initial site of localisation. Steroids and sulphasalazine did not prevent localisation.

BRITISH MEDICAL JOURNAL VOLUME 285 24 JULY 1982 labelled in saline, which we now think give poorer images than cells labelled in plasma.'6 Colonoscopy was available in one of these cases and agreed with the scan result. Nevertheless, between the scan and endoscopy the patient was given high-dose steroid treatment, which may have altered the extent of colitis. In the other discrepancy between scan and radiology colonoscopy confirmed the scan estimate. A major theoretical objection to "'In-leucocyte scans for assessing inflammatory bowel disease is

Kadir S, Strauss W. Evaluation of inflammatory bowel disease with 99m-Tc DTPA. Radiology 1979;130:443-6.

Van Aardenne YT, Winter WA, Veredgaal WP, Talonis WK. Detection of inflammatory bowel disease with 99m-Tc DTPA. Diagn Imaging 1980; 49:334-8.

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Carrol B, Silverman PM, Goodwin DA, McDougall IR. Ultrasonography and indium-lll white blood cell scanning for the detection of intraabdominal abscesses. Radiology 1981;140:155-60.

Segal AW, Ensell J, Munro JD, Sarner M. Indium-lll tagged leucocytes in the diagnosis of inflammatory bowel disease. Lancet 1981;ii:230-2.

Sinn H, Sylvester DJ. Simplified cell labelling with indium-lll acetylacetone. BrJ' Radiol 1979;52:758-9.

Danpure HJ, Osman S, Brady F. The labelling of blood cells in plasma with 1 1 -tropolonate. Br J Radiol 1982;55:247-9.

Whorwell PJ, Isaacson PJ. Toxic dilatation of colon in Crohn's disease. Lancet 1981;ii:1334-7.

Caffee JH, Watts G, Mena I. 67Gallium citrate scanning in the diagnosis of intraabdominal abscess. Am J Surg 1977;133:665-9.

Peters AM, Saverymuttu SH, Danpure HJ, Osman S, Lavender JP, Chadwick VS. Granulocyte kinetics: isolation and labelling in plasma abolishes lung sequestration. Clin Sci 1982;62:6P-7P. 17 Rhodes JM, Bartholomew TC, Jewell DP. Inhibition of leucocyte motility by drugs in ulcerative colitis. Gut 1981;22:648-53.

(Accepted 4 June 1982)