Ständer, 2017, Dynamic Pruritus Score: Evaluation of the validity and reliability of a new instrument to assess the course of pruritus, Acta Derm Venereol., 97, 230, 10.2340/00015555-2494
Weisshaar, 2019, European S2K guideline in chronic pruritus, Acta Dermatol Venereol, 99, 469, 10.2340/00015555-3164
Makar, 2021, Chronic kidney disease-associated pruritus: A review, Kidney Blood Pres Res, 7, 1
Agarwal, 2021, Chronic kidney disease-associated pruritus, Toxins, 28, 527, 10.3390/toxins13080527
Narita, 2006, Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients, Kidney Int, 69, 1626, 10.1038/sj.ki.5000251
Pisoni, 2006, Pruritus in haemodialysis patients: International results from the Dialysis Outcomes and Practice Patterns Study (DOPPS), Nephrol Dial Transplant, 21, 3495, 10.1093/ndt/gfl461
Ramakrishnan, 2013, Clinical characteristics and outcomes of end-stage renal disease patients with self-reported pruritus symptoms, Int J Nephrol Renovasc Dis., 7, 1
Rayner, 2017, International Comparisons of Prevalence, awareness, and treatment of pruritus in people on hemodialysis, Clin J Am Soc Nephrol., 12, 2000, 10.2215/CJN.03280317
Simonsen, 2017, Treatment of uremic pruritus: A systematic review, Am J Kidney Dis., 70, 638, 10.1053/j.ajkd.2017.05.018
Hercz, 2020, Interventions for itch in people with advance chronic kidney disease, Cochrane Database Syst Rev.
Mettang, 1990, Uremic pruritus in patients on hemodialysis or continuous ambulatory peritoneal dialysis (CAPD). The role of plasma histamine and skin mast cells, Clinical Nephrology, 34, 136
Kato, 2001, Polymethylmethacrylate efficacy in reduction of renal itching in hemodialysis patients: Crossover study and role of tumor necrosis factor-alpha, Artif Organs, 25, 441, 10.1046/j.1525-1594.2001.025006441.x
Massry, 1968, Intractable pruritus as a manifestation of secondary hyperparathyroidism in uremia. Disappearance of itching after subtotal parathyroidectomy, N Engl J Med, 279, 697, 10.1056/NEJM196809262791308
Peer G. Kivity S. Agami O. Fireman E. Silverberg D. Blum M.et al. Randomised crossover trial of naltrexone in uraemic pruritus. Lancet. 348. 199. 1552-1554
Ting, 2020, Uremic pruritus and long-term morbidities in the dialysis population, PLoS One, 15, e0241088, 10.1371/journal.pone.0241088
Weng, 2018, Uremic pruritus is associated with two-year cardiovascular mortality in long term hemodialysis patients, Kidney Blood Press Res, 43, 1000, 10.1159/000490689
Verduzco, 2020, CKD-associated pruritus: New insights into diagnosis, pathogenesis, and management, Kidney Int Rep., 5, 1387, 10.1016/j.ekir.2020.04.027
Patel, 2007, An update on pruritus associated with CKD, Am J Kidney Dis, 50, 11, 10.1053/j.ajkd.2007.03.010
Shirazian, 2017, Chronic kidney disease-associated pruritus: Impact on quality of life and current management challenges, Int J Nephrol Renov Dis., 10, 11, 10.2147/IJNRD.S108045
Manenti, 2021, Do you feel itchy? A guide towards diagnosis and measurement of chronic kidney disease-associated pruritus in dialysis patients,, Clin Kidney J, 14, i8, 10.1093/ckj/sfab143
Mathur, 2010, A longitudinal study of uremic pruritus in hemodialysis patients, Clin J Am Soc Nephrol, 5, 1410, 10.2215/CJN.00100110
Min, 2016, Comparison of uremic pruritus between patients undergoing hemodialysis and peritoneal dialysis, Kidney Res Clin Pract, 35, 107, 10.1016/j.krcp.2016.02.002
Reich, 2012, Visual analogue scale: Evaluation of the instrument for the assessment of pruritus, Acta Derm Venereol, 92, 497, 10.2340/00015555-1265
Kimmel, 2006, The role of micro-inflammation in the pathogenesis of uraemic pruritus in haemodialysis patients, Nephrol Dial Transplant., 21, 749, 10.1093/ndt/gfi204
Virga, 2002, Inflammation and pruritus in haemodialysis patients, Nephrol Dial Transplant., 17, 2164, 10.1093/ndt/17.12.2164
Forouhari, 2022, Pruritus-reducing effects of omega-3 fatty acids in hemodialysis patients: A cross-over randomized clinical trial, Hemodial Int, 3
Wieczorek, 2020, Opioid receptors expression in the skin of haemodialysis patients suffering from uraemic pruritus, J Eur Acad Dermatology Venereol, 34, 2368, 10.1111/jdv.16360
Mathur, 2016, Improvement of quality of life in hemodialysis patients with uremic pruritus as measured by the skindex-10 questionnaire: Effect of a novel kappa opiod receptor agonist, CR845 [abstract no: TH-PO1040], J Am Soc Nephrol, 27, 338A
Castello, 2011, Efficacy of topical hydrating and emollient lotion containing 10% urea ISDIN® plus dexpanthenol (Ureadin Rx 10) in the treatment of skin xerosis and pruritus in hemodialyzed patients: An open prospective pilot trial, G Ital Dermatol Venereol., 146, 321
Okada, 2004, Effect of skin care with an emollient containing a high water content on mild uremic pruritus, Ther Apher Dial., 8, 419, 10.1111/j.1526-0968.2004.00175.x
Gooding, 2010, Systematic review of topical capsaicin in the treatment of pruritus, Int J Dermatol., 49, 858, 10.1111/j.1365-4632.2010.04537.x
Young, 2009, A pramoxine-based anti-itch lotion is more effective than a control lotion for the treatment of uremic pruritus in adult hemodialysis patients, J Dermatol Treat, 20, 76, 10.1080/09546630802441218
Cupisti, 2020, Charcoal for the management of pruritus and uremic toxins in patients with chronic kidney disease, Curr Opin Nephrol Hypertens., 29, 71, 10.1097/MNH.0000000000000567
Aucella, 2007, Uraemic itching: Do polymethylmethacrylate dialysis membranes play a role?, Nephrol Dial Transplant., 22, v8, 10.1093/ndt/gfm293
Kato, 2001, Polymethylmethacrylate efficacy in reduction of renal itching in hemodialysis patients: Crossover study and role of tumor necrosis factor-alpha, Artif Organs., 25, 441, 10.1046/j.1525-1594.2001.025006441.x
Lau, 2016, Gabapentin for uremic pruritus in hemodialysis patients: A qualitative systematic review, Can J Kidney Health Dis., 3, 14, 10.1186/s40697-016-0107-8
Rayner, 2012, Uraemic pruritus: Relief of itching by gabapentin and pregabalin, Nephron, 122, 75
Ada, 2005, Treatment of uremic pruritus with narrowband ultraviolet B phototherapy: An open pilot study, J Am Acad Dermatol., 53, 149, 10.1016/j.jaad.2004.12.052
Blachley, 1985, Uremic pruritus: skin divalent ion content and response to ultraviolet phototherapy, Am J Kidney Dis., 5, 237, 10.1016/S0272-6386(85)80115-3
Gholyaf, 2020, Effect of mirtazapine on pruritus in patients on hemodialysis: A cross-over pilot study, Int Urol Nephrol [Internet]., 52, 1155, 10.1007/s11255-020-02473-3
Shakiba, 2012, Effect of sertraline on uremic pruritus improvement in ESRD patients, Int J Nephrol [Internet]., 12, 1
Pauli-Magnus, 2000, Naltrexone.does not relieve uremic pruritus: Results of a randomized, double-blind, placebo controlled crossover study, J Am Soc Nephrol., 11, 514, 10.1681/ASN.V113514
Albert-Vartanian, 2016, Will peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?, J Clin Pharmacol Ther, 371, 10.1111/jcpt.12404
Fishbane, 2020, A phase 3 trial of difelikefalin in hemodialysis patients with pruritus, N Engl J Med., 382, 222, 10.1056/NEJMoa1912770
Wikstrom, 2005, Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies, J Am Soc Nephrol., 16, 3742, 10.1681/ASN.2005020152
Kumagai, 2010, Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on se-vere itch in 337 haemodialysis patients: A phase III, randomized, double-blind, placebo-controlled study, Nephrol Dial Transplant., 25, 1251, 10.1093/ndt/gfp588
Retirada de la solicitud de autorización de comercialización de Winfuran (nalfurafina). 24 de enero de 2014 EMA/33514/2014.
Mathur, 2017, A multicenter, randomized, double-blind, placebo-controlled trial of nalbuphine ER tablets for uremic pruritus, Am J Nephrol, 46, 450, 10.1159/000484573
Martin, 2020, Have we just scratched the surface? A narrative review of uremic pruritus in 2020, Can J Kidney Health Dis., 7, 10.1177/2054358120954024
Kinugasa, 2021, Anti-pruritic effect of nemolizumab in hemodialysis patients with uremic pruritus: a phase II, randomized, double-blind, placebo-controlled clinical study, Clin Exp Nephrol., 25, 875, 10.1007/s10157-021-02047-2