In utero phthalate effects in the female rat: A model for MRKH syndrome

Bernardini, 2009, Recurrent microdeletion at 17q12 as a cause of Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome: two case reports, Orphanet Journal of Rare Diseases, 4, 25, 10.1186/1750-1172-4-25 Carruthers, 2005, Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate, Birth Defects Research B, 74, 277, 10.1002/bdrb.20050 Cheroki, 2006, Report of a del22q11 in a patient with Mayer–Rokitansky–Kuster–Hauser (MRKH) anomaly and exclusion of WNT-4, RAR-gamma, and RXR-alpha as major genes determining MRKH anomaly in a study of 25 affected women, American Journal of Medical Genetics, 140, 1339, 10.1002/ajmg.a.31254 Diemen, 2006, Experimental model to induce obesity in rats, Acta Cirurgica Brasileira, 21, 425, 10.1590/S0102-86502006000600013 Ema, 2000, Effects of dibutyl phthalate on reproductive function in pregnant and pseudopregnant rats, Reproductive Toxicology, 14, 13, 10.1016/S0890-6238(99)00066-0 Fisher, 2003, Human ‘testicular dysgenesis syndrome’: a possible model using in-utero exposure of the rat to dibutyl phthalate, Human Reproduction, 18, 1383, 10.1093/humrep/deg273 Gray, 2006, Chronic di-n-butyl phthalate exposure in rats reduces fertility and alters ovarian function during pregnancy in female Long Evans hooded rats, Toxicological Sciences, 93, 189, 10.1093/toxsci/kfl035 Gray, 1999, Toxicology and Industrial Health, 15, 94, 10.1191/074823399678846664 Gray, 1983, Postnatal developmental alterations following prenatal exposure to the herbicide 2,4-dichlorophenyl-p-nitrophenyl ether: a dose response evaluation in the mouse, Toxicology and Applied Pharmacology, 67, 1, 10.1016/0041-008X(83)90239-9 Hotchkiss, 2004, A mixture of the antiandrogens linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion, Biology of Reproduction, 71, 1852, 10.1095/biolreprod.104.031674 Howdeshell, 2008, A mixture of five phthalate esters inhibits fetal testicular testosterone production in the Sprague–Dawley rat in a cumulative, dose-additive manner, Toxicological Sciences, 105, 153, 10.1093/toxsci/kfn077 Howdeshell, K.H., Rider, C.V., Wilson, V.S., Furr, J., Lambright, C.R., Gray Jr., L.E. Dose additive inhibition of the expression of steroidogenic genes and induction of reproductive malformations of a phthalate mixture in the Male Sprague Dawley rat (in preparation). Mello, 2001, Glucose tolerance and insulin action in monosodium glutamate (MSG) obese exercise-trained rats, Physiology, Chemical, Physical & Medicine, 33, 63 Morcel, 2007, Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome, Orphanet Journal of Rare Diseases, 2, 13, 10.1186/1750-1172-2-13 Mylchreest, 1998, Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: an antiandrogenic mechanism?, Toxicological Sciences, 43, 47, 10.1093/toxsci/43.1.47 Mylchreest, 1999, Disruption of androgen-regulated male reproductive development by di(n-butyl) phthalate during late gestation in rats is different from flutamide, Toxicology and Applied Pharmacology, 156, 81, 10.1006/taap.1999.8643 Mylchreest, 2000, Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to di(n-butyl) phthalate during late gestation, Toxicological Sciences, 55, 143, 10.1093/toxsci/55.1.143 Narotsky, 1995, A multidisciplinary approach to toxicological screening: II. Developmental toxicity, Journal of Toxicology and Environmental Health, 45, 145, 10.1080/15287399509531987 Ostby, 1985, The postnatal effects of prenatal exposure to low doses of nitrofen (2,4-dichlorophenyl-p-nitrophenyl ether) in Sprague–Dawley rats, Toxicology, 34, 285, 10.1016/0300-483X(85)90139-8 Sharpe, 2004, How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?, British Medical Journal, 328, 447, 10.1136/bmj.328.7437.447 Sukhanov, 1999, Neonatal monosodium glutamate treatment alters rat intestinal muscle reactivity to some agonists, European Journal of Pharmacology, 386, 247, 10.1016/S0014-2999(99)00751-7 Sultan, 2009, Mayer–Rokitansky–Kuster–Hauser syndrome: recent clinical and genetic findings, Gynecological Endocrinology: The Official Journal of the International Society of Gynecological Endocrinology, 25, 8, 10.1080/09513590802288291 Takahashi, 2006, Insulin resistance and low sympathetic nerve activity in the Tsumura Suzuki obese diabetic mouse: a new model of spontaneous type 2 diabetes mellitus and obesity, Metabolism, 55, 1664, 10.1016/j.metabol.2006.08.007 Tomonari, 2006, Effect of di(2-ethylhexyl) phthalate (DEHP) on genital organs from juvenile common marmosets: I. Morphological and biochemical investigation in 65-week toxicity study, Journal of Toxicology and Environmental Health Part A, 69, 1651, 10.1080/15287390600630054 Wickman, 1993, Nitrofen-induced congenital diaphragmatic defects in CD1 mice, Teratology, 47, 119, 10.1002/tera.1420470204