α-Synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy

Neuroscience Letters - Tập 405 - Trang 223-225 - 2006
Clifford W. Shults1,2, Jennifer M. Barrett1, Deborah Fontaine1
1Department of Neurosciences, University of California–San Diego, La Jolla, CA, USA;
2Neurology Service, VA San Diego Healthcare System, San Diego, CA, USA

Tài liệu tham khảo

Beal, 2003, Bioenergetic approaches for neuroprotection in Parkinson's disease, Ann. Neurol., 53, S39, 10.1002/ana.10479 Benecke, 1993, Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes, Brain, 116, 1451, 10.1093/brain/116.6.1451 Cabin, 2002, Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein, J. Neurosci., 22, 8797, 10.1523/JNEUROSCI.22-20-08797.2002 Frucht, 2004, Clinical assessments, 37 Fujiwara, 2002, alpha-Synuclein is phosphorylated in synucleinopathy lesions, Nat. Cell. Biol., 4, 160, 10.1038/ncb748 Galvin, 2001, Synucleinopathies: clinical and pathological implications, Arch. Neurol., 58, 186, 10.1001/archneur.58.2.186 Gilman, 1999, Consensus statement on the diagnosis of multiple system atrophy, J. Neurol. Sci., 163, 94, 10.1016/S0022-510X(98)00304-9 Haas, 1995, Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease, Ann. Neurol., 37, 714, 10.1002/ana.410370604 Hughes, 2001, Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease, Neurology, 57, 1497, 10.1212/WNL.57.8.1497 Kutti, 1971, Platelet survival in man, Scand. J. Haemat., 8, 336, 10.1111/j.1600-0609.1971.tb00883.x Li, 2002, Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects, J. Alzheimers Dis., 4, 309, 10.3233/JAD-2002-4406 Michell, 2005, Skin and platelet alpha-synuclein as peripheral biomarkers of Parkinson's disease, Neurosci. Lett., 381, 294, 10.1016/j.neulet.2005.02.030 Park, 2002, Evidence that alpha-synuclein functions as a negative regulator of Ca(++)-dependent alpha-granule release from human platelets, Blood, 100, 2506, 10.1182/blood.V100.7.2506 Parker, 1989, Abnormalities of the electron transport chain in idiopathic Parkinson's disease, Ann. Neurol., 26, 719, 10.1002/ana.410260606 Rockenstein, 2002, Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters, J. Neurosci. Res., 68, 568, 10.1002/jnr.10231 Shults, 2006, Lewy bodies, Proc. Natl. Acad. Sci. U.S.A., 103, 1661, 10.1073/pnas.0509567103 Shults, 2005, Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy, J. Neurosci., 25, 10689, 10.1523/JNEUROSCI.3527-05.2005 Wenning, 2004, Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS), Mov. Disord., 19, 1391, 10.1002/mds.20255