Zebrafish cancer and metastasis models for in vivo drug discovery

Drug Discovery Today: Technologies - Tập 10 - Trang e83-e89 - 2013
Jennifer Tat1,2, Mingyao Liu2,3, Xiao-Yan Wen1,2
1Zebrafish Centre for Advanced Drug Discovery, Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario M5B 1T8, Canada
2Department of Physiology, Faculty of Medicine, University of Toronto, Canada
3Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada

Tài liệu tham khảo

Baker, 2010, Screening: the age of the fishes, Nat. Methods, 8, 47, 10.1038/nmeth0111-47 Zon, 2005, In vivo drug discovery in the zebrafish, Nat. Rev. Drug Discov., 4, 35, 10.1038/nrd1606 Langenau, 2003, Myc-induced T cell leukemia in transgenic zebrafish, Science, 299, 887, 10.1126/science.1080280 Liu, 2011, Zebrafish models for cancer, Annu. Rev. Pathol., 6, 71, 10.1146/annurev-pathol-011110-130330 Santoriello, 2010, Kita driven expression of oncogenic HRAS leads to early onset and high penetrant melanoma in zebrafish, PLoS One, 5, 12, 10.1371/journal.pone.0015170 Nguyen, 2011, An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening, Dis. Model. Mech., 5, 1 Amatruda, 2008, Genetic models of cancer in zebrafish, Int. Rev. Cell Mol. Biol., 27, 1, 10.1016/S1937-6448(08)01201-X Wang, 2010, Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer, Eur. Urol., 58, 418, 10.1016/j.eururo.2010.05.024 Berghmans, 2005, Making waves in cancer research: new models in the zebrafish, Biotechniques, 39, 227, 10.2144/05392RV02 Langheinrich, 2002, Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signalling, Curr. Biol., 12, 2023, 10.1016/S0960-9822(02)01319-2 Haramis, 2006, Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia, EMBO Rep., 7, 444, 10.1038/sj.embor.7400638 Faucherre, 2008, Zebrafish pten genes have overlapping and nonredundant functions in tumorigenesis and embryonic development, Oncogene, 27, 1079, 10.1038/sj.onc.1210730 Nicoli, 2007, Mammalian tumor xenografts induce neovascularisation in zebrafish embryos, Cancer Res., 67, 2927, 10.1158/0008-5472.CAN-06-4268 Marques, 2009, Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model, BMC Cancer, 9, 1, 10.1186/1471-2407-9-128 Lee, 2009, Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model, Proc. Natl. Acad. Sci. U.S.A., 106, 19485, 10.1073/pnas.0909228106 Stoletov, 2010, Visualizing extravasation dynamics of metastatic tumor cells, J. Cell Sci., 123, 2332, 10.1242/jcs.069443 Stoletov, 2008, Catch of the day: zebrafish as a human cancer model, Oncogene, 27, 4509, 10.1038/onc.2008.95 White, 2008, Transparent adult zebrafish as a tool for in vivo transplantation analysis, Cell Stem Cell, 7, 183, 10.1016/j.stem.2007.11.002 Smith, 2010, High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia, Blood, 115, 3296, 10.1182/blood-2009-10-246488 Taylor, 2009, Zebrafish tumor assays: the state of transplantation, Zebrafish, 6, 339, 10.1089/zeb.2009.0607 Jensen, 2011, Zebrafish models to study hypoxia-induced pathological angiogenesis in malignant and non-malignant diseases, Birth Defects Res., 93, 182, 10.1002/bdrc.20203 Cheng, 2011, Whole-animal imaging, gene function, and the Zebrafish Phenome Project, Curr. Opin. Genet. Dev., 21, 620, 10.1016/j.gde.2011.08.006 Yanik, 2011, Technologies for micromanipulating, imaging and phenotyping small invertebrates and vertebrates, Annu. Rev. Biomed. Eng., 13, 185, 10.1146/annurev-bioeng-071910-124703 Pardo-Martin, 2010, High-throughput in vivo vertebrate screening, Nat. Methods, 7, 634, 10.1038/nmeth.1481 Kabli, 2010, In vivo magnetic resonance imaging to detect malignant melanoma in adult zebrafish, Zebrafish, 7, 143, 10.1089/zeb.2009.0649 Goessling, 2007, Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors, Nat. Methods, 4, 551, 10.1038/nmeth1059 Zhang, 2011, Batch transfer of zebrafish embryos into multiwell plates, IEEE Trans. Autom. Sci. Eng., 8, 625, 10.1109/TASE.2011.2121903 Wang, 2007, A fully automated robotic system for microinjection of zebrafish embryos, PLoS One, 2, 1, 10.1371/journal.pone.0000862 Huang, 2011, A universal piezo-driven ultrasonic cell microinjection system, Biomed. Microdevices, 13, 743, 10.1007/s10544-011-9544-4 Petzold, 2010, SCORE imaging: specimen in a corrected optical rotational enclosure, Zebrafish, 7, 149, 10.1089/zeb.2010.0660 Gehrig, 2009, Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos, Nat. Methods, 6, 911, 10.1038/nmeth.1396 Sabaliaukas, 2006, High-throughput zebrafish histology, Methods, 39, 246, 10.1016/j.ymeth.2006.03.001 Vogt, 2009, Automated image-based phenotypic analysis in zebrafish embryos, Dev. Dyn., 238, 656, 10.1002/dvdy.21892 Ewan, 2010, A useful approach to identify novel small-molecule inhibitors of wnt-dependent transcription, Cancer Res., 70, 5963, 10.1158/0008-5472.CAN-10-1028 Hao, 2010, In vivo structure activity relationship study of dorsomorphin analogs identifies selective VEGF and BMP inhibitors, ACS Chem. Biol., 5, 245, 10.1021/cb9002865 Crawford, 2011, Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants, PLoS One, 6, e14694, 10.1371/journal.pone.0014694 Chong, 2007, New uses for old drugs, Nature, 448, 645, 10.1038/448645a Zhang, 2011, SKLB1002, a novel potent inhibitor of VEGF receptor 2 signalling, inhibits angiogenesis and tumor growth in vivo, Clin. Cancer Res., 17, 4439, 10.1158/1078-0432.CCR-10-3109 Cheng, 2011, Nanotherapeutics in angiogenesis: synthesis and in vivo assessment of drug efficacy and biocompatibility in zebrafish embryos, Int. J. Nanomed., 6, 2007, 10.2147/IJN.S20145 Gou, 2011, Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo, Nanoscale, 3, 1558, 10.1039/c0nr00758g Farokhzhad, 2009, Impact of nanotechnology on drug delivery, ACS Nano, 2, 16, 10.1021/nn900002m Snaar-Jagalska, 2009, ZF-CANCER: developing high-throughput bioassays for human cancers in zebrafish, Zebrafish, 6, 441, 10.1089/zeb.2009.0614