Occurrence and risk factors associated to Toxoplasma gondii infection in sheep from Rio de Janeiro, Brazil

Tropical Animal Health and Production - Tập 46 - Trang 1463-1466 - 2014
Rachel Ingrid Juliboni Cosendey-KezenLeite1, Francisco Carlos Rodrigues de Oliveira2, Edwards Frazão-Teixeira2, Jitender Prakash Dubey3, Guilherme Nunes de Souza4, Ana Maria Reis Ferreira5, Walter Lilenbaum1
1Laboratório de Bacteriologia Animal, Universidade Federal Fluminense, Niterói, Brazil
2Laboratório de Sanidade Animal, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Brazil
3Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, United States Department of Agriculture, Beltsville, USA
4Embrapa Gado de Leite, Juiz de Fora, Brazil
5Departamento de Patologia Clínica e Reprodução, Universidade Federal Fluminense, Niterói, Brazil

Tóm tắt

Toxoplasmosis is an important cause of abortion in sheep and a zoonotic risk to humans, leading to significant hazards to health and to economic losses. This study examined the seroprevalence and associated risk factors for infection with Toxoplasma gondii in 379 sheep from 12 flocks in Rio de Janeiro state, Brazil. Using the modified agglutination test (MAT), 202 (53.3 %) of 379 were seropositive with titers of 1:25 in 65, 1:50 in 40, 1:100 in 23, 1:200 in 11, 1:400 in 36, 1:800 in 7, 1:1,600 in 1, and 1:3,200 or higher in 19 sheep. The most significant factors associated with T. gondii seropositivity in sheep were age, gender, and veterinary care. Finding of T. gondii antibodies in 97 of the 202 sheep in titers of 1:100 or higher is indicative of persistently infected animals. This high level of seropositivity requires urgent control measures to reduce impact on animal productivity and public health.

Tài liệu tham khảo

Andrade, M.M.C., Carneiro, M., Medeiros, A.D., Neto, V.A., Vitor, R.W.A., 2013. Seroprevalence and risk factors associated with ovine toxoplasmosis in Northeast Brazil. Parasite, 20, 20. CDC, 2010. Centers for Disease Control and Prevention. https://wwwn.cdc.gov/epiinfo/html/downloads.htm Costa, D. G., Marvulo, M. F., Silva, J. S., Santana, S. C., Magalhães, F. J., Lima Filho, C. D., Ribeiro, V. O., Alves, L. C., Mota, R. A., Dubey, J. P, Silva, J. C., 2012. Seroprevalence of Toxoplasma gondii in domestic and wild animals from the Fernando De Noronha, Brazil. Journal of Parasitology, 98 (3), 679--680. Dubey, J.P., 2009. Toxoplasmosis in sheep – the last 20 years. Veterinary Parasitology, 163, 1–14. Dubey, J.P., 2010. Toxoplasmosis of Animals and Humans. Second Edition. Boca Raton, Florida: CRC Press, 1–313. Dubey, J.P. and Desmonts, G., 1987. Serological responses of equids fed Toxoplasma gondii oocysts. Equine Veterinary Journal, 19 (4), 337--343. Dubey, J.P., Lago, E.G., Gennari, S.M., Su, C., Jones, J.L., 2012. Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology. Parasitology, 139 (11), 1375--1424. FAO, 2010. Food and Agriculture Organization of the United Nations: FAOSTAT Database. http://faostat.fao.org. Halos, L., Thébault, A., Aubert, D., Thomas, M., Perret, C., Geers, R., Alliot, A., Escotte-Binet, S., Ajzenberg, D., Dardé, M.L., Durand, B., Boireau, P., Villena, I., 2010. An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France. International Journal for Parasitology, 40, 193--200. IBGE, 2002. Instituto Brasileiro de Geografia e Estatística: Produção da Pecuária Municipal 2002, 30, Brasil. http://biblioteca.ibge.gov.br/visualizacao/periodicos/84/ppm_2002_v30_br.pdf IBGE, 2010. Instituto Brasileiro de Geografia e Estatística. http://www.ibge.gov.br/home/estatistica/economia/ppm/2010/tabelas_pdf/tab17.pdf IBGE, 2012. Instituto Brasileiro de Geografia e Estatística: Produção da Pecuária Municipal 2012, 40, Brasil. http://biblioteca.ibge.gov.br/visualizacao/periodicos/84/ppm_2012_v40_br.pdf Lemeshow, S., Hosmer, D.W., 1984. Estimating odds ratios with categorically scaled covariates in multiple logistic regression analysis. American Journal of Epidemiology, 119 (2), 147--151. Luciano, D.M., Menezes, R.C., Ferreira, L.C., Nicolau, J.L., das Neves, L.B., Luciano, R.M., Dahroug, M.A.A., Amendoeira, M.R.R., 2011. Seroepidemiology of toxoplasmosis in goats and sheep from three counties of Rio de Janeiro state, Brazil. Pesquisa Veterinária Brasileira, 31 (7), 569--574. Martins, G., Penna, B., Hamond, C., Leite, R.C., Silva, A., Ferreira, A., Brandão, F., Oliveira, F., Lilenbaum, W., 2012. Leptospirosis as the most frequent infectious disease impairing productivity in small ruminants in Rio de Janeiro, Brazil. Tropical Animal Health and Production, 44 (4), 773--777. Mendonça, C.E.D’.A., Barros, S.L.B., Guimarães, A.A., Ferraudo, A.S., Munhoz, A.D., 2013. Prevalence and risk factors associated to ovine toxoplasmosis in northeastern Brazil. Revista Brasileira de Parasitologia Veterinária, 22 (2), 230--234. Moraes, L. M., Raimundo, J. M., Guimarães, A., Santos, H.A., Macedo Junior, G. de L., Massard, C. L., Machado, R. Z., Baldani, C.D., 2011. Occurrence of anti-Neospora caninum and anti-Toxoplasma gondii IgG antibodies in goats and sheep in western Maranhão, Brazil. Revista Brasileira de Parasitologia Veterinária, 20 (4), 312--317. Ogawa, L., Navarro, I. T., Freire, R. L., Oliveira, R. C., Vidotto, O., 2003. Ocorrência de anticorpos anti-Toxoplasma gondii em ovinos da região de Londrina no Estado do Paraná. Semina: Ciências Agrárias, 24 (1), 57--62. Sakata, F.B.L.S., Bellato, V., Sartor, A.A., de Moura, A.B..., de Souza, A.P., Farias, J.A., 2012. Toxoplasma gondii antibodies sheep in Lages, Santa Catarina, Brazil, and comparison using IFA and ELISA. Revista Brasileira de Parasitologia Veterinária, 21 (3), 196--200. Silva, A.V., Cunha, E.L.P., Meireles, L.R., Gottschalks, A., Motta, R.A., Langoni, H., 2003. Toxoplasmose em ovinos e caprinos: estudo soroepidemiológico em duas regiões do Estado de Pernambuco, Brasil. Ciência Rural, 33 (1), 115--119. Tesolini, P.M.A., Leão, A.G.C., Beltrame, M.A.V., Gumeiro, M.V., Barioni. G., 2012. Soroprevalência de anticorpos anti-Toxoplasma gondii em ovinos da raça Santa Inês na região da Grande Vitória, estado do Espírito Santo. Revista Brasileira de Ciência Veterinária, 19 (1), 38--41 Ueno, T.E., Gonçalves, V.S., Heinemann, M.B., Dilli, T.L., Akimoto, B.M., de Souza, S.L., Gennari, S.M., Soares, R.M., 2009. Prevalence of Toxoplasma gondii and Neospora caninum infections in sheep from Federal District, central region of Brazil. Tropical Animal Health and Production, 41 (4), 547--552. Van Der Puije, W.N.A., Bosompem, K.M., Canacoo, E.A., Wastling, J.M., Akanmori, B.D., 2000. The prevalence of anti-Toxoplasma gondii antibodies in Ghanaian sheep and goats. Acta Tropica, 76 (1), 21--26.