Beneficial estrogen-like effects of ginsenoside Rb1, an active component of Panax ginseng, on neural 5-HT disposition and behavioral tasks in ovariectomized mice

European Journal of Pharmacology - Tập 659 - Trang 15-25 - 2011
Kun Hao1, Ping Gong1, Shi-Qing Sun1, Hai-Ping Hao1, Guang-Ji Wang1, Yue Dai2, Yan Liang1, Lin Xie1, Fei-Yan Li1
1Key Lab of Drug Metabolism & Pharmacokinetics, China Pharmaceutical University, Nanjing, PR China
2College of Traditional Chinese Materia Medica, China Pharmaceutical University, Nanjing, PR China

Tài liệu tham khảo

Aenlle, 2009, Estrogen effects on cognition and hippocampal transcription in middle-aged mice, Neurobiol. Aging., 30, 932, 10.1016/j.neurobiolaging.2007.09.004 Amin, 2005, Effect of estrogen–serotonin interactions on mood and cognition, Behav. Cogn. Neurosci. Rev., 4, 43, 10.1177/1534582305277152 Anisman, 1979, Deficits of escape performance following catecholamine depletion: implications for behavioral deficits induced by uncontrollable stress, Psychopharmacology (Berl), 64, 163, 10.1007/BF00496057 Ardis, 2009, Effect of acute tryptophan depletion on noradrenaline and dopamine in the rat brain, J. Psychopharmacol., 23, 51, 10.1177/0269881108089597 Attele, 1999, Ginseng pharmacology: multiple constituents and multiple actions, Biochem. Pharmacol., 58, 1685, 10.1016/S0006-2952(99)00212-9 Centeno, 2007, Serotonin in microdialysate from the mediobasal hypothalamus increases after progesterone administration to estrogen primed macaques, Eur. J. Pharmacol., 555, 67, 10.1016/j.ejphar.2006.10.027 Cervo, 1991, Effect of chronic treatment with 8-OH-DPAT in the forced swimming test requires the integrity of presynaptic serotonergic mechanisms, Psychopharmacology (Berl), 103, 524, 10.1007/BF02244253 Chakrabarti, 1998, Modulation of monoamine oxidase activity in different brain regions and platelets following exposure of rats to methylmercury, Neurotoxicol. Teratol., 20, 161, 10.1016/S0892-0362(97)00104-9 Chan, 2002, Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng, J. Clin. Endocrinol. Metab., 87, 3691, 10.1210/jcem.87.8.8717 Chen, 2004, Genistein enhances insulin-like growth factor signaling pathway in human breast cancer (MCF-7) cells, J. Clin. Endocrinol. Metab., 89, 2351, 10.1210/jc.2003-032065 Cho, 2004, Ginsenoside-Rb1 from Panax ginseng C.A. Meyer activates estrogen receptor-alpha and -beta, independent of ligand binding, J. Clin. Endocrinol. Metab., 89, 3510, 10.1210/jc.2003-031823 Dang, 2009, Antidepressant effects of ginseng total saponins in the forced swimming test and chronic mild stress models of depression, Prog. Neuropsychopharmacol. Biol. Psychiatry., 33, 1417, 10.1016/j.pnpbp.2009.07.020 Fadda, 2000, Tryptophan-free diets: a physiological tool to study brain serotonin function, News. Physiol. Sci., 15, 260 Fadda, 2000, A physiological method to selectively decrease brain serotonin release, Brain Res. Brain. Res. Protoc., 5, 219, 10.1016/S1385-299X(00)00016-7 Fernandez, 2008, Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors, J. Neurosci., 28, 8660, 10.1523/JNEUROSCI.1968-08.2008 Gao, 2010, Ginsenoside Rb1 regulates the expressions of brain-derived neurotrophic factor and caspase-3 and induces neurogenesis in rats with experimental cerebral ischemia, J. Ethnopharmacol., 132, 393, 10.1016/j.jep.2010.07.033 Gilbert, 1995, Elevated aromatic-L-amino acid decarboxylase in human carcinoid tumors, Biochem. Pharmacol., 50, 845, 10.1016/0006-2952(95)02006-X Graeff, 1996, Role of 5-HT in stress, anxiety, and depression, Pharmacol. Biochem. Behav., 54, 129, 10.1016/0091-3057(95)02135-3 Hamon, 1981, The respective roles of tryptophan uptake and tryptophan hydroxylase in the regulation of serotonin synthesis in the central nervous system, J. Physiol. Paris., 77, 269 Han, 2006, Oral absorption of ginsenoside Rb1 using in vitro and in vivo models, Planta. Med., 72, 398, 10.1055/s-2005-916211 Heyes, 1988, Quantification of 3-hydroxykynurenine in brain by high-performance liquid chromatography and electrochemical detection, J. Chromatogr., 428, 340, 10.1016/S0378-4347(00)83925-0 Holmes, 1988, Determination of serum kynurenine and hepatic tryptophan dioxygenase activity by high-performance liquid chromatography, Anal. Biochem., 172, 518, 10.1016/0003-2697(88)90478-2 Iivonen, 2006, Effects of estradiol on spatial learning, hippocampal cytochrome P450 19, and estrogen alpha and beta mRNA levels in ovariectomized female mice, Neuroscience, 137, 1143, 10.1016/j.neuroscience.2005.10.023 Imwalle, 2005, Lack of functional estrogen receptor beta influences anxiety behavior and serotonin content in female mice, Physiol. Behav., 84, 157, 10.1016/j.physbeh.2004.11.002 Inagaki, 2010, Acute estrogen treatment facilitates recognition memory consolidation and alters monoamine levels in memory-related brain areas, Horm. Behav., 58, 415, 10.1016/j.yhbeh.2010.05.013 Itoh, 1989, Effects of Panax ginseng root on the vertical and horizontal motor activities and on brain monoamine-related substances in mice, Planta. Med., 55, 429, 10.1055/s-2006-962058 Karas, 1998, Growth factor activation of the estrogen receptor in vascular cells occurs via a mitogen-activated protein kinase-independent pathway, J. Clin. Invest., 101, 2851, 10.1172/JCI1416 Kato, 1995, Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase, Science, 270, 1491, 10.1126/science.270.5241.1491 Kim, 1999, Inhibition by ginsenosides Rb1 and Rg1 of cocaine-induced hyperactivity, conditioned place preference, and postsynaptic dopamine receptor supersensitivity in mice, Pharmacol. Biochem. Behav., 63, 407, 10.1016/S0091-3057(99)00020-9 Kimura, 1994, Interactions of ginsenosides with ligand-bindings of GABA(A) and GABA(B) receptors, Gen. Pharmacol., 25, 193, 10.1016/0306-3623(94)90032-9 Lau, 2008, Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway, J. Steroid. Biochem. Mol. Biol., 108, 64, 10.1016/j.jsbmb.2007.06.005 Lee, 1997, Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells, J. Endocrinol., 152, 39, 10.1677/joe.0.1520039 Lee, 2003, A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells, J. Steroid. Biochem. Mol. Biol., 84, 463, 10.1016/S0960-0760(03)00067-0 Liu, 2010, Ginsenoside Rg1 promotes glutamate release via a calcium/calmodulin-dependent protein kinase II-dependent signaling pathway, Brain. Res., 1333, 1, 10.1016/j.brainres.2010.03.096 Lowry, 1951, Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6 Lu, 2003, Determination of the Five neurotransmitter in mice brain by RP-HPLC method with Fluorescence Detection, Acta. pharmaceutical. science. of. liberation. army., 19, 262 Lu, 2008, Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway, Acta. Pharmacol. Sin., 29, 1209, 10.1111/j.1745-7254.2008.00874.x MacQueen, 2001, The selective serotonin reuptake inhibitor sertraline: its profile and use in psychiatric disorders, CNS. Drug. Rev., 7, 1, 10.1111/j.1527-3458.2001.tb00188.x Martin, 1990, Antidepressant-like action of 8-OH-DPAT, a 5-HT1A agonist, in the learned helplessness paradigm: evidence for a postsynaptic mechanism, Behav. Brain. Res., 38, 135, 10.1016/0166-4328(90)90011-3 Min, 2003, Red ginseng inhibits exercise-induced increase in 5-hydroxytryptamine synthesis and tryptophan hydroxylase expression in dorsal raphe of rats, J. Pharmacol. Sci., 93, 218, 10.1254/jphs.93.218 Nakagawasai, 2009, Subchronic stress-induced depressive behavior in ovariectomized mice, Life. Sci., 84, 512, 10.1016/j.lfs.2009.01.009 Pandaranandaka, 2009, Differential effects of exogenous and endogenous estrogen on anxiety as measured by elevated T-maze in relation to the serotonergic system, Behav. Brain. Res., 198, 142, 10.1016/j.bbr.2008.10.043 Popov, 2006, Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection, J. Clin. Invest., 116, 3160, 10.1172/JCI28996 Porsolt, 1978, “Behavioural despair” in rats and mice: strain differences and the effects of imipramine, Eur. J. Pharmacol., 51, 291, 10.1016/0014-2999(78)90414-4 Qian, 2009, Protective effect of ginsenoside Rb1 on beta-amyloid protein(1–42)-induced neurotoxicity in cortical neurons, Neurol. Res., 31, 663, 10.1179/174313209X385572 Radad, 2004, Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate, Brain. Res., 1021, 41, 10.1016/j.brainres.2004.06.030 Riedel, 1999, Tryptophan depletion in normal volunteers produces selective impairment in memory consolidation, Psychopharmacology (Berl), 141, 362, 10.1007/s002130050845 Riederer, 2004, Clinical applications of MAO-inhibitors, Curr. Med. Chem., 11, 2033, 10.2174/0929867043364775 Rosa, 2003, Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice, Neurosci. Lett., 341, 217, 10.1016/S0304-3940(03)00187-3 Rubinsztein, 2001, Acute dietary tryptophan depletion impairs maintenance of “affective set” and delayed visual recognition in healthy volunteers, Psychopharmacology (Berl), 154, 319, 10.1007/s002130000655 Rueter, 1997, A critical review of 5-HT brain microdialysis and behavior, Rev. Neurosci., 8, 117, 10.1515/REVNEURO.1997.8.2.117 Rutten, 2007, The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat, Psychopharmacology (Berl), 192, 275, 10.1007/s00213-006-0697-4 Schmitt, 2000, Tryptophan depletion impairs memory consolidation but improves focussed attention in healthy young volunteers, J. Psychopharmacol., 14, 21, 10.1177/026988110001400102 Schroder, 2003, Neurotoxic methamphetamine regimen severely impairs recognition memory in rats, Synapse, 49, 89, 10.1002/syn.10210 Szelenyi, 2002, Immunomodulatory effect of antidepressants, Curr. Opin. Pharmacol., 2, 428, 10.1016/S1471-4892(02)00173-X Takikawa, 1999, Interferon-gamma-dependent/independent expression of indoleamine 2,3-dioxygenase. Studies with interferon-gamma-knockout mice., Adv. Exp. Med. Biol., 467, 553, 10.1007/978-1-4615-4709-9_68 Tsang, 1985, Ginseng saponins: influence on neurotransmitter uptake in rat brain synaptosomes, Planta. Med., 221, 10.1055/s-2007-969463 Uchida, 2007, Chronic reduction in dietary tryptophan leads to a selective impairment of contextual fear memory in mice, Brain. Res., 1149, 149, 10.1016/j.brainres.2007.02.049 Wang, 2009, Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins, Neurochem. Int., 54, 43, 10.1016/j.neuint.2008.10.003 Wei, 2009, Determination of Five Monoamine Neuro transmitters in Blood and Cerebral Tissue s o f the Rats by HPLC with Fluorescence Detection, Chinese. archives. of. traditional. Chinese. medicine., 27, 1942 Xu, 2009, Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway, Br. J. Pharmacol., 158, 738, 10.1111/j.1476-5381.2009.00361.x Xue, 2006, Ginsenoside Rb1 promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway, Brain. Res., 1106, 91, 10.1016/j.brainres.2006.05.106 Youdim, 2006, Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness, Br. J. Pharmacol., 147, S287, 10.1038/sj.bjp.0706464 Yuan, 1998, Modulation of American ginseng on brainstem GABAergic effects in rats, J. Ethnopharmacol., 62, 215, 10.1016/S0378-8741(98)00066-X Zhang, 1990, Preliminary study on antiamnestic mechanism of ginsenoside Rg1 and Rb1, Chin. Med. J. (Engl), 103, 932 Zhu, 2009, Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors, Behav. Brain. Res., 196, 200, 10.1016/j.bbr.2008.08.039