Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells

Fitoterapia - Tập 92 - Trang 230-237 - 2014
Yan Zhou1,2, Shijie Cao3, Ying Wang1, Peixiang Xu1, Jiankun Yan3, Wen Bin1, Feng Qiu3, Ning Kang1
1Department of Biochemistry and Molecular Biology, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, PR China
2Department of Neurology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou 221004, PR China
3Department of Natural Products Chemistry, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, PR China

Tài liệu tham khảo

D'Agostino, 2000, Primary and subsequent coronary risk appraisal: new results from the Framingham study, Am Heart J, 139, 272, 10.1016/S0002-8703(00)90236-9 2011, Ministry of Health of the People's Republic of China Jain, 2007, The biology and chemistry of hyperlipidemia, Bioorg Med Chem, 15, 4674, 10.1016/j.bmc.2007.04.031 2001, Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), JAMA, 285, 2486, 10.1001/jama.285.19.2486 Maxfield, 2010, Cholesterol, the central lipid of mammalian cells, Curr Opin Cell Biol, 22, 422, 10.1016/j.ceb.2010.05.004 Costet, 2010, Molecular pathways and agents for lowering LDL-cholesterol in addition to statins, Pharmacol Ther, 126, 263, 10.1016/j.pharmthera.2010.02.006 2005, Chinese Pharmacopeia Committee, 1, 213 Taylor, 1995, Berberine inhibition of electrogenic ion transport in rat colon, Brit J Pharmacol, 116, 2667, 10.1111/j.1476-5381.1995.tb17224.x Kaneda, 1991, In vitro effects of berberine sulphate on the growth and structure of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis, Ann Trop Med Parasitol, 85, 417, 10.1080/00034983.1991.11812586 Iizuka, 2000, Inhibitory effect of Coptidis Rhizoma and berberine on the proliferation of human esophageal cancer cell lines, Cancer Lett, 148, 19, 10.1016/S0304-3835(99)00264-5 Ckless, 1995, Inhibition of in-vitro lymphocyte transformation by the isoquinoline alkaloid berberine, J Pharm Pharmacol, 47, 1029, 10.1111/j.2042-7158.1995.tb03291.x Sanchez-Chapula, 1996, Increase in action potential duration and inhibition of the delayed rectifier outward current IK by berberine in cat ventricular myocytes, Brit J Pharmacol, 117, 1427, 10.1111/j.1476-5381.1996.tb15302.x Kong, 2004, Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins, Nat Med, 10, 1344, 10.1038/nm1135 Holy, 2009, Berberine, a natural lipid-lowering drug, exerts prothrombotic effects on vascular cells, J Mol Cell Cardiol, 46, 234, 10.1016/j.yjmcc.2008.10.011 Yin, 2008, Traditional Chinese medicine in treatment of metabolic syndrome, Endocr Metab Immune Disord Drug Targets, 8, 99, 10.2174/187153008784534330 Wang, 2005, Kinetic difference of berberine between hippocampus and plasma in rat after intravenous administration of Coptidis rhizoma extract, Life Sci, 77, 3058, 10.1016/j.lfs.2005.02.033 Pan, 2002, The involvement of P-glycoprotein in berberine absorption, Pharmacol Toxicol, 91, 193, 10.1034/j.1600-0773.2002.t01-1-910403.x Miyazaki, 1978, Quantitative analysis of berberine in urine samples by chemical ionization mass fragmentography, J Chromatogr, 152, 79, 10.1016/S0021-9673(00)85336-4 Chen, 1995, Determination of berberine in plasma, urine and bile by high-performance liquid chromatography, J Chromatogr B, 665, 117, 10.1016/0378-4347(94)00517-9 Zuo, 2006, Pharmacokinetics of Berberine and its main metabolites in conventional and perm-free rats determined by liquid chromatography/ion trap mass spectrometry, Drug Metab Dispos, 34, 2064, 10.1124/dmd.106.011361 Qiu, 2008, Isolation and identification of urinary metabolites of berberine in rats and humans, Drug Metab Dispos, 36, 2159, 10.1124/dmd.108.021659 Issandou, 2004, Up-regulation of low-density lipoprotein receptor in human hepatocytes is induced by sequestration of free cholesterol in the endosomal/lysosomal compartment, Biochem Pharmacol, 67, 2281, 10.1016/j.bcp.2004.03.006 Lee, 2007, Berberine-induced LDLR up-regulation involves JNK pathway, Biochem Biophys Res Commun, 362, 853, 10.1016/j.bbrc.2007.08.060 Li, 2009, Berberine analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure-activity relationships, and cholesterol-lowering efficacy, J Med Chem, 52, 492, 10.1021/jm801157z Li, 2012, Chemical constituents from the decoction of Coptis chinensis Franch, J Shenyang Pharm Univ, 29, 193 Cameron, 2008, Berberine decreases PCSK9 expression in Hep G2 cells, Atherosclerosis, 201, 266, 10.1016/j.atherosclerosis.2008.02.004 Yu, 2000, Determination and preliminary studies of metabolism of berberine in human urine after oral administration, Chin J Clin Pharm, 16, 36 Tsai, 2004, Hepatobiliary excretion of berberine, Drug Metab Dispos, 32, 405, 10.1124/dmd.32.4.405 Cao, 2013, Berberine metabolites exhibit triglyceride-lowering effects via activation of AMP-activated protein kinase in Hep G2 cells, J Ethnopharmacol, 149, 576, 10.1016/j.jep.2013.07.025 Li, 2011, Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes, J Transl Med, 9, 62, 10.1186/1479-5876-9-62 Brown, 1986, A receptor-mediated pathway for cholesterol homeostasis, Science, 232, 34, 10.1126/science.3513311