The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

Adams, 1991, TPA-induced activation of MAP kinase, FEBS Lett., 290, 77, 10.1016/0014-5793(91)81230-6 Adler, 1992, Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain, 89, 5341 Alexandropoulos, 1992, v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements, Nucl. Acids Res., 20, 2355, 10.1093/nar/20.9.2355 Alvarez, 1991, Pro-Leu-Ser/Thr-Pro is a consensus primary sequence for substrate protein phosphorylation: characterization of the phosphorylation of c-myc and c-jun proteins by an epidermal growth factor receptor threonine 669 protein kinase, J. Biol. Chem., 266, 15277, 10.1016/S0021-9258(18)98613-8 Binetruy, 1991, Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain, Nature, 351, 122, 10.1038/351122a0 Boyle, 1991, Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates, Meth. Enzymol., 201, 110, 10.1016/0076-6879(91)01013-R Coull, 1991, Functionalized membrane supports for covalent protein microsequence analysis, Anal. Biochem., 194, 110, 10.1016/0003-2697(91)90157-O Dalton, 1992, Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element, Cell, 68, 597, 10.1016/0092-8674(92)90194-H Dent, 1992, Activation of mitogen-activated protein kinase by v-raf in NIH 3T3 cells and in vitro, Science, 257, 1404, 10.1126/science.1326789 de Vries-Smits, 1992, Involvement of p21ras in activation of extracellular signal-regulated kinase 2, Nature, 357, 602, 10.1038/357602a0 Fujii, 1989, Gene regulation by tyrosine kinases: Src protein activates various promoters, including c-fos, Mol. Cell. Biol., 9, 2493, 10.1128/MCB.9.6.2493 Fukumoto, 1990, Activation of the c-fos serum-response element by the activated c-Ha-ras protein in a manner independent of protein kinase C and cAMP-dependent protein kinase, J. Biol. Chem., 265, 774, 10.1016/S0021-9258(19)40117-8 Gauthier-Rouviere, 1990, ras-induced c-fos expression and proliferation in living rat fibroblasts involves C-kinase activation and the serum response element pathway, EMBO J., 9, 171, 10.1002/j.1460-2075.1990.tb08093.x Gille, 1992, Phosphorylation of p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter, Nature, 358, 414, 10.1038/358414a0 Gilman, 1988, The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP, Genes Dev., 2, 394, 10.1101/gad.2.4.394 Graham, 1991, Distinct protein targets for signals acting at the c-fos serum response element, Science, 251, 189, 10.1126/science.1898992 Haycock, 1992, ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ, 89, 2365 Herrera, 1989, Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction, Nature, 340, 68, 10.1038/340068a0 Hill, 1993, Functional analysis of a growth factor-responsive transcription factor complex, Cell, 73, 10.1016/0092-8674(93)90238-L Hipskind, 1991, Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF, Nature, 354, 531, 10.1038/354531a0 Howe, 1992, Activation of the MAP kinase pathway by the protein kinase raf, Cell, 71, 335, 10.1016/0092-8674(92)90361-F Hunter, 1992, The regulation of transcription by phosphorylation, Cell, 70, 375, 10.1016/0092-8674(92)90162-6 Jamal, 1990, Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals, Nature, 344, 463, 10.1038/344463a0 Janknecht, 1992, Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties, EMBO J., 11, 1045, 10.1002/j.1460-2075.1992.tb05143.x Kaibuchi, 1989, Activation of the serum response element and 12-O-tetradecanoylphorbol-13-acetate response element by the activated c-raf-1 protein in a manner independent of protein kinase C, J. Biol. Chem., 264, 20855, 10.1016/S0021-9258(19)30013-4 Kalderon, 1984, A short amino acid sequence able to specify nuclear location, Cell, 39, 499, 10.1016/0092-8674(84)90457-4 Kameshita, 1989, A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel, Anal. Biochem., 183, 139, 10.1016/0003-2697(89)90181-4 Kolch, 1991, Raf-1 protein kinase is required for growth of induced NIH/3T3 cells, Nature, 349, 426, 10.1038/349426a0 Konig, 1991, Cell-type specific multiprotein complex formation over the c-fos serum response element in vivo: ternary complex formation is not required for the induction of c-fos, Nucl. Acids Res., 19, 3607, 10.1093/nar/19.13.3607 Kyriakis, 1992, Raf-1 activates MAP kinase-kinase, Nature, 358, 417, 10.1038/358417a0 Laursen, 1989, A second generation solid-phase sequencer, 61 Leevers, 1992, Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein, EMBO J., 11, 569, 10.1002/j.1460-2075.1992.tb05088.x Malik, 1991, Epidermal growth factor and other mitogens induce binding of a protein complex to the c-fos serum response element in human astrocytoma and other cells, J. Biol. Chem., 266, 8576, 10.1016/S0021-9258(18)93013-9 Marais, 1992, Casein kinase II phosphorylation increases the rate of serum response factor-binding site exchange, EMBO J., 11, 97, 10.1002/j.1460-2075.1992.tb05032.x Mohun, 1987, Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site, EMBO J., 6, 667, 10.1002/j.1460-2075.1987.tb04806.x Norman, 1988, Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element, Cell, 55, 989, 10.1016/0092-8674(88)90244-9 Patel, 1992, A new method for the isolation of recombinant baculovirus, Nucl. Acids Res., 20, 97, 10.1093/nar/20.1.97 Pulverer, 1991, Phosphorylation of c-jun mediated by MAP kinases, Nature, 353, 670, 10.1038/353670a0 Qureshi, 1991, v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements, J. Biol. Chem., 266, 10802, 10.1016/S0021-9258(18)99089-7 Rao, 1992, A divergent ets-related protein, elk-1, recognizes similar c-ets-1 proto-oncogene target sequences and acts as a transcriptional activator, Oncogene, 7, 65 Rao, 1989, elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints, Science, 244, 66, 10.1126/science.2539641 Sanghera, 1992, Identification of epidermal growth factor Thr-669 phosphorylation site peptide kinases as distinct MAP kinases and p34cdc2, Biochim. Biophys. Acta, 1135, 335, 10.1016/0167-4889(92)90240-C Sassone-Corsi, 1989, ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun, Mol. Cell. Biol., 9, 3174, 10.1128/MCB.9.8.3174 Shaw, 1989, The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter, Cell, 56, 563, 10.1016/0092-8674(89)90579-5 Siegfried, 1990, Altered transcriptional activity of c-fos promoter plasmids in v-raf-transformed NIH 3T3 cells, Mol. Cell. Biol., 10, 6073, 10.1128/MCB.10.11.6073 Smeal, 1991, Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73, Nature, 354, 494, 10.1038/354494a0 Smeal, 1992, Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73, Mol. Cell. Biol., 12, 3507, 10.1128/MCB.12.8.3507 Smith, 1988, Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase, Gene, 67, 31, 10.1016/0378-1119(88)90005-4 Sompayrac, 1981, Efficient infection of monkey cells with DNA of simian virus 40, 78, 7575 Stacey, 1987, Microinjection of transforming ras protein induces c-fos expression, Mol. Cell. Biol., 7, 523, 10.1128/MCB.7.1.523 Sutherland, 1992, Conserved motifs in Fos and Jun define a new class of activation domain, Genes Dev., 6, 1810, 10.1101/gad.6.9.1810 Suzuki, 1989, SPXX, a frequent sequence motif in gene regulatory proteins, J. Mol. Biol., 207, 61, 10.1016/0022-2836(89)90441-5 Thomas, 1992, Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases, Cell, 68, 1031, 10.1016/0092-8674(92)90075-N Treisman, 1990, The SRE: a growth factor responsive transcriptional regulator, Sem. Cancer Biol., 1, 47 Treisman, 1992, Spatial flexibility in ternary complex formation by SRF and its accessory proteins, EMBO J., 11, 4631, 10.1002/j.1460-2075.1992.tb05565.x Wilmot, 1988, Analysis and prediction of the different types of beta-turn in proteins, J. Mol. Biol., 203, 221, 10.1016/0022-2836(88)90103-9 Wood, 1992, ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK, Cell, 68, 1041, 10.1016/0092-8674(92)90076-O