Synthesis and evaluation of quinoline carboxyguanidines as antidiabetic agents

Figures from the International Institute of Diabetes (IID), colleague centre of the World Health Organization (WHO). A-Rahim, 1996, Pharmacology, 52, 135, 10.1159/000139377 Baker, 1972, J. Med. Chem., 15, 233, 10.1021/jm00273a006 Maeda, 1996, Br. J. Pharmacol., 117, 372, 10.1111/j.1476-5381.1996.tb15201.x Büyükbingöl, 1994, Arch. Pharm., 327, 129, 10.1002/ardp.19943270302 All new compounds have been fully characterized by mp, IR, MS or 1H and 13C NMR spectra. The purities were found to be satisfactory for the pharmacological tests. Yamamoto, 1997, Chem. Pharm. Bull., 45, 1282, 10.1248/cpb.45.1282 Bernatowicz, 1992, J. Org. Chem., 57, 2497, 10.1021/jo00034a059 Kappe, 1993, J. Heterocycl. Chem., 30, 1267, 10.1002/jhet.5570300516